海马

Electroencephalographys were detected in SE and SC groups after 2 h of drug injection. Long term potential at perforant pathway and dentate gyrus and EEG were recorded in LE and LC groups after two weeks of drug injection.

注射药物2 h后，SE和SC组检测脑电图；药物注射后2周，LE和LC组检测内嗅区前穿通纤维-海马齿状回长时程增强和EEG。

Increased concentrations to 2×10〓, 2×10〓mol·L〓, securinine potentiated both basal PS and the magnitude of LTP induced by HFS. 2、Effects of securinine on synaptic transmission in freely moving rats Rats were chronically implanted with a stimulating electrode in the perforant path of hippocampus and a recording electrode in the granule cell of dentate gyrus.

一叶萩碱对清醒自由活动大鼠海马齿状回突触传递活动的影响为了更直接的研究学习记忆与突触效能的关系，我们采取慢性种植电极，在大鼠清醒状态下，观察药物对近生理状态下大鼠突触传递的影响。

To elucidate the molecular mechanisms underlying the neural plasticity after CNS injury, the gene expression profile in the rat hippocampus following perforant path transections was explored by several methods including custom differential screening, custom cDNA array and cDNA microarray.

为了阐明中枢神经系统损伤后神经可塑性的分子机制，本实验探索了多种方法，包括传统差异筛库、传统cDNA array和cDNA microarray，对穿通纤维切断后大鼠海马的基因表达图谱进行了研究。

Methods 20 rats were randomly divided into A, B, C, D and E group. The models of cerebral anoxia in group A and C were made by hypopiesia and hypoxia, and the models of hypoxia-reoxgenation were made in group B and D. 24h and 1h before establishment of models, ginsenoside Rb3 was injected peritoneally in rats of group C and D, respectively. The number and form of GABA-like immunoreactive neurons in hippocampus CA1 area of rats after brain hypoxia-reoxgenation were investigated with immunohistochemistry.

將大鼠隨机分为A、B、C、D、E5组，A、C组以低压低氧暴露製作大鼠脑缺氧模型，B、D组为缺氧－复氧模型。C、D组动物分别於制模前24h、1h 2次腹腔注射人参皂甙Rh3溶液；採用免疫组化法，观察各组大鼠在缺氧及缺氧－复氧处理后海马CA1区GABA免疫反应阳性细胞形態及数量的变化，並与正常对照组比较。

RESULTS: The hippocampal neurons were classified into 2 types according to their discharge patterns: phasic and non-phasic neurons.

结果：根据放电形式的不同主要把海马锥体细胞分为两类：位相型和非位相型放电神经元。

Moreover, we established the model of apoptosis induced by corticosterone and explored the effect of gangliosides, which is a active component in pilous antler, on this apoptotic cell model. The effects of gangliosides on neurotransmitter release, neuronal filopodia formation, calcium signal cascade and 5-HTl A receptor-ligand competitive binding were also studied. 2. Theory study: The viewpoint on brain and kidney in traditional Chinese medicine and that in Western medicine were comparatively studied. The essence of the relationship between kidney and brain in traditional Chinese medicine Subsequently, in combination with the analysis on the results in the empirical study, we discussed the essence of the relationship between kidney and brain in traditional Chinese medicine from the viewpoint about the feedback mechanism of hippocampus-hypothalamic-pituitary-adrenal.

体外实验采用糖皮质激素建立神经细胞凋亡模型，研究鹿茸有效成分的干预作用，并从神经递质释放、神经细胞丝状伪足生成、神经细胞钙信号途径、5-HT_(1A)受体配体竞争结合等方面进行机制探讨。2、理论研究：比较中西医学对肾和脑的传统认识以及现代研究，分析中医学中肾和脑的现代科学内涵，结合实验研究结果，从现代生物学海马—下丘脑—垂体—肾上腺轴负反馈机制的角度对中医肾脑相关理论的实质进行探讨。

Objective: To observe the contribution of Qingnao drop pilula to the alteration of myristoylated alanine-rich C kinase substrate mRNA expression in acute multi-infarction hippocampus.

中文摘要：目的：观察清脑滴丸对急性脑缺血海马MARCKS mRNA表达变化的影响，探讨其对急性脑缺血损害的调节作用。

Qingnao drop pilula can alleciate histomorphology lesion of hippocampus when occurring acute multi-infarction, to turn slower MARCKS mRNA expression, may play a neuroprotective effect role through accommodating PKC-MARCKS signal transduction system.

清脑滴丸可以减轻急性脑缺血时海马组织损伤，下调MARCKS mRNA的过高表达，其机制可能是通过调节PKC-MARCKS信号转导系统而起到神经保护作用。

Objective To observe the changes of praxiology and choline acetyltransferase in cerebral cortex, basal forebrain and hippocampi CA1 of rats after ovariectomized and transected hippocampal fimbriafornix and protective effect of premarin on brain.

目的 观察去卵巢痴呆大鼠行为学及额叶皮质、基底前脑、海马CA1区胆碱乙酰转移酶的变化及倍美力对其影响，探讨倍美力的脑保护机制。

Compared to normal controls, it was found that the hippocampus, temporal pole, frontal lobe, temporal lobe, putamen and precuneus exhibited more significant functional connectivity with posterior cingulate cortex in TLE.

研究发现，与正常对照相比，TLE静息时海马、颞极、额叶、颞叶、壳核及楔前叶等脑区与后扣带回的功能连接增强。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。