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Dimeric structure and several signaling pathways have thus far been proved to be closely correlated with the activation of c-Kit.

迄今为止,二聚化结构及磷酯酰肌醇3′-激酶(PI3K)、JAK-STAT等十几条激酶介导的信号通路被陆续证实与c-Kit的活化密切相关,而针对抑制c-Kit活化设计的靶向药物也陆续投入应用,与特异性的单克隆抗体一起在临床相关肿瘤的诊断及治疗等方面起到了关键性的作用。

A previous positron emission tomography study found that smelling AND and EST activated regions covering sexually dimorphic nuclei of the hypothalamus, and that this activation was differentiated with respect to sex and compound.

在先前的正子断层造影研究发现男性受试者闻到EST时,在下视丘有明显活化反应,女性受试者闻到AND时,在下视丘有明显活化反应。

Based on the development of homogeneous gold complex catalyst, the polymer immobilized nano-gold catalyst was also prepared and used for oxidative carbonylation of amines or activation of carbon dioxide to carbamates and disubstituted ureas without addition of any co-catalyst and dehydration agents with greatly enhanced catalytic activity (TOF≈3000mol/mol/h).

同时,纳米金可以催化活化二氧化碳与脂肪族胺反应制备二取代脲,避免了传统上二氧化碳活化所大量使用的脱水剂,是当前文献报道最高效的胺与二氧化碳反应的催化剂体系(TOF≈3000mol/mol/h)。

The activation of glia in the spinal cord was one important reason of the change in substance P excreted from cornu dorsale medullae spinalis. Inhibitor of glia activation will be a new way to treat CP/CPPS.

胶质细胞活化是CP/CPPS大鼠脊髓背角P物质变化的重要原因,胶质细胞活化抑制剂的应用将是治疗CP/CPPS的新亮点。

Our within-subject analysis also showed activation of brain areas associated with negative emotions, including right insula and putamen (11, 38), during the high-stress relative to the low-stress task. The observed activation in the dorsomedial prefrontal cortex ACC and precuneus parietal cortex may ref lect mental arithmetical performance (39) and assessment of the mental state (40) during the serial-subtraction task, whereas the CBF reduction in pre- and postcentral gyri and temporal cortex may ref lect more frequent verbal movement and greater auditory stimulation during counting backward versus serial subtraction.

我们的在之内主题分析也显示了脑子区域的活化作用与消极情感相关,包括正确的脑岛并且putamen (11, 38),在期间高注重相对低注重任务在连续减法任务期间,被观察的活化作用在dorsomedial前头叶外皮ACC和precuneus头顶骨外皮可以ref lect精神算术对精神状态(40)的表现(39)和评估,而CBF减少前和中央后回和世俗外皮可以ref lect更加频繁的口头运动和更加伟大的听觉刺激在计数期间落后对连续减法。

The Ea for the formation of ethoxide intermediate was 170.34 kJ/mol. Alkylation of benzene with ethylene occurred through both concerted mechanism and stepwise mechanism, and they were competitive to each other. These two paths were only slightly different in the activation energy.

而乙烯作为烷基化剂与苯反应时同时存在联合机理和分步机理,且二者之间存在一定程度的竞争,其中联合机理的活化能为167.24 kJ/mol,分步机理速控步骤的活化能为155.20 kJ/mol。

It has been found from inspection that the main causes leading to somewhat larger electric current of said induced draft fan are as follows;(1) Top corrosion in outlet flue duct of the activator;(2) Fallaway of guide plates in outlet of the activator;(3) Air leakagein due to wornout of the flue duct .

检查发现活化器出口烟道顶部腐蚀、活化器出口导流板脱落、烟道磨损漏风是导致2号锅炉引风机电机电流偏大的主要原因。

METHODS: A model of T cell activation and proliferation was established by stimulated the cells with Con A.T cells were treated with different concentrations of CPT. The expression of CD69, the early marker of CD3(superscript +) T cell activation, was measured by FACS. The proliferation index was determined by carboxyl fluorescin diacetate succinmidyl ester by flow cytometry. The cell-cycle distribution was analyzed by propidium iodide staining.

以ConA刺激小鼠T淋巴细胞,建立小鼠T淋巴细胞活化、增殖的模型,以不同浓度的CPT作用于该模型,流式细胞术检测T细胞早期活化标志CD69分子的表达;以活体染料羧基荧光素乙酰乙酸染色流式细胞术分析CPT在ConA刺激下小鼠淋巴细胞的增殖相关指数;以碘化丙啶染色流式细胞术分析细胞周期的分布情况。

METHODS: After stimulated with Con A, T cells were treated with different concentrations of TMB-8 alone and its combination with cyclosporine A. The expression of CD69, the early marker of CD3(superscript +) T cell activation, was measured by FACS. The proliferation-related index was determined by carboxyl fluorescin diacetate succinmidyl ester flow cytometry. The cell-cycle distribution was analyzed by propidium iodide staining.

以Con A作为T细胞活化、增殖的刺激剂,以不同浓度的TMB-8及与环孢菌素A联合作用于该系统,用流式细胞术检测T细胞早期活化标志CD69分子的表达;以活体染料羧基荧光素乙酰乙酸染色流式细胞术,分析TMB-8在Con A刺激下小鼠淋巴细胞的增殖相关指数;以碘化丙啶染色分析细胞周期的分布情况。

Fundic mast cell and H.Pylori infectious status may have no effect on proximalstomach function.

胃底肥大细胞计数、活化数及活化率以及H.pylori感染情况可能与近端胃功能障碍无关。

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With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务,乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐,因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。

Closes the eye, the deep breathing, all no longer are the dreams as if......

关闭眼睛,深呼吸,一切不再是梦想,犹如。。。。。。