泻

This paper is mainly comprised of two components:preparation of models of rats suffering from deficiency of spleen Yang;comparison of the pharmacodynamics impacts of different Lizhong Pills formulations made up by dried ginger or its different components in Lizhong Pills to the different groups of the models.1 Establish the model of deficiency of spleen YANG induced by " cypsum fibrosum and anemarrhenae " with complex factors1.1 ObjectivesWith using heat-clearing and fire-purging drug cypsum fibrosum and anemarrhenae,insteading of the common usage of rhubarb and folium sennae,accompanied with irregular diet and overstrained,the model of deficiency of spleen-YANG is to be established,which is much close to the pathopoiesis theory of " frigidity and chilly damaging yang,irregular diet injuring qi,overstrain impairing the spleen" in TCM.1.2 MethodsModel rats is fully fed every other day,given the molding drug of cypsum fibrosum -anemarrhenae(concentration 4:1) with 3 different frequency,and arranged to swim everyday in 25℃water until exhausted(performing as spitting bubble 3 times continuously or sinking unable to float by itself).

全文共分为脾阳虚模型的制备和干姜及其成分对理中丸药效学影响的比较两大部分。1"石膏-知母"复合法脾阳虚模型的制备1.1目的以清热泻火药石膏-知母代替常用的大黄、番泻叶类苦寒泻下药，并结合饥饱失常、劳倦过度的方法进行造模，以期建立更符合中医"寒凉伤阳、饥饱伤气和劳倦伤脾"致病思路的中医脾阳虚证候模型。1.2方法模型动物隔日足量喂食，每日在25℃水中游泳，直至大鼠连续三次吐泡下沉，或沉入水底，3秒内不能自行浮出水面，并以三种不同给药频率灌胃给予石膏一知母煎液，比较石膏-知母不同给药方法对制备脾阳虚模型的影响。

But only partial changes of rhubarb laxation group and over-swimming group have a coherent trend to those of SAS clinical patents. Our improved over-fatigue method is better than rhubarb laxation method and over-swimming method. Proved by Sijunzi decoction treatment, the mice behave normally. All objective indexes are improved more distinctively than the group that resumes naturally. These prove that the SAS model is made successfully and meets the requirements of judgement for SAS animal model. In this model, SAS is caused possibly by largely released Gas, which results in increased contractile in small intestine, over-exudation of intestine and obstacle in absorption.

在所选的指标中，改良型劳倦过度组小鼠的变化均与临床脾虚证患者的变化趋势一致，且多数指标的变化较大黄组(大黄泻下法塑造脾虚证动物模型)和力竭游泳组(力竭游泳法塑造脾虚证动物模型)明显，而大黄组和力竭游泳组只有部分指标的变化与临床患者一致，因此，改良型劳倦过度法塑造脾虚证动物模型优于大黄泻下法和力竭游泳法。

A series of factors such as observation index (mass of feces in 10 hours), animal strain, sex and the dose of diphenoxylate complex (50 mg·kg-1) was investigated and fixed.

以大黄泻下活性的量效关系、数据变异程度以及实验的可操作性为考察指标，筛选并确定了大黄致泻效价测定模型的观测指标(10 h内排便量)、动物品系、性别、便秘模型造模剂用量(复方地芬诺酯50 mg·kg-1)等实验条件。

After the normal degermation of acupoints,the points of double LI20 with needles of 1cun is punctured, directing the needles on double LI20 to nasion, even reforcing and reducing after developing needle sensation, and be sure to make needle sensation into nasal cavity;puncture DU23 with the needle of 1cun,directing the needle to forehead ,twirling and rotating until the generation of needle sensation;puncture perpendicularly double LI4 with the needle of 1.5 cun, reforcing and reducing after developing needle sensation, manipulating every 10 minutes;puncture perpendicularly double St36 with needle of 1.5cun,reforcing by lifting, thrusting ,twirling and rotating after developing needle sensation.

