活性核

Effects of dietary curcumin or N-acetylcysteine on NF-kappa B activity and contractile performance in ambulatory and unloaded murine soleus.

影响膳食姜黄素或n -乙酰半胱氨酸对核因子-κ b活性和收缩性能，在日间和卸载小鼠比目鱼。

The reactivities of 1 and other long chain oximes with p nitrophenyl diphenyl phosphate, p nitrophenyl diethyl thiophosphate, and O ethyl ( s β diisopropylaminoethyl) methyl phosphonothiolate were studied.

报道了一种新的高亲核长链咪唑肟N 十四烷基咪唑 2 甲醛肟的设计与合成，并比较了它及其他长链咪唑肟与有机磷酸酯二苯基、对硝基苯基磷酸酯、对硫磷及 Vx 的反应活性。

Macroporous tributyl amine aminating strongly basic anion exchange resin-a phase transfer catalyst with high catalytic activity for nucleophilic substitution,which was screened out via combinatorial chemistry method –was used to catalyze the nucleophilic substitution reactions for synthesis of benzyl acetate,benzyl propionate,benzyl butyrate and benzyl valerate.

用组合化学方法筛选出的对无外加碱条件下的亲核取代催化活性最高的聚合物季铵盐–三丁胺胺化强碱性阴离子交换树脂为相转移催化剂，催化合成了乙酸苄酯、丙酸苄酯、丁酸苄酯、戊酸苄酯等羧酸苄酯。

Cytokine-induced killercells are a cluster of alloplasm cells,which are prepared from the mononuclear cells of human peripheral blood that might be stimulated by some kinds of cytokines.The proliferation and cytotoxicity of CIK cells are high,and the side effect is low.CIK cell is a more effective anti-tumor effector cell in adoptive immunotherapy.

细胞因子诱导的杀伤细胞是人外周血单个核细胞在体外经多种细胞因子刺激后获得的一群异质细胞，它具有增殖能力强、杀瘤活性高和杀瘤谱广、临床应用不良反应小的特点，是肿瘤过继免疫治疗中更为有效的杀瘤效应细胞。

Here we summarize the progress of salmon calcitonin's heterogenous expression in prokaryotic and eukaryotic expression systems as well as the amidation of C-terminal. Both the biological activity of salmon calcitonin and the biologic expression system can be improved by genetic engineering techniques.

本文综述了鲑鱼降钙素基因在大肠杆菌、链霉菌、乳酸杆菌和蓝藻等原核细胞，在酵母、昆虫、动植物等真核细胞中异源表达的研究进展，以及通过基因工程的方法能够改进生物表达系统，提高鲑鱼降钙素活性的动态。

Two kinds of highperformance expressions of eukaryotic system of human mutant CD59 cDNA were successfully established, which makes further study of mutant CD59 glycation and anticomplement activity possible, and thus elucidate the mechanism of blood vessel proliferation in diabetes.

成功建立了两种高效表达人CD59突变体的真核表达系统，能够进一步研究人CD59的突变体糖基化及抗补体活性，为阐明糖尿病血管增殖性病变的发病机制奠定了基础。

AIM: To realize an antiricin neutralizing monoclonal antibodybased ScFv proteins with high biological activity in the pCDNA3.1 vector expression system and to evaluate the neutralizing activities of ScFv.

目的：实现基于中和性单抗4C13单链抗体的真核表达，并对其生物学活性进行评价。

METHODS: The total RNA was obtained by TRIzol from an antiricin neutralizing monoclonal antibody hybridoma cell named 4C13 and heavychain and lightchain variable fragments were amplified by overlap PCR and accepted by Genbank of NCBI. VH and VL were linked by3 with a direction of VHlinkerVL and cloned to pCDNA3.1 vector expression system.

用TRIzol提取抗ricin中和性单抗杂交瘤细胞4C13总RNA，扩增其轻、重链可变区基因，登陆GenBank；用Linker3将VH和VL连接，用重叠延伸PCR克隆入真核表达载体pCDNA 3.1，用脂质体转染293T细胞，对瞬时表达产物进行生物学活性检测。

Alterations of hypothalamic AMPK activity augment changes in arcuate neuropeptide expression induced by fasting and feeding.

下丘脑AMPK活性的改变增加了弓状核由禁食和进食所诱导的神经肽表达变化。

The immunohistochemistry test between the hypothalamus arcuate nucleus and the antibody showed that fusion protein had biological activity. This will provide a basis for further study on the biological function of Ghrelin protein to growth and development and fat deposition of cattle.

将获得的血清与黄牛下丘脑弓状核进行免疫组化试验，进一步印证了重组蛋白表达产物是有活性的，为进一步研究黄牛Ghrelin的功能及其对黄牛生长发育和脂肪沉积奠定了基础。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。