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Combining chemical complexation and physics extraction of monobasic and polybasic carboxylic acid, the universal liquid-liquid equilibrium model with clear physical meaning was successfully induced.

详细研究了萃取剂浓度、稀释剂浓度、水相pH值、温度和羧酸初始浓度等因素对络合萃取平衡的影响以及萃取剂的再生条件。

Under the same concentration, tadalafil induce higher ratio of relation responses in the smooth muscles of CRF rabbit cavernosal strips, compared with papaverine and sodium nitroprussiate, with most significant difference occurring under the concentration indicators of 10-5 mol/L and 10-4 mol/L (P.01). Conclusions The effects of tadalafil on relaxation responses in CRF rabbit cavernosal strips highly depend on its concentration. The effect of tadalafil on relaxation responses in CRF rabbit cavernosal strips is better than that of papaverine and sodium nitroprussiate. Tadalafil may be an effective drug for treating CRF reduced erection dysfunction.

同一浓度下,他达拉非对慢性肾功能衰竭兔阴茎海绵体平滑肌舒张百分比与罂粟碱、硝普钠相比较,舒张百分比均大于罂粟碱和硝普钠,且在10~(-5)mol/L、10~(-4)mol/L浓度,他达拉非对慢性肾功能衰竭兔阴茎海绵体平滑肌舒张百分比,与罂粟碱、硝普钠相比较有显著性差异(P<0.01)结论他达拉非对慢性肾功能衰竭兔阴茎海绵体平滑肌舒张反应的影响具有浓度依赖性,他达拉非对慢性肾功能衰竭兔阴茎海绵体平滑肌舒张反应的影响优于罂粟碱及硝普钠,他达拉非可能是治疗慢性肾功能衰竭性阴茎勃起功能障碍的理想药物。

One Nitroso-bacteria named N1(GenBank registered number: EU647556) was isolated from the SBBR one-step completely nitrogen removal process, and was identified as Nitrosomonas sp. The characteristics of N1 were studied. Results showed that the optimal temperature and pH of N1 were 8.0 and 30℃respectively and sufficient dissolved oxygen was demanded.

N1(NCBI数据库中注册号为EU647556),该菌株对氧气需求量存在较严格要求,pH及温度对其氨氧化活性具有明显的影响,最适条件分别为pH8.0和30℃,在氨氮浓度80~800mg/L较宽的底物浓度范围内具有活性,当氨氮浓度高达800mg/L时,其氨氧化活性没有受到明显的抑制。

MBC value was 0.61, 0.304, and 0.00475 μgmL^(-1) respectively. Sterilization rate of ceftiofur suspension was the fastest to Actinobacillus, followed by Streptococcus. PAE of ceftiofur suspension was relatively short to E. coli, which illustrated that it was nonconcentration dependent. PAE was obvious longer to Actinobacillus, which showed that it was concentration dependent, however, it revealed part concentration dependent to streptococcus.

头孢噻呋混悬剂对大肠杆菌、放线杆菌及猪兽疫链球菌的MIC值分别为:0.076、0.304、0.00475μgmL^(-1);MBC值分别为:0.61、0.304、0.00475μgmL^(-1);头孢噻呋混悬剂对放线杆菌的杀菌速率最快,对链球菌次之;头孢噻呋混悬剂对大肠杆菌PAE较短,呈现非浓度依赖性,对放线杆菌的PAE较长,呈明显的浓度依赖性,而对猪兽疫链球菌呈现部分浓度依赖性。

Methods: Thirty ASA I nulliparous women were administered 10 ml bolus of epidural ropivacaine in the first stage of labor. A concentration of 0.5% ropivacaine was applied to the first woman, and the dosage to the next one was up-regulated or down-regulated one level in accordance to the previous woman's response to the concentration.

选择30例单胎足月初产妇,在进入第一产程活跃期时行硬膜外给予罗哌卡因10ml,第1例罗哌卡因的浓度为0.5%,下一产妇的药物浓度根据前一产妇有无运动阻滞情况来上调或下调1个浓度级。

Based on the genomic DNA extracted from Ochotona curzoniae, the effects of the main reaction system elements such as Mg(superscript 2+), dNTPs, primer, template DNA, Taq DNA polymerase and annealing temperature were presented by single factor experiment.

方法]以高原鼠兔基因组DNA为模板,通过单因素试验,对体系中的模板浓度、Mg(上标 2+)浓度、dNTPs浓度、Taq酶用量、引物用量、退火温度进行探讨。

It is also found that the level of IL-18BPa has a negative correlation with PASI score. This finding indicates that IL-18BPa as an inhibitor decreases in the plasma of psoriatic patients.

我们既往的研究发现银屑病血清中存在细胞因子异常,本文的研究发现银屑病患者血浆中IL-18BPa的浓度比正常人减少,进行期血浆中的浓度最低,退行期血浆中的浓度与正常人相近,与银屑病PASI评分呈负相关性,说明在银屑病外周血中存在抑制因子IL-18BPa的下降,IL-18/IL-18BP负反馈环路的异常,使Th1反应增强,可能在银屑病的发病机制中起到重要作用。

The response of HNEC to the stimulation of LPS shows dosage dependence, and stimulation of LPS with suitable concentration benefits HNEC secreting Th1/Th2 cell factors to maintain the balance; The stimulation of LPS with too high and too low concentrations would cause unbalanced secretion of Th1/Th2 cell factors, which might be the pathopoiesis mechanism of gram negative bacilli in chronic rhinitis and rhinosinusitis.

LPS对HNEC的刺激反应与浓度呈剂量依赖性,适当浓度的LPS刺激有利于HNEC分泌的Th1/Th2细胞因子维持平衡状态;过高或过低浓度的LPS刺激可诱导HNEC的Th1/Th2细胞因子失衡分泌,这可能是GNB在慢性鼻、鼻窦炎的致病机理。

Tamarense was studied. 5 mg·L~-1 of N-phenyl-2-naphthylamine was showed to have 50% inhibitory rate on A. tamarense after 3 days. 70 μL·L~-1 of linoleic acid appeared 40% inhibition rate on A. tamarense.70 μL·L~-1 of pelargonic acid had 85% inhibition rate at the 3 rd day with some increase in cell density later on.

结果表明,浓度高于5 mg·L-1以上的N-苯基-2-萘胺,3 d后能保持对塔玛亚历山大藻抑制率超过50%;浓度为70μL·L-1的亚油酸对塔玛亚历山大藻的抑制率约为40%;浓度为70 μL·L-1的壬酸第3天可以达到85%的抑藻率,但随后藻密度有反弹。

Single proton emission computer tomography and X-Ray film were taken to observe the allocation of the drugs.Results (1) Pelvic and periaortic nodal 5-FU concentrations of RP were 60~106 and 76~119 times of that of IP respectively.(2) The nodal 5-FU concentrations on repeated injection side were 16~20 times of that on control sides of RP.(3) There was no complications or adverse effect observed.(4) 5-FU was allocated to the space including the external iliac, internal iliac, obturator, deep inguinal and common iliac lymph nodes and also up to the periaortic lymph nodes.

结果 (1)腹主动脉旁淋巴结5-FU浓度,腹膜后化疗是腹腔化疗的76~119倍;盆腔淋巴结5-FU的浓度,腹膜后化疗是腹腔化疗的66~106倍;(2)腹膜后化疗重复注药,注药侧5-FU浓度为未注药侧的16~20倍;(3)腹膜后化疗与腹腔化疗均无明显的毒副作用;(4)经盆腔腹膜外间隙给药,药物能从盆腔上行至腹主动脉旁淋巴结及其周围。

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