活动过度

"This implies in particular the need for a clearly defined public service mission as well as a limitation of state aid to what is necessary for the fulfilment of this mission, excluding overcompensation and possible cross-subsidies into commercial activities," it said.

这意味著，它特别需要对公共服务的使命有明确的定义，以及限制国家的援助，这些都是为了完成这一个使命，但是并不包括过度地补偿和交叉补贴公共服务广播，而让它变为商业活动。

The O stands for overexertion. Avoid activities that will make you sweaty.

字母O代表"过度地用力"，要避免那些易出汗的活动。

Ultimately, vulnerable groups of neurons atrophy and die in a process that may involve excitotoxicity (overstimulation of neurotransmitter receptors on neuronal surface membranes), collapse of calcium homeostasis, inflammation, and depletion of energy and growth factors.

最终在兴奋性毒性（过度刺激神经元上的递质受体）、钙紊乱、炎症、能量和生长因子缺乏作用下，敏感的神经元发生萎缩、死亡。apoE4与Aβ和tau的异常聚集有关，还可能损伤线粒体和其他细胞骨架。Aβ、tau、apoE和synuclein与其他分子相互作用，影响多种神经活动和存活的信号转导途径。

Ultimately, vulnerable groups of neurons atrophy and die in a process that may involve excitotoxicity (overstimulation of neurotransmitter receptors on neuronal surface membranes), collapse of calcium homeostasis, inflammation, and depletion of energy and growth factors. A form of apolipoprotein E, apoE4, contributes to the abnormal accumulation of A and tau, but probably also damages mitochondria and the cellular cytoskeleton. A , tau, apoE and -synuclein interact with many other molecules and modulate diverse signalling cascades that regulate neuronal activity and survival.

最后，易感神经元会萎缩直至死亡，原因可能有兴奋性中毒（神经递质对神经元表面受体的过度刺激引起），钙稳态失衡，炎症反应，能量和生长因子的耗尽。apoE4的产生可导致A肽和tau蛋白的异常聚合，可能也损害线粒体和细胞骨架。A肽、tau蛋白、apoE和突触核蛋白可与很多分子反应，也可调节不同信号级联反应，这些级联反应对于维持神经元活动性和生存性意义重大。

Even with the effort to limit the demands upon his time, there were fears that Mandela would be overtaxed.

尽管对曼德拉的活动时间安排已尽量作了限制，人们仍然担心他会劳累过度。

Malfunction will result in cystic fibrosis, chronic pancreatitis, male sterility, habitual constipation, keratoconjunctivitis sicca (KCS, also called dry eye syndrome). Over activation of CFTR is related to diarrhea, polycystic kidney disease.

该通道活动的异常与多种疾病的病理发生相关：CFTR氯离子通道功能丧失或活性降低可导致慢性胰腺炎、多囊肾病、男性不育、习惯性便秘和干眼病等；而功能的过度激活则可导致分泌性腹泻、多囊肾病等。

If your thyroid gland is under active or overactive, you will suffer the problem of hair loss.

如果你的甲状腺正在积极或过度活动，您将受到这个问题的脱发。

Some conclusions from the study on human driving factor are:(1) the human activity is much more active factor to the process of desertification which mainly incarnates on the changes of the landuse fashion (from traditional rangeland 100 years ago come to interlacing agro-pastoral region) and enhance of landuse intensity (over-cultivation, over-grassing and over-fuel collection);(2) the natural vegetation had been destroyed suicidally by human activities that had accelerated to the development desertification.

在人为驱动力的分析中，得到以下一些初步的结论：（1）人类活动是本地区沙漠化过程中更加活跃的驱动因子，体现在土地利用方式的转变（从传统的牧业草原到今日的农牧交错区）和强度的增加（过度开垦、放牧、樵采等）；（2）由此对自然植被群落毁灭性的破坏，加速沙漠化的进程。

There are four characters that can be found in this process. Firstly, it is a struggle within the political system. In other words, tenants admit the hierarchical rights of ruling class, but reject excess exploit. Secondly, the resistance has various ways, and law is a frequent resort too. Thirdly, collective resistance comes to be the most common form, wealthy peasants always act as organizers and leaders. Fourthly, tenants' resistance processes exhibits obvious different theme of demands in all phrases. Before mid and latter of 14 century, most requirements aim to reject duty beyond custom; while after, mainly to strive for cutting down the rents and tallage.

再次，文章分析了英格兰佃农抗争的四个特点，一是体制内的抗争，即佃农接受统治阶级的等级权利，反抗过度剥削；二是抗争方式多法并举，以法律手段为主；三是集体抗争逐渐成为抗争的主要组织形式，富裕佃农是抗争活动的组织者和领导者；四是抗争历程有着鲜明的时代主题，即以14世纪中后期为界，之前以抵抗领主超出惯例规定的要求为主，之后以争取减免地租捐税为主。

Objective To evaluate the efficacy and tolerability of tolterodine in patients with an overactive bladder.

目的 评价新型抗胆碱药物托特罗定治疗膀胱过度活动症的有效性和安全性。

Lugalbanda was a god and shepherd king of Uruk where he was worshipped for over a thousand years.

Lugalbanda 是神和被崇拜了一千年多 Uruk古埃及喜克索王朝国王。

I am coming just now,' and went on perfuming himself with Hunut, then he came and sat.

我来只是现在，'歼灭战perfuming自己与胡努特，那麼，他来到和SAT 。