浓度

RESULTS:(1) ET-1 could increase total protein production, surface area, ERKs activity and ［Ca2+］i in cultured cardiomyocyte in dose-dependent manner at concentrations ranging from 10-9 to 10-7 mol/L. And this effect could be abolished by BQ123, an antagonist of ETA receptor, partly inhibited by PTX, but not by BQ788, an antagonist of ETB receptor.（2）The activation of ERKs and the increase of ［Ca2+］i induced by ET-1 were obviously inhibited by PD98059, a selective ERKs kinase inhibitor, and nifedipine, a calcium channel blocker, respectively. Both antagonists partially inhibited ET-1-stimulated cardiomyocyte hypertrophic response.(3) Staurosporine, a selective PKC inhibitor, could inhibit ET-1-stimulated cardiomyocyte hypertrophic response and increase of ［Ca2+］i, but not affect the activation of ERKs.

结果： ①ET-1浓度依赖性增加新生大鼠心肌细胞蛋白质含量和心肌细胞表面积、ERKs活性及［Ca2+］i浓度，以上作用可被ETA受体拮抗剂BQ123所完全抑制，被百日咳毒素部分抑制，而ETB受体拮抗剂BQ788则无效；②ERKs激酶特异性抑制剂PD98059可完全抑制ET-1激活ERKs的作用，钙通道拮抗剂硝苯地平可明显抑制ET-1介导的［Ca2+］i浓度增加，但二者皆仅部分抑制ET-1介导的心肌细胞肥大反应；③蛋白激酶C选择性抑制剂staurosporine并不能明显抑制ET-1介导的ERKs激活，但可抑制ET-1介导的的［Ca2+］i浓度增加及心肌细胞肥大反应。

According to the dynamic process of development in film printing machine,the dynamic mode of the relation between the area of the already-developed film and the developer concentration was established.

根据印刷胶片冲洗机显影动态过程，建立了显影液浓度、显影剂氧化物浓度跟随已冲洗胶片面积变化的动态模型；分析了在一定条件下显影液浓度、显影剂氧化物浓度对印刷胶片显影质量的影响；综合两方面的结果，得出通过观察已冲洗胶片面积、调节补充液补充速度来控制印刷胶片显影质量方法。

According to the dynamic process of development in film printing machine,the dynamic mode of the relation between the area of the already-developed film and the developer concentration was established.The influences of the developer concentration and the oxides concentration on the film development quality were analyzed.

根据印刷胶片冲洗机显影动态过程，建立了显影液浓度、显影剂氧化物浓度跟随已冲洗胶片面积变化的动态模型；分析了在一定条件下显影液浓度、显影剂氧化物浓度对印刷胶片显影质量的影响；综合两方面的结果，得出通过观察已冲洗胶片面积、调节补充液补充速度来控制印刷胶片显影质量方法。

A Development Model of Electron Beam Resist Based on Cellular Automata;2. Progress in Development-free Vapor Photolithography;3. According to the dynamic process of development in film printing machine,the dynamic mode of the relation between the area of the already-developed film and the developer concentration was established.

根据印刷胶片冲洗机显影动态过程，建立了显影液浓度、显影剂氧化物浓度跟随已冲洗胶片面积变化的动态模型；分析了在一定条件下显影液浓度、显影剂氧化物浓度对印刷胶片显影质量的影响；综合两方面的结果，得出通过观察已冲洗胶片面积、调节补充液补充速度来控制印刷胶片显影质量方法。

objective to investigate whether hypoxia preconditioning exist in adipose tissue,and construct the hypoxemic model of adipose tissue.methods after injected different density cocl2 to rat's subcutaneously of groin,use immunohistochemical method detect hif-1α protein,and use rt-pcr detect hif-1α mrna.results after injected different density cocl2,the adipose tissue of rat's groin express different degree of hif-1αprotein and hif-1αmrna.,and reach the peak when the density is 20-40 mg/kg and the time is 3 h.conclusion hypoxia preconditioning exist in adipose tissue,and the effect of preconditioning is most evidence when the density is 20-40 mg/kg and the time is 3 h.

目的 探讨脂肪组织中是否存在缺氧预适应现象，构建cocl2致缺氧的缺氧模型。方法不同浓度的cocl2大鼠腹股沟区皮下层浸润注射，分别用免疫组织化学法和rt-pcr法检测该区脂肪hif-1α蛋白和hif-1α mrna的表达情况。结果用不同浓度的cocl2行化学缺氧后在不同时间点观察有不同程度的hif-1α蛋白和hif-1α mrna表达，其中，在浓度为20～40 mg/kg，时间为3 h时脂肪组织中hif-1α表达达高峰。结论脂肪组织存在缺氧预适应现象；cocl2的浓度选择20～40 mg/kg，时间选择3 h时缺氧预适应效果较佳。

The average concentration is 244 μg/ m3 and 171 μg/ m3, respectively, and the background concentration is 166 μg/ m3 and 110 μg/ m3, respectively. In the iron foundry plant, when the middle frequency furnace opened, the instantaneous PM10 and PM2.5 mass concentrations increased significantly to 10 mg/ m3 and 7 mg/ m3, respectively.

