海马后的

OBJECTIVE: To observe the changes of choline acetyltransferase activity in rat hippocampus after ischemia-reperfusion.

目的：观察大鼠脑缺血再灌注后海马组织胆碱乙酰基转移酶活力的动态变化。

Objective To investigated the effect of endogenous VEGF gene expression on dentate gyrus neurogenesis after cerebral ischemia in adult rats.

目的 观察缺血性脑损伤后成年大鼠海马内源性VEGF表达对齿状回神经前体细胞增殖水平的影响。

Take 5 off-springs rats in each group randomly after birth on 7, 14, 21 and 28 day respectively and by using immunohistochemistry, detect the NMDAR1 protein expression levels in the regions of pallium, diencephalon and hippocampus.

分别在子鼠出生后第7、14、21、28天每组随机抽取5只子鼠，免疫组化染色测定子鼠大脑皮层、中脑、海马NMDAR1受体蛋白的表达。

Already have experiment evidence indicate, the spontaneity that brain inner nerve pathological mechanism changes worsens being able to not be controlled , hippocampus nerve basic degeneration appears to escape from loss , galotinous cicatrices takes form and moss shape fibre sprouts waiting for plasticity changing being connected with after this may flare up with acute falling sickness very much.

已有实验证据表明，这很可能与急性癫痫发作后，脑内神经病理变化的自发性恶化不能被控制，出现海马神经元变性脱失，胶质瘢痕形成以及苔状纤维发芽等可塑性改变有关。

Methods: Experimental rats were injected with KA (10mg/kg, 5mg/ml) subcutaneously to make status epilepticus model. SE latter 10 day, Use subliminal dosages KA to check falling sickness paroxysm sensibility model; SE latter 10 day , Morris water maze was to evaluate cognitive function in the animals. Changing NPY adopt immunocyte chemistry method to check the rat brain inner is expressed.

本研究给Sprague-Dawley大鼠颈部皮下注射惊厥剂量的红藻氨酸(KA，10mg/kg，5mg/ml)，诱发癫痫持续状态(status epilepticus，SE)， 10天后，用阈下剂量的KA检测癫痫发作敏感性模型；10天后用Morris水迷宫实验检测动物学习记忆功能变化；用免疫组化技术检测动物海马CA1区CA3区NPY表达的变化。

The most sensitive period of alcohol damage is during the brain growth spurt, the last trimenon of mankind fetation and the first two postnatal weeks in the rat.

研究发现酒精损伤的作用最敏感的时期正是脑生长发芽期，在人类为孕后三个月(相当于大鼠新生至生后两周)，在这个时期，短暂的酒精接触便会使皮质、海马、小脑的上百万神经元损害。

Results: The expression level of Brn-4 mRNA started to increase on the 3rd day after fimbria fornix transection.

结果：海马内Brn-4 mRNA的表达量在切割后第3 d开始升高，14 d达到最高水平，随后下降，28 d左右恢复至正常水平。

Results:"Zusanli"(ST 36) acupuncture at acupoint " the gneration of needling sesations " in the experimental group,fMRI-BOLD show belong to the brain limbic system temporal lobe,hippocampus, cingulate gyrus,hypothalamus,insula lobe in the brain there is a corresponding functional areas have different levels of excited stove back at both the central cluster can be seen in small foci excited;in the control group,fMRI-BOLD shows that the brain can be scattered at small punctate foci excited,bilateral post-central point within the sheet can be seen in small foci excited.

结果：在针刺足三里穴"得气"的实验组，fMRI-BOLD显示属于大脑边缘系统的颞叶、海马回、扣带回、下视丘、岛叶中的相应脑功能区有程度不同的兴奋灶，在双侧中央后回可见小簇状兴奋灶；在对照组，fMRI-BOLD显示大脑内可在散在的小点状兴奋灶，双侧中央后回可见小的点片状兴奋灶。

Gliosis is resulted in TLE. The synapse consists of the presynaptic and postsynaptic terminals, which in many synapses are surrounded by glial cell.

颞叶癫痫可导致神经系统胶质增生，突触后终端与胶质细胞之间形成突触，突触后终端的树突棘的形态学的变化引起突触结构的改变，与胶质细胞之间形成的突触为异位突触，引起海马内环路性质的变化，从而提高致痫性。

Histamine deficiency markedly potentiated the acquisition of learning in cued and contextual fear conditioning in the HDCKO mice,but had no effect on cued and contextual fear extinction.However,histamine deficiency potentiated the inhibitory role of morphine withdrawal in cued fear extinction.Consistent with the behavioral results,morphine withdrawal decreased ERK phosphorylation in the amygdala and mPFC but not in the hippocampus of WT and HDCKO mice,and ERK might not be phosphorylad in the amygdale and mPFC of HDCKO mice after the 4th training of cued fear extinction.

但HDCKO小鼠增强了吗啡戒断对线索恐惧记忆消除的抑制作用，与行为学实验结果相一致是，，吗啡戒断能明显降低WT和HDCKO小鼠在线索恐惧记忆消除第4次训练后杏仁核和mPFC脑区的ERK磷酸化水平，但对海马脑区的ERK磷酸化没有作用；HDCKO小鼠在线索恐惧记忆消除训练的第4次训练后杏仁核、mPFC脑区的ERK蛋白没有明显磷酸化激活。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。