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The mice inoculated with Coxiella burnetii intrana- sally developed interstitial pneumonia,while the primary pathological changes of mice inoculated intraperitoneally are granulomas in spleen and liver.2.The pathological changes became more severe followed the dosage increasing.3.Coxiella burnetii can be detected in spleen and liver at day 2 after inoculation.the lesion became more and more serious from day 2 to day 12.The characteristic changes were observed at day 7,and recovered at day 14. 4.The reticuloendothelial system are main target of Coxiella burnetii.The pathogen was detected in cytoplasm of monocyte -macrophages of spleen, liver, lung, and endothelioid cells of blood vessel. 5. Coxiella burnetii can be found in macrophages lysosomes by electron microscopy. Most of them are round or rod, and polymorphic shape can also be observed in different size.

结果:1、通过不同感染途径的实验证实,滴鼻感染的小鼠主要表现为间质性肺炎,而腹腔注射感染小鼠则以脾脏、肝脏肉芽肿为主要病变。2、通过不同剂量的感染实验发现,随着感染Q热立克次体剂量的加大,动物病变愈加严重。3、通过感染后不同时间的动态病理学观察发现,在腹腔注射后第2d的脾和肝脏即可发现病原体,主要脏器的病理变化从第2d到第12d逐渐加重,第7d动物的病变最典型,至感染后14d动物的受损器官已开始出现修复性变化。4、 Q热立克次体主要侵害机体的网状内皮系统,在感染小鼠的肝、脾、肺和外周血管单核巨噬细胞以及血管内皮细胞胞浆中查见病原体。5、透射电镜观察可见Q热立克次体主要位于巨噬细胞吞噬溶酶体内,呈多形性,多见圆形和杆状,大小不一。

Methods The chronic ocular hypertention rat model was made by cauterizating three episcleral veins.Rats were divided into control group,high level PROG group,middle level PROG group,low level PROG group according to different concentrations of PROG injected intraperitoneally.The left eye was model eye and the right eye was control eye.Three months later,the animals were executed and the eyeballs were enucleated.The RGCs were detected by HE staining and Thy-1.1 immunohistological staining.

通过烧灼3条巩膜上静脉制作慢性高眼压动物模型,此模型按腹腔注射不同浓度的孕酮而分为高、中、低浓度孕酮注射组及空白对照组,左眼为模型眼,右眼为自身对照眼,3个月后处死动物,取眼球制石蜡切片,行HE染色、Thy-1.1免疫组化染色及TUNEL原位凋亡检测。

Kopin et al, estimate that exogenously administered melatonin disappears from whole mice with a half-life of about 2 min through the first 10 min following injection but that after 40 min the half-life has grown to about 35 min.

Kopin等人,估计外部褪黑素从整个小鼠消失的半衰期在注射后的最初10分钟里,大约为2分钟,但注射后40分钟后半衰期就增长到约35分钟。

RESULTS: Injection of the solution of tissue plasminogen activator into anterior chamber of 15 eyes resulted in complete dissolution of the fibrinous membranes in 9 (60.0﹪)eyes after 2 hours, and 11 (73.3﹪) eyes within 1 day.

结果:在前房注射tPA的1 5眼中,其中9眼(60.0﹪)在2h后纤维蛋白膜完全溶解,11眼(73.3﹪)在1d内完全溶解。3眼内注射tPA几天后纤维蛋白膜复发。

Hepatic artery infusion chemotherapy is used primarily in patients with inoperable primary or metastatic hepatic tumors. During HAIC system implantation, the guide wire used to support the insertion of the catheter can damage the gastroepiploic artery resulting in intraperitoneal bleeding when percutaneous catheter placement and tip fixation method was used.

肝动脉化疗经常是用在无法开刀的原发性或转移性恶性肝肿瘤的治疗方法,而在肝动脉化疗导管暨注射基座系统植入时经常将导线置於胃大网膜动脉来做为支撑导管置入的路径,所以在肝动脉化疗导管暨注射基座系统植入过程中胃大网膜动脉可能会受到损害而有可能导致腹内之出血。

After single dose administration of insulin Glar 1/3 of subjects did not have an onset of action (defined as 50% reduction of the regular i.v. insulin from clamp onset to maintain euglycemia) within 10 hours after insulin injection.

单次剂量注射后Glar组1/3的受试者胰岛素在注射10小时内失效(定义为钳夹试验中为维持正常血糖,静脉输注常规胰岛素剂量减少50%)。

Objective To research the curative effect of autogenous fat injection laryngoplasty for patients with glottal dysraphism hoarseness.

目的探讨自体脂肪声带注射治疗声门闭合不全性声嘶的疗效。方法对32例不同病因所致声门闭合不全性声嘶患者,采用支撑喉镜下自体脂肪声带注射的方法进行治疗。

BACKGROUND: Glottic insufficiency can be corrected with injection laryngoplasty. Up to the present, a perfect injectable substance has not been identified. Thus, an improved injectable substance is needed.

注射喉整形术可以用来治疗不同声带疾病所产生的声门闭合不全,目前没有一种注射用的材料是尽善尽美的,我们仍试图找寻更好的材料。

Combination of intraarticular injection of hyaluronate and pain-point injection of betamethasone can effectively relieve the pain symptom of osseous gonarthritis, with no obvious adverse reactions.

玻璃酸钠关节腔内注射联合倍他米松痛点注射可有效缓解骨性膝关节炎的疼痛症状,且无明显不良反应发生。

ABSTRACT Objective: In order to study the mechanism of guttatim epidural injection , the experiment was designed to research into the digestion of collagens of nucleus after injection and the relationship between the rate of injection and the dose level of collagenase.

上海第二医科大学附属新华医院伤科,上海 200092 ; 2 上海市伤骨科研究所,现:上海沐阳医院)摘要目的:观察盘外置管法注射胶原酶是否有利于髓核的溶解以及胶原酶的注射剂量与滴速对髓核的溶解是否有影响。

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