海马

Results: miR27a was identified as the most stable reference gene by geNorm and Normfinder software. Among the 52 microRNAs detected by real time PCR array, miR-33 and miR-19a were significantly down-regulated, whereas miR-130 were significantly up-regulated in the hippocampus of Ts65 Dn mice as compared with the euploid control mice. The expression of miR-802, which was the trisomy chromosome 16 derived microRNAs, was very low in hippocampus with no difference between the two groups.

结果：geNorm和Normfinder两种方法均选定miR-27a为最稳定的内参照基因，共检测了52种microRNAs，其中miR-33和miR-19a在Ts65Dn小鼠海马组织中表达显著下调，miR-130在Ts65Dn小鼠海马组织中表达显著上调，小鼠16号染色体三体区段包含的miR-802在Ts65Dn小鼠和对照二倍体小鼠海马组织中表达量均低，差异没有统计学意义。

Objective: to observe the difference of lhx8 mrna expression in hippocampi between the fimbria fornix transected rats and normal ones.

目的：探讨切割穹隆海马伞大鼠海马与正常海马内lhx8 mrna表达的差异。

Objective: To investigate the difference of Brn-4 mRNA expression between the fimbria fornix transected rats and normal ones. Methods: 42 SD rats were randomly divided into 7 groups,6 rats in each group.

目的：探讨切割穹窿海马伞大鼠海马与正常海马内Brn-4 mRNA表达的差异。

RT-PCR/Southern blot was used to detect the change of Brn-4 mRNA expression in hippocampus after fimbria fornix transection.

取各组大鼠的海马组织，提取总RNA，采用RT-PCR/Southern 杂交方法分析穹窿海马伞切割后海马内Brn-4 mRNA的表达变化。

Then hippocampi were isolated and total RNA was extracted. RT-PCR/Southern blot was used to detect the change of Brn-4 mRNA expression in hippocampus after fimbria fornix transection.

取各组大鼠的海马组织，提取总RNA，采用RT-PCR/Southern杂交方法分析穹窿海马伞切割后海马内Brn-4 mRNA的表达变化。

Objective: To investigate the difference of Brn-4 mRNA expression between the fimbria fornix transected rats and normal ones.

作者：董传明秦建兵，金国华，王磊，朱蕙霞，田美玲目的：探讨切割穹窿海马伞大鼠海马与正常海马内Brn-4 mRNA表达的差异

The results showed that IFN-γ immunoreactive structures widely distributed in CA1, CA2, CA3 and indusium griseum, which indicates IFN-γ have definite influence on physiological function of hippocampus.

结果表明，IFN-γ免疫反应主要分布于海马CA1、CA2、CA3区，有少量分布于灰被，齿状回。这为海马具有免疫调节功能的观点提供了新的证据。结合文献，推断IFN-γ在海马－下丘脑－垂体－肾上腺的免疫调控中起主要作用。

Through surface-based hippocampal morphologic analyses,we found partial regional atrophy of hippocampus at some degree,mainly localized in the lateral and inferior hippocampus area bilaterally in aMCI compared with NC.

通过基于海马表面的形态分析，发现遗忘型轻度认知损害者的海马部分区域形态有一定程度的萎缩，以双侧海马外侧及下表面的区域性萎缩为特点。

This study explore the neurochemistry mechanism of hippocampal damage induced by psychological stress, and the relationship between hippocampal volume、NAA level and stress responses by Magnetic resonance imaging and spectroscopy in oder to provide experimental basis for the evaluation of mental injury in human.Materia...

本研究旨在强迫游泳应激动物模型的基础上，主要采用磁共振成像技术和磁共振频谱技术在体测定海马体积和NAA水平，探讨应激对海马损害的神经生化机制，应激的强度和海马体积、NAA浓度之间的关系，以期为人类精神刺激所致精神损伤的伤情评定提供实验依据。

Results: 1.Empirical study: The changes of learning and memory performances and hippocampal morphology were related to ageing. Both short-term and long-term administration of excessive glucocorticoids induced the decrease of learning and memory performances and hippocampal neurodegeneration. Adrenalectomy operated during both infancy and senectitude inhibited the hippocampal structure and function.

结果：1、实验研究：动物学习记忆能力及海马的形态与增龄密切相关，短期、长期给予过量糖皮质激素可造成海马退行性改变和学习记忆功能的降低，幼年期糖皮质激素剥夺可影响动物神经发育和功能，老年期长期糖皮质激素剥夺可加重动物海马退行性病变和学习记忆能力下降。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。