海马

Mutant mice than in wild-type controls, and tetrodotoxin or bicuculline application abolished the difference between the genotypes. Studies on human oligodendroglioma cells revealed that GABA played a protective role on Ca〓 overload induced by OGD or glutamate and phaclofen, GABA〓 receptor antagonist, could significantly block the protection.

结果表明：①电凝大脑中动脉后Ca〓2.3-／-鼠脑梗死率和缺血后运动障碍明显重于Ca〓2.3+／+鼠；②Ca〓2.3-／-鼠海马脑片CA1区缺氧后钙超载明显高于Ca〓2.3+／+鼠；③Na〓通道阻滞剂TTX和GABA〓受体阻断剂bicuculline可显著缩小遗传表型之间的差异；④GABA对缺氧无糖及谷氨酸所致的人胶质细胞瘤细胞Ca〓超载有明显的保护作用，此作用可被GABA〓受体阻断剂phaclofen拮抗。

The GAP-43 immunoreactive neurons were present in striate cortex, hippocampus, purkinje cells, motor nucleus of trigeminal nerve and superior olivary nucleus.

在成年大鼠脑内，GAP-43阳性神经元出现于纹状皮质、海马、浦肯野细胞、三叉神经运动核、上橄榄核。

Results: 125 I Mel binding sites in optomeninx was the most, in eptochiasm and sniff ball was next

结果 ：视网膜 1 2 5 I- Mel特异结合量最高，视交叉及嗅球次之，其次为下丘脑、海马、脑干；动力学分析表明 Mel与其受体的结合为可逆性结合

Results: 125 I Mel binding sites in optomeninx was the most, in eptochiasm and sniff ball was next; GTPγS dose dependently inhibited the binding.

结果 ：视网膜 1 2 5 I- Mel特异结合量最高，视交叉及嗅球次之，其次为下丘脑、海马、脑干；动力学分析表明 Mel与其受体的结合为可逆性结合；特异性结合分析提示对 Mel呈高度特异性；10和 5 0μm ol/ L GTPγS使 1 2 5 I- Mel特异结合降低。

The effect of propofol on the evoked potential, in terms of orthodromic population spike and hypoxia injury potential, were investigated in the ischemic hippocampal slices.

观察丙泊酚对缺氧海马脑片诱发电位－顺向群峰电位和缺氧损伤电位的影响。

Hewever the caspase-3 expression was still very high in cortex. Conclusion: In KA model the hippocampus amygdala plays a key role in epilepsy. Therefore it provides a mimic optimal conditions for human temporal lobe epilepsy study. Its an effective method of studying the development, change and pathopoiesis of epilepsy. There is a close relationship between NPY and epilepsy. The regulation of NPY via VPA may be one of the antiepilepsy mechanism of mechanism of VPA. Moreover NGF can enhance the caspase-3 expression. Excito-amino acid can aggravate the apoptosis, which may be one of the reason for intractability of epilepsy.

KA模型因其海马杏仁核在癫痈中起核心作用，故具有模拟人类颗叶癫痈的理想条件，是研究癫痈发展变化、致痈机理的有效工具，NPY与癫病有着密切的联系，VPA调节NPY有可能是其抗癫痈机理之一，而NGF对caspase一3表达有促进作用，兴奋性氨基酸可造成细胞凋亡的增加，而凋亡细胞的增多有可能是癫痈久治不愈的原因之一。

Methods］Systemic injection of KA results in forming animal model of epileptic susceptibility, at the same time, treated them with SVHRP,observed the epileptic behavioral processes according Racine seizure stage, and investigated the expression of PENK mRNA by means of RT-PCR.

方法］大鼠颈部皮下注射红藻氨酸，制备癫痫敏感性动物模型后，给予蝎毒耐热蛋白（scorpion venom heat resistant protein，SVHRP）进行干预。通过观察癫痫行为学表现检测SVHRP对癫痫敏感性形成的影响，同时应用RT-PCR技术检测不同处理组大鼠海马内前脑啡肽原表达的变化。

Here we examined the expression of one of the target genes from cDNA array screnning-cystatin C, a major cysteine protease inhibitor of mammalian animals, in the murine hippocampus at 3, 7, 15 and 30 days following perforant path transections.

我们对cDNA array筛选得到的一个靶基因-CystatinC，一个哺乳动物体内主要的半胱氨酸蛋白酶抑制剂，在鼠去内嗅皮层支配3，7，15，30天海马的表达进行了考察。

Glu uptake sites were mainly Located in the target areas of perforant path, mossy fiber and schaffer collaterals.

Glu摄取位点和海马的穿通路传入，苔藓纤维及Schaffer侧枝的投射靶区相吻合。

Cystatin C may be involved in the astroglia-mediated neural plasticity events in the hippocampus following perforant path transections.

Cystatin C可能和去内嗅皮层支配海马内星型胶质细胞介导的神经可塑性事件有关。

But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊！不用提了。提到肉，真是糟透了。