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Four aspects of research achievements include:(1)several imaging correction methods and strained estimation methods for biological tissues elasticity imaging were investigated as well as elasticity reconstruction and phantom, in vitro and in vivo elasticity imaging experiments;(2)in the fields of biological microsystem and perfusion evaluation for microvascular system, three kinds of microbubbles whose shell are albumin, sugar ester and surfactant respectively were designed and produced, then the methods to estimate the thickness of their shells were presented, moreover, the interacting mechanism of ultrasound contrast agents and tissues, as well as protein drug delivery under the condition of ultrasound sonification were studied in the molecular level;(3) At the aspect of high intensity focused ultrasound therapy system, we designed and constructed the 256-element HIFU transducers using 1-3 composite materials. And furthermore we developed the integrated HIFU system with 256-element HIFU transducers. And we made preliminary and important progresses in the research of HIFU bioeffect, lesion estimation, techniques of monitoring and imaging and characterizing of structure of HIFU transducer;(4)The real-time method of voice source regeneration based on compensative regulation of physiological parameters was investigated in the field of medical rehabilitation. We addressed the physiology and biophysics of vocalization, modeled voice source regeneration based on compensative regulation mechanism, and put forward an integrated evaluation about the speech rehabilitation and the regenerated voice source; Sixty-one archived journal papers were published, as well as ten in international journals, and eighteen publications were embodied by SCI.

中文摘要：成果包括：（1）在生物组织弹性成像方面，研究了多种图像校正方法和应变估计方法，进行了弹性重构和仿体、离体及在体超声弹性成像实验研究；（2）在生物微系统和微血管血流灌注成像方面，制备了三种不同包膜超声造影微泡，研究了纳米包膜厚度检测与估计方法以及不同纳米包膜造影微泡断裂与药物释放机制，并在分子层次上开展了超声与生物组织相互作用机制以及蛋白质药物超声乳化微囊包裹的研究；（3）在阵列式高强聚焦超声治疗与监控成像技术方面，设计制作了新的HIFU换能器，解决了256阵元单焦点和多焦点合成HIFU治疗系统关键技术问题，并在HIFU生物效应与创伤性评价方法、HIFU过程监控成像技术和薄层复合结构与HIFU 换能器界面特性评价等方面的研究取得了初步而重要的进展，具有重要应用前景；（4）在语音听觉系统特别是嗓音康复方面，研究了基于发声系统补偿调节机制的实时多模式嗓音源再生方法和发声生理，建立基于神经、肌肉和空气动力系统的综合补偿调节模型，提出了相应的评价系统。

Recombinant hFSH at a dose of 100 IU on alternate days the spermatogenetic process as evaluated by testicular cytologic analysis and an increase in the number of ejaculated sperm and inhibin B secretion.

此次随机单盲研究中，45位先天性低精子数量（0 x 106/mL），并且血浆卵滤泡刺激素与抑制素B浓度较低的男性患者，接受为期三个月的重组人卵滤泡刺激素50 IU或者100 IU隔日治疗，或者不采用任何治疗措施。

During the wall thickening, the number of Golgi bodies increased apparently and cytoplasm was filled with Golgi vesicles. Polylamellate structure of the secondary wall appeard, Along with the further development of tracheary elements, the nucleous disappeared and organelles were decreased, while cortical microtubules were arranged neatly against the inner side of plasmalemma.

初生壁与质膜之间有间隔较规律的次生壁突起；中期，线粒体和高尔基体的数量明显增加，细胞质中几乎充满高尔基体及其囊泡，次生壁中微纤丝已成有序排列；晚期，细胞核消失，导管中央形成空腔，细胞器迅速减少，仅观察到少量高尔基体和线粒体，有大量周质微管沿细胞长轴分布，且在次生壁的周围有大量小泡附着，次生壁的分层结构清晰可见。

The effect of reversible bullouskeratopathy treated with fresh amniotic membrane transplantation is certain, but unreversible bullouskeratopathy not certain.

羊膜移植术为治疗可逆性大泡性角膜病变的有效方法，治疗不可逆大泡性角膜病变效果差。

However, this was not his most severe criticism, which he reserved for theories or theses so unclearly presented as to be untestable or unevaluatable, and thus not properly belonging within the realm of science, even though posing as such.

二一次，在后来发现反质子的意大利物理学家塞格雷做完一个报告和泡利等离开会议室时，泡利对他说：&我从来没有听过像你这么糟糕的报告。&

Under electron microscope, vacuolate degeneration of neuronal processes with mitochondria degeneration and accumulation of microtubule near vacuolar nucleus were observed in iron treated rats.

电镜下可见铁处理大鼠神经突起空泡变性，空泡化的细胞核周线粒体变性及微管堆积。

On the basis of vacuolated toxicity, HP strains were divided into two groups, HP and HP.

据此将HP分为有空泡毒作用的HP及没有空泡毒作用的HP。

However, under electron microscope, lead acetate induced nuclear pyknosis, mitochondrial swelling and vacuolization, and cell blebbing.

但电子显微镜下已出现细胞核固缩；线粒体肿胀、正常结构消失并伴有空泡化；胞内出现鼓泡等现象。

Results Using different concentrations of 5fluorouracil to deal with A549 cells, with the increase in drug concentration and treatment time,cell survival rate decreased significantly;and low concentration of 5fluorouracil induced the cell spread and increased vacuolization within the cytoplasm, acridine orange staining showed an increase in acidic vesicles,high concentration made the cell round and cell apoptosis.

结果不同浓度的5氟尿嘧啶处理A549细胞，随着药物浓度的增加和处理时间的延长，细胞存活率明显下降；且低浓度使细胞呈铺展状态，细胞质内空泡增多，吖啶橙染色显示酸性膜泡增多，高浓度使细胞变圆，出现凋亡状态。

However, under the electron microscope, lead acetate induced nuclear pyknosis, mitochondrial swelling and vacuolization, and cell blebbing were observed.

但电子显微镜下已出现细胞核固缩；线粒体肿胀、正常结构消失并伴有空泡化；胞内出现鼓泡等现象。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。