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Microglial activation may play a role in the pathogenesis of Huntington's disease.

小神经胶质细胞的活化可能在亨廷顿舞蹈病的病理发生中起一定作用。

Chapter 5 covered the quantum chemistry study of the model molecule (410 atoms) of HupA- Acetylcolinesterase complex at HF/4-31G level with point charge model (1929 point charges) to simulate the environment effect on complex active site.

第五章:用HF/4-31G量子化学方法对单分子状态石杉碱甲、活化状态的石杉碱甲以及石杉碱甲-乙酰胆碱酯酶复合物的模型体系(410原子,1929个点电荷)进行了从头计算研究,指认了对于形成稳定复合物贡献最大的石杉碱甲分子的基团和酶的氨基酸残基,揭示了活性位点中水分子的重要作用。

The growing body of literature regarding this topic has recently progressed from describing the association of hyaluronan and hyaluronidase expression associated with different cancers, to understanding the mechanisms that drive tumor cell activation, proliferation, drug resistance, etc.

越来越多的文学就这一议题最近已从描述协会的透明质酸和透明质酸酶的表达与不同的癌症,理解的机制,推动肿瘤细胞活化,增殖,耐药性等任何一个来源,但是,讨论透明质酸合成和代谢,以及各种因素的平衡调节。

The degradating and redistributing of ECM were migration of VSMC and vascular remodeling through inhibiting the production of PDGF-BB and the activation of MMPs so to prevent the vascular stenosis.⑤Orthotopic hybridism in situ: The expression of MMP-3 increased after operation, the tendency and intensity were parallel to the expression of NF-κB. Tongxinluo could decrease the expression of MMP-3 and NF-κB. The study showed that the producting and activating of MMP-3 were modulated by NF-κB. The inhibition to the producting and activating of MMp-3 of Tongxinluo was mediated by inhibiting the activating of NF-κB. Conclusion ①The rabbit vascular stenosis model could be established successfully by plain balloon damage, the operation process was easy, economical and practical.

①单纯球囊损伤可成功建立典型家兔血管狭窄模型,操作方法简单,经济实用;②以VSMC增殖、迁移为主的内膜增厚以及以ECM降解、合成与再分布所致的血管重构是导致受损血管狭窄的根本原因;③通心络能明显抑制VSMC的增殖、迁移和ECM降解、合成,阻止血管内膜增生和血管重构,防止受损血管狭窄;该作用可能与其减少和阻止PDGF-BB的产生和活性,以及抑制MMPs的表达和恢复MMPs/TIMPs平衡有关;④通心络能显著抑制球囊损伤后血管内膜增生和血管重构,可能与其保护血管内皮,改善内皮功能,增加血清NO含量有关;⑤通心络抑制内膜增生和血管重构,减轻受损血管狭窄,还可能是通过抑制NF-κB的活化途径而起作用的。

Hydrocyanic acid and water proceed via a five-centred transition states then transformed by its exterior hydrogen-bond; The results show that the activation energy of the isomerizing reaction in the aqueous phase is lower than that in the gas phase. It is likely that the hydrogen bonds formed in the complexes and the solvent effect play an important role.

计算结果表明,在水相中异构化过程的活化能比在气相中低,无论在气相还是在水相中异氢氰酸通过水氢键转化成氢氰酸容易些,而氢氰酸由水氢键转化成异氢氰酸相对要困难些,分子间氢键和溶剂化效应在异构化反应过程中起到重要的作用。

By improving the chemical reaction between Potassium Iodide and Hydrogen Peroxide, using initial velocity and activation energy calculation, this paper proposes and discusses the reaction mechanism in the reaction.

通过改进碘化钾与过氧化氢的反应实验,用初速度的方法,通过活化能的计算,讨论提出的反应机理,确定反应级数和催化反应与非催化反应的速度常数。

The additional activity of the mechanical mixture can be ascribed to the acid sites on dealuminated Y zeolite, where the activated hydrogen spilt over from the neighboring Pt sites could hydrogenate the adsorbed benzene with the formation of cyclohexane and methylcycloheptane.

发现虽然Y沸石本身没有加氢活性,但它的加入可以显著提高Pt/Al2O3的活性,因为在Pt中心上得到活化的氢可以快速溢流到邻近的沸石颗粒表面的酸中心上,并和吸附在其上的苯发生加氢反应生成环己烷和甲基环戊烷。

A kinetic model of fat and oil hydrogenation is given in this paper.

给出了油脂氢化反应中活化态氢与甘三酯分子反应的动力学模型。

The role of gold is to activate molecular oxygen and promote the decomposition of cyclohexyl hydroperoxide to target products, accounting for the high activity and selectivity of gold catalysts in cyclohexane oxidation.

金在环己烷氧化过程中的作用主要表现为活化分子氧,同时促进中间产物环己基过氧化氢分解为目标产物,从而表现出较高的活性和选择性。

Results indicate that the activated silica and powdered coal ash are both good for hydrophobia dyes, but for active dyes or diazo-dyes are not ideal.

试验结果表明,活化后的硅藻土和粉煤灰对疏水性染料效果良好,而对活性染料或偶氮染料效果不够理想。

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推荐网络例句

I am accused of being overreligious," she said in her quiet, frank manner,"but that does not prevent me thinking the children very cruel who obstinately commit such suicide.""

客人们在卡罗利娜·埃凯家里,举止就文雅一些,因为卡罗利娜的母亲治家很严厉。

Designed by French fashion house Herm è s, this elegant uniform was manufactured in our home, Hong Kong, and was the first without a hat.

由著名品牌 Herm è s 设计,这件高贵的制服是香港本土制造,是我们第一套不配帽子的制服。

Do not 'inflate' your achievements and/or qualifications or skills .

不要 '夸大' 你的业绩或成果,条件或者技能。