注

Abstract］ Objective For the purpose of scientific evaluation and improvement on unreasonable parameter of viral inactivation,the dynamics curve of time corresponding to effect by given viral inactivation factor treated to blood plasma product were analyzed.Methods Aimed at vesicular stomatitis virus, sindbis virus, human immunodeficiency virus, polioviruses, pseudorabies virus,encephalon-yocarditis virus; validate data of viral inactivated on pasteurization of albumin, human rabies immunoglobulin with pH 4, human immunoglobulin and human hepatitis B immunoglobulin for intravenous injection with pH 4/pasteurization,treatment on human fibrinogen and human coagulation factor Ⅷ with solvent/detergent and vapor heating at 100 ℃30 min were systemic regularized respectively.The mean and standard deviation also coefficient of variation for virus survival titer in different time were stated, dynamics curve of virus inactivation were made and analyzed.

目的 分析血液制品特定灭活因子的时效动力学曲线，科学性地评价与改进不合理的病毒灭活参方法系统性整理针对水疱性口炎病毒、黄热病毒、脊髓灰质炎病毒、伪狂犬病毒、脑心肌炎病毒、人类免疫缺陷病毒，人血白蛋白采用巴氏消毒法，狂犬病人免疫球蛋白采用低pH常温孵放法，静注人免疫球蛋白、静注人乙肝免疫球蛋白采用低pH/巴氏消毒法；人纤维蛋白原、人凝血因子Ⅷ采用有机溶剂/去污剂与干热法灭活病毒的验证资料，统计3批样品取样点的残余病毒滴度均值、标准差与变异系数，制作灭活病毒动力曲线图并进行分析。

Abstract］ objective for the purpose of scientific evaluation and improvement on unreasonable parameter of viral inactivation,the dynamics curve of time corresponding to effect by given viral inactivation factor treated to blood plasma product were analyzed.methods aimed at vesicular stomatitis virus, sindbis virus, human immunodeficiency virus, polioviruses, pseudorabies virus,encephalon-yocarditis virus; validate data of viral inactivated on pasteurization of albumin, human rabies immunoglobulin with ph 4, human immunoglobulin and human hepatitis b immunoglobulin for intravenous injection with ph 4/pasteurization,treatment on human fibrinogen and human coagulation factor ⅷ with solvent/detergent and vapor heating at 100 ℃30 min were systemic regularized respectively.the mean and standard deviation also coefficient of variation for virus survival titer in different time were stated, dynamics curve of virus inactivation were made and analyzed.results human albumin pasteurization inactivated vsv and sindbis virus,hrig low ph inactivated vsv and sindbis virus,hrig low ph inactivated hiv virus,ivig low ph/pasteurization inactivated hiv virus,ivig low ph inactivated hiv virus,hbig low ph/pasteurization inactivated vsv,sindbis and polio virus.conclusion suggestion about improvement on unreasonable parameter and standard of virus inactivation is made,cultivate target virus directly from final product by appropriate cell or method to monitoring viral safety of blood plasma product is advanced.

目的 分析血液制品特定灭活因子的时效动力学曲线，科学性地评价与改进不合理的病毒灭活参数。方法系统性整理针对水疱性口炎病毒、黄热病毒、脊髓灰质炎病毒、伪狂犬病毒、脑心肌炎病毒、人类免疫缺陷病毒，人血白蛋白采用巴氏消毒法，狂犬病人免疫球蛋白采用低ph常温孵放法，静注人免疫球蛋白、静注人乙肝免疫球蛋白采用低ph/巴氏消毒法；人纤维蛋白原、人凝血因子ⅷ采用有机溶剂/去污剂与干热法灭活病毒的验证资料，统计3批样品多个取样点的残余病毒滴度均值、标准差与变异系数，制作灭活病毒动力曲线图并进行分析。结果人血白蛋白巴氏灭活vsv与sindbis病毒，hrig低ph灭活vsv和sindbis病毒，hrig低ph灭活hiv病毒，ivig低ph/巴氏灭活hiv病毒，ivig低ph灭活hiv病毒，hbig低ph/巴氏灭活vsv、sindbis与polio病毒。结论建议改进病毒灭活验证标准与不合理的灭活参数；采用终产品样品通过合适细胞或方法直接培养目标病毒来有效监测血液制品的病毒安全性。

Methods Aimed at vesicular stomatitis virus, sindbis virus, human immunodeficiency virus, polioviruses, pseudorabies virus,encephalon-yocarditis virus; validate data of viral inactivated on pasteurization of albumin, human rabies immunoglobulin with pH 4, human immunoglobulin and human hepatitis B immunoglobulin for intravenous injection with pH 4/pasteurization,treatment on human fibrinogen and human coagulation factor Ⅷ with solvent/detergent and vapor heating at 100 ℃30 min were systemic regularized respectively.The mean and standard deviation also coefficient of variation for virus survival titer in different time were stated, dynamics curve of virus inactivation were made and analyzed.