铸造厂中导致PM10与PM2.5微粒质量浓度上升的主要事件为中周波融解炉的开启，瞬间最高浓度分别可达到10 mg/ m3 与7 mg/ m3，平均浓度分别约为615 μg/ m3 与479μg/ m3，背景浓度分别约为84 μg/ m3 与61 μg/ m3。

Diabetes mellitus is a kind of chronic and worldwide disease, and tight glycemic control is critical in manging DM and preventing complications such as nephropathy, neuropathy and retinopathy. In order to relieve DM patients pain and decrease the risk of crossinfection, noninvasive ways to monitor blood glucose concentrations are preferred, and one approach is to monitor glucose concentrations in tear fluid. This review covers recent understanding of features of tear fluid and relevant changes in DM, the influence of different collecting methods in tear glucose concentration, and attempts to monitor tear glucose concentration in situ by using contactlens based sensing devices.

糖尿病（diabetes mellitus，DM）是一种慢性疾病，也是一种全球性疾病，糖尿病患者长期理想控制血糖有助于防止或延缓糖尿病肾病、神经病变和糖尿病视网膜病变等慢性并发症的发生，为了减少患者的痛苦和降低交叉感染发生的危险，人们想到了通过泪糖浓度这一无创指标来监测血糖控制情况的可能性，我们综合近年的相关研究进展，从泪液的特性及糖尿病患者的相关改变、不同收集方法对泪糖浓度的影响及检测泪糖浓度的产品等方面进一步探讨泪糖浓度作为糖尿病病情评价指标的可行性。

The compatibility of both Gvirens and B.firmus was researched. The fermentation filtrate of Gvirens , under the concentration of 70%, had not distinct inhibitory activity to B.firmus, the biomass of B.firmus would decrease with above the 70% filtrate of Gvirens, but the fermentation filtrate of B.firmus had not inhibitive role to Gvirens. 7, The cooperation control of both Gvirens and B.firm to the pine needle blight was explored:(1) Pathogen inoculation happened prior to the bio-control treatment for 7 days, however, the disease index and control effect had not distinct differences in any treatments even if combination of the two antagonists, but the susceptibility for different kind of pine were different.(2)when antagonist and pathogen were inoculated at the same time, some control effect to the pine needle blight, including certain extent cooperation control of both Gvirens and B.firm were proved, but it wasn't distinct when two antagonists used separately, and the change of the antagonist concentration had little effect to the control effect.

G.virens与B.firmus对松赤枯病的协同控制显示：(1)预先接种病菌后(7天)再进行生物防治处理，不管那种情况，感病指数和防治效果在处理间差异不明显，浓度影响无显著差异，即使是两种生防制剂联合作用也未显著提高其防效，但不同树种间的感病性有明显差异；(2)领抗菌与病原菌同时接种，对松赤枯病有一定防治效果，两菌联合有一定的协同作用，两菌分别单独施用防效差异不显著，浓度变化对防效影响不大；(3)预先接种颇抗菌能显著提高防治效果，两菌联合处理防效更优，感病树种的感病指数可降至13一15，抗病树种的感病指数可控制在3%左右；在同一浓度下B.f1'r功US、叹叮厂即s间无显著差异，在同一领抗菌下，浓度愈高，防效愈高：松，(4)三种生防接种方式的平均效果分析表明，叹F行ens最高平均防效49.5%黑 B。

The results show that, the chloride concentrations and diffusion coefficients are both a one-humped function of elevations (can also be the time scale of seawater infiltration), they increase with the increase of elevation until they get to the peak value, and then decrease with the increase of elevation; an evident relationship is being between the surface chloride concentrations and the wave forces acted on the concrete surface, while there is no much difference among the diffusion coefficients; the diffusion coefficients get to bigger as the depth from the concrete surface increase in the influence of the capillary structures evolution and chloride concentration, but this tendency of change was alleviated with the increase of depth.

研究结果表明：氯离子侵蚀混凝土设施的竖向分布规律为氯离子浓度、扩散系数与标高之间同为单峰函数分布，先随高程变大而变大，达到峰值后，随高程变大而减小；氯离子侵蚀混凝土设施的环向分布规律为混凝土构件表面氯离子浓度、氯离子通量与波浪力之间有明显的对应关系，波浪力越大，则表面氯离子浓度和氯离子通量越高，而扩散系数在各方位角差别不明显；由于混凝土长期服役过程中内部毛细孔隙结构演化以及氯离子浓度的影响，氯离子扩散系数随混凝土深度变大而变大，但这种变化趋势随深度逐渐趋缓。

Different fillers for wetlands are chosen by comparison and then matched, the following filler matching is achieved aiming at different influent: for wastewater with low nitrogen concentration and medium or high organic matter concentration, better removal efficiency is attained by combined fillers of coal cinder + pebble stone + gravel; for wastewater with high nitrogen concentration and low organic matter concentration, the optimum combination is fly ash brick crumbs + gravel.

针对不同的进水进行了湿地填料的比选与配伍，获得了适合于不同水质的填料配伍：对于含氮浓度低或中、高有机物浓度的污水，煤渣+砾石+碎石填料组合有较好的去除效果；对于含氮浓度高或有机物浓度低的污水，粉煤灰砖屑+碎石组合有较好的去除效果。

In the United States, chronic alcoholism and hepatitis C are the most common ones.

在美国，慢性酒精中毒，肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题，你可以随时联系我。