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In the past, the investigation about the cognitive disturbance of epilepsy had been mainly on the hippocampus. However, the investigation on cingulate gyrus was relatively less.

以往对于癫痫学习记忆障碍的研究主要集中在海马上,并且肯定了海马与癫痫学习记忆障碍之间的相关性,对于扣带回的研究却相对较少。

Methods Embryonic neural stem cells from the hippocampus and the superior colliculus are cultured in a serum-free medium, and the morphology and multiplication capacity difference are compared.

培养大鼠胚胎海马和上丘源神经干细胞,并进行形态学和增殖能力的比较。

Using the intracellular recording technique for monitoring the excitatory postsynaptic potentials of CA1 pyramidal neuron and delivering an activator of protein kinase C and/or inhibitors of PKC and 〓/calmodulin-dependent protein kinase Ⅱ into postsynaptic cell in hippocampal slices, we studied the role of postsynaptic PKC and CaMKⅡ in long-term potentiation induced by high frequency stimulation at the CA1 synapses made by Schaffer collateral/commissural and perforant pathway afferents.

用电生理学方法在大鼠海马脑片CA1区锥体细胞记录Schaffer侧枝和穿通通路到CA1神经元突触的兴奋性突触后电位,通过送蛋白激酶抑制剂和激活剂进入突触后细胞,我们研究了突触后蛋白激酶C和依赖钙/钙调蛋白的Ⅱ型蛋白激酶在高频刺激诱导的长时程增强产生和维持中的作用。

Objective To study the effect of aluminum on learning and memory and the synaptic interface constructure in hippocampus CA3 area in rats.

目的 探讨铝对大鼠学习记忆的影响及海马CA3区突触界面结构的变化。

In our study,we found thatimmunoprecipitation with an antibody to PICK1 resulted in coprecipitation of GluR2protein.

结果:缺血再灌注损伤后3小时,与假手术组相比,皮质和海马GluR2亚基的表达均尚未发生改变。

After the head is short of blood, cerebrum is coriaceous can detect with the place such as sea horse the expression of NTF, complement of sex of the source outside passing and gene are knocked except wait for a method to confirm they have nerve to protect action.

脑缺血后,大脑皮质和海马等处可检测到NTF的表达,通过外源性补充及基因敲除等方法证实它们具有神经保护功能。

Objective The present study tried to find out the effects of coriaria lactone on the sodium currents of the rat hippocampal neurons and their significance.

目的 研究马桑内酯(coriaria lactone, CL)对大鼠海马神经元钠离子通道电流的影响,探讨该影响在CL致痫中的意义。

Objective: To study the changes in expressions of synaptophysin and glial fibrillary acidic protein after coriaria lactone induced status epilepticus, and the mechanism of SE.

目的:研究马桑内酯所致癫痫持续状态下海马结构内突触体素及胶质原纤维酸性蛋白表达的变化规律,探讨癫痫的发生机制。

The foundation is ion channel activation on cell membrane and ion transmembrane movement, however, whether Ca2+-activated K+ channel involves in epilepsy induced by Coriaria Lactone is still unclear.

目的:以大鼠海马锥体神经元为靶细胞,了解马桑内酯在其致痫机制中对神经元钙激活钾通道的作用。设计:非随机对照实验。

Our objective is to understand the effect of the different epileptogenic matter as penicillin, coriaria lactone, bicuculline on the expression of hippocampus neuron microfilament F-actin and the relation with the gap junctional communication , and explore their significance in the epileptogenesis.

本实验旨在了解致痫剂如:青霉素、马桑内酯、荷包牡丹碱对海马锥体神经元细胞骨架微丝肌动蛋白F-actin的影响,探讨该表达与神经元缝隙连接通道的关系以及它们在癫痫发病中的意义。

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