系统性整理针对水疱性口炎病毒、黄热病毒、脊髓灰质炎病毒、伪狂犬病毒、脑心肌炎病毒、人类免疫缺陷病毒，人血白蛋白采用巴氏消毒法，狂犬病人免疫球蛋白采用低pH常温孵放法，静注人免疫球蛋白、静注人乙肝免疫球蛋白采用低pH/巴氏消毒法；人纤维蛋白原、人凝血因子Ⅷ采用有机溶剂/去污剂与干热法灭活病毒的验证资料，统计3批样品多个取样点的残余病毒滴度均值、标准差与变异系数，制作灭活病毒动力曲线图并进行分析。

On the third and succeeding betting rounds, the bets will be raised in specified increments, for instance, two-dollar increments.

关于第三轮和接替投注，投注将会提升指定递增，例如两元递增。

It is the important tool of production among the oil field that the note gathers the pump, its design is qualified to influence the production efficiency of the oil field and production cost directly .

注聚泵是油田中重要的生产工具，说明了液压注聚泵所要解决的主要问题，高效节能，排量可调，液压传动在国民生产各部门占有相当的比重，它的合格与否直接影响到油田的生产效率和生产成本。

The net stake receipts derived from the conduct of authorized betting on football matches by an authorized company.

获批准的公司从举办足球比赛投注所得的净投注金收入徵税。

"Word here but pour that gaze after but hand wield " be that "A Dream in Red Mansions" middle is various narrate to grow once in art judging from content promising fish sets up the bait cause and effect effect have the disheartened line of grass snake on structure effect vanquishing line long distance the integral and indivisible sky is accomplished as for coming up to rectify an article if floating clouds and flowing water the chisel and the vulture adorn the even a tiny bit axe of nothing Shimizu goes out of Seremban just like natural get rid of vulture ornaments But every piece of natural coagulation of thing has become one share trickling sluggishly flow the stream living is natural and aesthetic as well one by one minor livelihood branch has woven into a very dense net the domino.

言在此而意在彼是《红(yan2 zai4 ci3 er2 yi4 zai4 bi3 shi4 _hong2)楼梦》中多种叙事艺术中一种，被脂砚斋喻为&言此而注彼，目送而手挥&，从内容上看有为鱼设饵的因果作用，在结构上有草蛇灰线，伏线。。。言在此而意在彼是《红(yan2 zai4 ci3 er2 yi4 zai4 bi3 shi4 _hong2)楼梦》中多种叙事艺术中一种，被脂砚斋喻为&言此而注彼，目送而手挥&，从内容上看有为鱼设饵的因果作用，在结构上有草蛇灰线，伏线仟里的效果，从整篇文章上来看浑然天成，如行云流水，无丝毫的斧凿与雕饰，宛如清水出芙蓉，天然去雕饰，每一件事情又自然而然的凝结成了一股涓涓流淌的生活流，自然而又唯美，而各个小的生活支流又织成了一张密密麻麻的网，牵一发而动全身。

To pick the depletion region note thick liquid with the traditional use to guard against the fire fighting method to be different,topicked the depletion region to pour into the nitrogen the method topresent more superiority,introduced the motion typecarbon member sieve making nitrogen machine constitution.

与传统的采用向采空区注浆灭火方法不同，向采空区注入氮气的方法呈现出更大的优势，介绍了移动式碳分子筛制氮机的构成、制氮的工艺流程、电气控制以及向采空区注氮在灭火中的优点。

Screw out the oil plug while filling, and screw down as finished.

注油时，将油塞旋下，注油毕，再将油塞旋上拧紧。

Most casing damages in Zhongyuan oilfield take place in the salt bed formations, and this has remained a problem that seriously threatens oil and gas production for long time. Causes of casing damages were investigated, and a series of measures in casing design have been adopted accordingly, but with unsatisfactory results.

中原油田由于地质结构复杂，断层纵横交错，油气埋藏深，又有多套盐膏层覆盖，再加上注采关系不够平衡，导致了一大批先期投产的油水井套损现象十分严重，这不仅造成了巨大的经济损失，而且破坏了注采关系，大幅度地降低了油气产量。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。