海马

IL-1βmRNA expression in the developmental brain in Wistar rat: IL-1β mRNA in hippocampus, cerebral cortex and subcortex was detected by postnatal day 1 and gradually increased with development, reached a peak at postnatal day 21, and then gradually decreased to lower level at adult; In P77PMC rat, IL-1β mRNA expression was similar to Wistar rat before postnatal day 14, then gradually increased and surpassed Wistar rat at postnatal day 28, reached a peak in adult.

原位杂交显示谷氨酸诱导Wistar大鼠惊厥和P77PMC大鼠听源性惊厥后脑内IL-1βmRNA表达情况。结果发现，两种不同惊厥模型大鼠惊厥后脑内IL-1βmRNA表达存在明显的差异。谷氨酸引起惊厥诱导脑内皮层、海马和丘脑IL-1βmRNA表达增高的程度远较P77PMC大鼠听源性惊厥为低，而且惊厥后IL-1βmRNA表达增加较慢，于4-8h达高峰，而听源性惊厥可于惊厥后2h迅速达高峰。但两种形式惊厥诱导脑内IL-1βmRNA表达最高的部位均是海马。

Haimahaima对所有人说:alright, only the ones who think i'm real sea horse talk to me then

2楼——摆出一副我是海马我怕谁的姿态，谁知小海马们是软硬不吃

objective to study gastrodia elata blume to effect tau protein,sod,mda expression in gyrus hippocampi and cerebral cortex of experimental mice.methods to inject okadaic acid to mice ventriculus lateralis and to measure tau protein level,sod activity and lipid superoxide mda content of sod control group,oa injection group,oa and gastiodia elata injection solution group.results tau protein of experimental group(p＜0.05/p＞0.05),sod was lower than model group(p＜0.001) and was higher than control group(p＜0.05).conclusion gastrodia elata blume can increase sod activity and reduce tau protein expression and superoxide lipid forming in brain tissue of experimental dementia mice caused by oa.it can prevent and treat ad.

目的 观察天麻对痴呆模型大鼠海马、皮质神经元微管相关蛋白、超氧化物歧化酶和脂质过氧化物丙二醛表达的影响，探讨其治疗阿尔茨海默病(alzheimer disease，ad)的作用机制。方法用冈田酸(okadaic acid，oa)注射大鼠侧脑室造模，测定模型组、实验组、对照组海马和皮质tau蛋白、sod、mda的含量。结果实验组tau蛋白低于模型组(p＜0.001)，高于对照组(p＜0.05)；sod高于模型组(p＜0.001)和对照组(p＜0.05)；mda低于模型组(p＜0.001)，高于对照组(p＜0.05)。结论天麻可增强oa致实验性痴呆大鼠脑组织sod活性，降低mda蓄积和tau蛋白生成，具有防治阿尔茨海默病的作用。

In this experiment, effects of local electrolytic lesion of bilateral anteventral or posterior or antedorsal hippocampus on learning and memory of dark avoidance behavior in rats were observed respectively. The results show that local lesion of different part of hippocampus more or less block rat's learning and memory of this behovioral pattern, particularly anteventral lesion, but their instinct of light avoidance and liking dark is not influenced.

本实验分别观察了局部电解损伤双侧海马的腹前部、后部和背前部对大白鼠避暗行为的学习和记忆的影响，结果表明：局部损伤海马各部可以不同程度地阻碍这种行为模式的学习和记忆，其中以损伤腹前部最为严重，依次是损伤后部和背前部，但是对大白鼠避光嗜暗的本能没有影响。

Results: Neonatal rats in hypoxic-ischemicgroup behaved restlessness, cyanosis, deep and rapid breath, astasia, lethargy, irritation and spasm; There were local pyknosis, fragmentation, dissymmetry, blur or disappearance of nucleoli, raritas of ground substance in left cerebral cortex; but there was no statistic significance in chinese traditional medicine group and sham group. The expression of HIF-1α mRNA in brain tissue of experimental group and chinese traditional medicine group were higher than that in sham group, especially chinese traditional medicine group at 3d; HIF-1α positive cells were found in cerebral cortex and hippocampus. There were more HIF-1α positive cells in experimental group and chinese traditional medicine group and mainly in vascular endothelial cells.

结果 缺氧缺血后大鼠相继表现为烦躁不安、全身发给、呼吸加深加快、站立不稳、嗜睡、激惹或间断发作的痉挛和抽搐；HE染色显示实验组大鼠左侧大脑皮层出现局灶性神经元核固缩，核碎裂，核仁偏位，不清或消失，基质疏松；中药组大鼠脑组织结构基本接近假手术组，无明显水肿和坏死表现；实验组和中药组大鼠脑组织HIF-1α mRNA表达较假手术组明显增加，尤其是中药组实验第3日者；免疫组化显示实验组和中药组各时间点大鼠大脑皮层和海马区均可见不同程度的HIF-1α表达，明显高于假手术组，阳性表达主要在血管内皮细胞，海马和皮层的锥体细胞亦有HIF-1α阳性细胞分布。

Methods By establishing the apoptosis model of primary culture of hippocampal neurons induced by hyperthermia, the dynamic change of concentration Ca(superscript 2+)in hippocampal neurons and the influence to Bcl-2 expression were observed after using chelerythrine chloride which was the special inhibitor of PKC.

通过建立体外高温诱导海马神经细胞原代培养的凋亡模型，应用PKC特异性抑制剂氯化百屈菜红碱，观察海马神经元胞内Ca(上标 2+)浓度的动态变化以及对B淋巴细胞瘤基因2蛋白(Bcl-2)表达的影响。

Yinao Jieyu Prescription and fluoxetine can increase the expression of bFGF and decrease the level of GFAP in the area of hippocampus CA3 and cingulated cortex of model rats.

颐脑解郁方、盐酸氟西汀能增加脑出血后抑郁模型大鼠海马CA3区、扣带皮质bFGF的表达，减少海马CA3区、扣带皮质GFAP的表达。

Proximal dendrites of hippocampal CAI pyramidal neurons receive mainly the inputs from schaffer collateral/associational commissural pathways, whereas the distal dendrites receive mainly the inputs from entorhinal cortex through TA pathways.

由于近端树突接受海马内部侧枝／联合纤维投射的信息，远端树突通过TA通路接受内嗅皮层投射的信息，由此提示，CA1区锥体细胞对来自海马内部和直接来自皮层的信息输入采用了不同的整合方式。

Results: Remarkable pathological changes were found in h ippocampus: Nissl bodies decreased or disappeared, cyton swelled. The water cont ents and the level of LDH and NO were increased in scalded rats. CNTF could rema rkably improve the pathological changes and reduce the increase of LDH, NO a nd the water contents.

结果：大鼠严重烫伤后，脑组织含水量增加，海马出现明显的病理变化，尼氏小体减少或消失，胞体肿胀，LDH和NO的含量增加；给予CNTF后，脑水肿、海马的病理变化有明显改善，并能降低 LDH和NO的含量。

Results: Remarkable pathological changes were found in h ippocampus: Nissl bodies decreased or disappeared, cyton swelled. The water cont ents and the level of LDH and NO were increased in scalded rats. CNTF could rema rkably improve the pathological changes and reduce the increase of LDH, NO a nd the water contents.

结果：大鼠严重烫伤后，脑组织含水量增加，海马出现怎么明显的病理变化，尼氏小体减少或消失，胞体肿胀，LDH和NO的含量增加；给予CNTF后，脑水肿、海马的病理变化有明显改善，并能降低 LDH和NO的含量。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。