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Uncal recess of inferior horn of lateral ventricle as the boundary sign of hippocampal head and amygdale,were displayied 98.3 percent.

钩隐窝作为海马头与杏仁体的分界标志点,98.3%的受试者钩隐窝显示清晰。

Objective: To research the mechanism of TX0201 abstracted from heart-regulating formula in the treatment of rat with Alzheimer′s disease. Method: The rat models of AD were induced by A β1-40 injected into the bilateral amygdale.

中文摘要:目的:观察调心方有效部位TX0201对Aβ1-40双侧杏仁核注射所致的类阿尔茨海默病大鼠模型学习记忆和皮层、海马细胞凋亡相关基因的影响。

Morris water maze, step-through test, and shuttle-box test revealed that the behavioral deficits in APP/PS-1+HNG group were significantly improved than in APP/PS-1+saline group, suggesting that intraperitoneal HNG treatment may ameliorate behavioral deficits associated with hippocampus, amygdale, and cerebrocortex.

应用Morris水迷宫、被动回避和主动回避实验的行为学评定结果表明,APP/PS-1+HNG治疗组较APP/PS-1+生理盐水治疗组的行为学障碍显著减缓,提示HNG可明显改善与海马、杏仁核和皮层相关的空间学习记忆功能、伤害性刺激记忆功能和条件反射性学习记忆功能。

Histamine deficiency markedly potentiated the acquisition of learning in cued and contextual fear conditioning in the HDCKO mice,but had no effect on cued and contextual fear extinction.However,histamine deficiency potentiated the inhibitory role of morphine withdrawal in cued fear extinction.Consistent with the behavioral results,morphine withdrawal decreased ERK phosphorylation in the amygdala and mPFC but not in the hippocampus of WT and HDCKO mice,and ERK might not be phosphorylad in the amygdale and mPFC of HDCKO mice after the 4th training of cued fear extinction.

但HDCKO小鼠增强了吗啡戒断对线索恐惧记忆消除的抑制作用,与行为学实验结果相一致是,,吗啡戒断能明显降低WT和HDCKO小鼠在线索恐惧记忆消除第4次训练后杏仁核和mPFC脑区的ERK磷酸化水平,但对海马脑区的ERK磷酸化没有作用;HDCKO小鼠在线索恐惧记忆消除训练的第4次训练后杏仁核、mPFC脑区的ERK蛋白没有明显磷酸化激活。

ASPS can increase the capability of anti- oxidation in hippocampal neures, which has concentration dependent.

ASPS能提高海马神经细胞的抗氧化能力,并具有一定的浓度依赖性。

ASPS can enhance the expression of OGG1 mRNA and protect the hippocampal neurons from oxidative stress injury.

ASPS能够增强OGG1 mRNA的表达,并对海马神经元氧化损伤有保护作用。

Objective: to probe the effect of dangguishaoyao-san on calcitonin gene-related peptide and somatostatin of vascular dementia mouse.

目的探讨当归芍药散对血管性痴呆小鼠脑海马降钙素基因相关肽和生长抑素含量的影响。

Objective To observe the effect of pentylenetetrazole-kindled epliepsy on rat s learning and memory and the expression of calmodulin dependent protein kinaseⅡ in hippocampal neurons.

目的 观察戊四氮点燃癫痫对大鼠学习记忆功能的影响及海马神经元钙调素依赖性蛋白激酶Ⅱ表达的变化。

Rats were bilaterally implanted with cannulas in the dHP or mPFC and were microinjected with U0126, a specific inhibitor of ERK upstream activator, or vehicle for 7 consecutive days.

结果表明海马ERK信号通路阻断大鼠表现了抑郁症的核心症状快感缺乏和明显的焦虑行为;前额叶皮质ERK信号通路阻断大鼠表现为快感缺乏和活动水平的降低。

After cocultured with PbCl2 and Na2SeO3 respectively and simultaneously,the growth of neurites and survival of neurons were tested.

建立新生Wistar大鼠海马神经元原代无血清培养技术,通过PbCl2,Na2SeO3单独及联合作用,观察神经细胞的生长和存活情况。

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The split between the two groups can hardly be papered over.

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