活动过度的

Repeated minor trauma and overuse play an important role for the development of lesions in Hoffa's pad, extensor mechanism, lateral and medial restrain structures or cartilage surface, however usually an increase or change of activity is referred.

反复的微创伤和过度使用膝关节在膝关节的以下病损的发生中起到重要作用：Hoffa氏脂肪垫、膝关节伸膝装置、膝关节内侧和外侧限制结构或软骨表面，然而，活动的增加或改变常常为诱发因素。

Ultimately, vulnerable groups of neurons atrophy and die in a process that may involve excitotoxicity (overstimulation of neurotransmitter receptors on neuronal surface membranes), collapse of calcium homeostasis, inflammation, and depletion of energy and growth factors.

最终在兴奋性毒性（过度刺激神经元上的递质受体）、钙紊乱、炎症、能量和生长因子缺乏作用下，敏感的神经元发生萎缩、死亡。apoE4与Aβ和tau的异常聚集有关，还可能损伤线粒体和其他细胞骨架。Aβ、tau、apoE和synuclein与其他分子相互作用，影响多种神经活动和存活的信号转导途径。

Ultimately, vulnerable groups of neurons atrophy and die in a process that may involve excitotoxicity (overstimulation of neurotransmitter receptors on neuronal surface membranes), collapse of calcium homeostasis, inflammation, and depletion of energy and growth factors. A form of apolipoprotein E, apoE4, contributes to the abnormal accumulation of A and tau, but probably also damages mitochondria and the cellular cytoskeleton. A , tau, apoE and -synuclein interact with many other molecules and modulate diverse signalling cascades that regulate neuronal activity and survival.

最后，易感神经元会萎缩直至死亡，原因可能有兴奋性中毒（神经递质对神经元表面受体的过度刺激引起），钙稳态失衡，炎症反应，能量和生长因子的耗尽。apoE4的产生可导致A肽和tau蛋白的异常聚合，可能也损害线粒体和细胞骨架。A肽、tau蛋白、apoE和突触核蛋白可与很多分子反应，也可调节不同信号级联反应，这些级联反应对于维持神经元活动性和生存性意义重大。

Some conclusions from the study on human driving factor are:(1) the human activity is much more active factor to the process of desertification which mainly incarnates on the changes of the landuse fashion (from traditional rangeland 100 years ago come to interlacing agro-pastoral region) and enhance of landuse intensity (over-cultivation, over-grassing and over-fuel collection);(2) the natural vegetation had been destroyed suicidally by human activities that had accelerated to the development desertification.

在人为驱动力的分析中，得到以下一些初步的结论：（1）人类活动是本地区沙漠化过程中更加活跃的驱动因子，体现在土地利用方式的转变（从传统的牧业草原到今日的农牧交错区）和强度的增加（过度开垦、放牧、樵采等）；（2）由此对自然植被群落毁灭性的破坏，加速沙漠化的进程。

Considering electroencephalography as summed activity of few neuroelectric generators in the brain, the epileptogenic spike can be assumed as the over discharge of one or multiple generators.

中文摘要一般而言，可将脑波视为数个脑部发动器活动的总和，而癫痫性棘波的产生可假设为脑部一个或多个焦点的过度放电；而所谓脑波图的时空特性，则是探讨此棘波的空间位置以及随时间之变化情形。

The evidences from neuroanatomy, neurophysiology, especially recently from neuropsychology and neuroimaging studies of OCD suggest that: the functional overactivities in OFC and ACC could be responsible for the increased functions of error recognition and evaluation of emotion and motivation; the functional hypoactivity in DLPC could result in the lack of cognitive integration of the consequence of action.

来自神经解剖、神经生理以及近期神经心理和功能成像等的相关研究证据显示：OCD病人眶额皮层、前扣带回皮层的过度激活可能会导致错误识别功能和对行为结果预期的情绪与动机评价增高；背外侧前额皮层的活动减弱损害了对信息加工的认知整合能力。

Traditionally taping as most often seen on television is done on athletes. For them the use of these tapes are usually to stop an injury from worsening itself during sports. For athletes without injury, or has already completely healed, it maybe used as prophylactically .

很久以前，肌肉贴布治疗法主要用在运动员身上，以防止伤患在运动中恶化，它的作用包括：减轻筋膜及肌肉的疼痛、避免肌肉过度伸展及收缩，防止肌肉及关节的受伤及支持肌肉活动等。

International contributors review the current understanding of the biology and cellular mechanisms along with relevant research so you can easily apply them to the pathophysiology of the numerous disorders that botulinum toxin is used to treat—such as botulinum toxin applications for the treatment of cranial-cervical dystonias, motor disorders in cerebral palsy, bruxism and temporomandibular disorders, headache, overactive bladder, chronic pelvic pain syndromes, arthritis joint pain, and wound healing.

编写本书的几位国际专家回顾了当前对生物学和细胞机制的认识及相关研究，便于读者了解那些应用肉毒毒素治疗的许多疾病的病理生理学——如应用肉毒毒素治疗治疗头颈部肌张力障碍、脑瘫运动障碍、磨牙症和颞下颌关节紊乱病、头痛、膀胱过度活动症、慢性盆腔疼痛综合征、关节炎关节疼痛和创口愈合。

Combination of high-strength composite resin with titanium to make fixed or removable partial denture had many advantages.

硬质复合树脂与钛联合使用制作固定或活动义齿，既可以利用钛生物相容性好、机械强度高、比重小的优点，避免其它非贵齿科合金(Co-Cr、Ni-Cr合金)的潜在生物毒性；又可以避免烤瓷硬度过大对对牙合牙的过度磨耗以及崩瓷后不易修复的缺点。

Indicators of autism include oversensitivity or under reactivity to touch, movement, sights, or sounds; physical clumsiness or carelessness; poor body awareness; a tendency to be easily distracted; impulsive physical or verbal behavior; an activity level that is unusually high or low; not unwinding or calming oneself; difficulty learning new movements; difficulty in making transitions from one situation to another; social and/or emotional problems; delays in speech , language or motor skills ; specific learning difficulties/delays in academic achievement.

自闭症指标包括过度反应或触摸、运动、观光、或听；身体迟钝或疏忽；身体意识差；容易分心的倾向；冲动身体或言语行为；一个活动的水平高低，是不寻常；不缓，镇静自己；难新动作的学习；难以进行交接，由另一种情况；社会和/或情绪问题；延误讲话，语言或运动技能；读写困难/延误学术成就。

I am accused of being overreligious," she said in her quiet, frank manner,"but that does not prevent me thinking the children very cruel who obstinately commit such suicide.""

客人们在卡罗利娜·埃凯家里，举止就文雅一些，因为卡罗利娜的母亲治家很严厉。

Designed by French fashion house Herm è s, this elegant uniform was manufactured in our home, Hong Kong, and was the first without a hat.

由著名品牌 Herm è s 设计，这件高贵的制服是香港本土制造，是我们第一套不配帽子的制服。