针取30号毫针。穴位常规消毒后，用1寸毫针针刺双迎香，针尖朝向鼻根部，得气后行平补平泻法，针感传达至鼻腔中；上星用1寸毫针针刺，针尖朝向前额部，快速捻转，以产生针感为度；以1.5寸毫针直刺双合谷，得气后行平补平泻法，以上三穴每10 min捻针一次，留针30min；以1.5寸毫针直刺足三里，得气后行提插捻转补法，留针30 min。

Objective To determine the contents of rhein and sennoside A in extracts of rhubarb prepared with microwave extraction .

目的 建立大黄微波提取物中大黄酸、番泻苷A两种泻下成分的含量测定方法。

ABSTRACT AIM: To study the antidiarrheic effect of domestic smectite on diarrhea in mice induced by senna.

目的：研究国产蒙脱石对番泻叶引起的小鼠腹泻的止泻作用和对结肠炎症的抑制作用。

Were studied in the mice which were given high concentration of powdered milk solution to induced supernutrition, and the effects of these drugs on the activity of pepsin were measured in vitro. The effect of milk on the lapactic action of anthraquinon and glycosides of anthraquinone were analyzed using the factorial design. ResultsThe anthraquinone of Rheum palmatum L.

方法通过灌服高浓度的奶粉溶液以营造高营养性环境，在此基础上考察了大黄结合蒽醌及游离蒽醌对小鼠的致泻作用；并运用析因设计分析了奶粉在这些致泻作用中的作用，同时还考察了大黄结合蒽醌及其游离蒽醌体外对胃蛋白酶活性的影响。

In mice. MethodsThe lapactic effects of anthraquinon and glycosides of anthraquinone from Rheum Palmatum L. were studied in the mice which were given high concentration of powdered milk solution to induced supernutrition, and the effects of these drugs on the activity of pepsin were measured in vitro. The effect of milk on the lapactic action of anthraquinon and glycosides of anthraquinone were analyzed using the factorial design.

通过灌服高浓度的奶粉溶液以营造高营养性环境，在此基础上考察了大黄结合蒽醌及游离蒽醌对小鼠的致泻作用；并运用析因设计分析了奶粉在这些致泻作用中的作用，同时还考察了大黄结合蒽醌及其游离蒽醌体外对胃蛋白酶活性的影响。

Methods The effect of Magnolol on the propulsion of carbo medicinalis in small intestine in the mice given Rhubarb was observed.

观察厚朴酚对生大黄小鼠小肠炭末推进的影响及对番泻叶与蓖麻油引起小鼠腹泻模型的止泻作用。

The model of thyroid hormone-induced diarrheic rats was prepared and interfered by low, medium and high dose of Asi-antidiarrheal capsule and berberine. Immunohistochemistry was used to detect the population, ratio of degranulation, area, perimeter, equivalent diameter and cyclo-dimension of the MC in duodenum mucosa of control group, model group, berberine group and Asi-antidiarrheal capsule group.

运用阿是止泻胶囊低、中、高剂量及黄连素对其干预，采用免疫组化技术测定对照组、模型组、黄连素组、阿是止泻胶囊低、中、高剂量组大鼠十二指肠黏膜MC数量、脱颗粒比率、面积、周长、等效直径及圆形度。

The absorption and distribution of chromium were studied in ryeusing nutrient culture technique and pot experiment.

采用不同浓度K2CrO4(0，0.4，0.8和1.2 mmol/L)的Hoagland营养液处理黑麦幼苗，测定铬在黑麦体内的亚细胞分布、铬化学形态及不同部位的积累。

By analyzing theory foundation of mathematical morphology in the digital image processing, researching morphology arithmetic of the binary Image, discussing two basic forms for the least structure element: dilation and erosion.

通过分析数学形态学在图像中的理论基础，研究二值图像的形态分析算法，探讨最小结构元素的两种基本形态：膨胀和腐蚀；分析了数学形态学复杂算法的基本原理，把数学形态学的部分并行处理理念引入到家实际应用中。