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Li Zhongren,Shen Meihong,Mu Yanyun,et al.Nanjing University of TCM,Jiangsu210029. Objective To explore into the probable mechanism of Alzheimer's diseaseby the acupuncture treatment combined with DGSYS of TCM.Methods Three kinds of model rats with dysmnesia which were made by injected into drug of scopolamine or NaNo 2 in the abdomen separately and injured at the hippocampal CA 1 in brian by drug of quinolinic acid treated by single acupuncture or acupuncture combined with DGSYS of TCM or DGSYS of TCM were observed separately,to compare different influence on dysfunctions of acuquisition and consoli-dation of memory induced by drugs and injure with nimodipineor the normal rats.

目的 探索临床针刺加当归芍药散治疗阿尔采默氏症的可能机理方法通过腹腔注射药物东莨菪碱或亚硝酸钠,或者用奎宁酸损毁脑海马CA 1 区诱发大鼠发生记忆力障碍,造成不同类型的大鼠&痴呆&模型,对照性观察针刺、针刺加DGSYS、DGSYS及NM对记忆障碍功能的影响和与记忆相关实验指标参的变化。

In rat hippocampal slices, TBS induced phosphorylation of p21-activated kinase and its downstream effecter cofilin, signaling proteins that enable actin filament growth.

在鼠海马切片中,短暂快速脉冲刺激导致蛋白激酶21的磷酸化,在它的下游区产生了cofilin ,一种能使肌动蛋白丝生长的信号蛋白。

Effects of medication , electropuncture and integrated electropuncture and medication treatments on BDNF in the CA1 and CA3 of hippocampus of the rat depression model were observed and compared by using immuno - histochemical techniques.

以免疫组化技术显示比较电针结合药物、电针、药物对慢性应激抑郁模型大鼠海马CA1、CA3区BDNF的影响。

There were a few light stain MCP-1 positive cells in right cerebral ependyma at 2h ischemic.

缺血Zh 组在右侧脑室管膜区可见少量低表达MCP-1 阳性细胞;4h 组在海马区也可见散在的低染色的阳性细胞;12h、24h、48h和 72h各组均可见MCP-1 免疫阳性细胞。

The AQP4 and AQP9 positive cells were located in the choroid plexes ependyma hippocampus supraoptic nucleus paraventricular nucleus and other brain areas. The AQP4 and AQP9 were distributed in the cytomembrane, but not stained in the cytoplasm and nuclei.

免疫组化结果显示AQP4和AQP9阳性物质在脉络丛、SFO、室管膜、海马、视上核和室旁核等处表达,表现为胞膜着色,胞浆和胞核不着色,烧伤后各时间段其表达较对照组均有显著增加,在伤后6h达高峰。

The cells from hippocampus, stria-tum, ependyma, thalamus, olfactory bulb, cortex, brain stem and cerebellum of the brain were studied using HE staining and im-munocytochemistry.

应用苏木精-伊红染色和免疫组织化学方法观察人胎脑室管膜下区、海马、纹状体、丘脑、嗅球、皮质、脑干及小脑的Nestin阳性细胞。

The cell from hippocampus, striatum, ependyma, thalamus opticus, olfactory bulb, cortex, brain stem, cerebellum, and spinal cord in human fetal brain were studied using HE staining and immunocytochemistry.

应用HE染色和免疫细胞化学方法观察人胎脑室管膜下区、海马、纹状体、丘脑、嗅球、皮层、脑干、小脑、脊髓的Nestin阳性细胞。

Immunohistochemical results showed FPNl was also present in the endothelium of blood vessels and in the ependymal cells of the brain.

FPNI抗体使细胞的Fe2+释放量减少了约50%。结论: FPNI在脑内分布广泛,主要分布在皮层、海马、黑质致密部、纹状体和疆内侧核等脑区。

However among the experimental groups no positive labeling was found in 2h group, positive cells were labeled in SFO and choroids plexus of lateral ventricles in 6h group, especially in ependymal cells of body part of SFO, but no positive cells were found in the other regions.

观察实验组可见:2小时组未发现阳性结果。6小时组在SFO与侧脑室脉络丛,发现阳性细胞,在SFO体部的室管膜细胞阳性较多;其它部位未见阳性细胞。8小时与16小时组在海马、下丘脑、背侧丘脑、脉络丛等多处均有阳性细胞。

The results demonstrated that, in rat hippocampal slices, propofolinhibits epileptiform activity.

结果显示:在鼠海马横切面,异丙酚能抑制癫痫样活动。

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