治疗药

Methods］ninety femal sd rats,weight 230～280 gram,were rangdonmized into three groups: qiangguyin group,miacalcic group and control group.all rats were variectomized.after 10 weeks,the osteoporosis model succeed,the treatment group,contrast group were given qiangguyin,miacalcic respectively.the treatment group used qiangguyin everyday,1ml/g.the contrast group used miacalcic 0.72u/kg,everyday hyodermic.and 3,4.5,6 months after the treatment,kill 10 rats to explore.the neck of femur were cut and stined with masson golder trichrome for bone histomorphomemetric contrast group analysis.

方法］健康雌性sd大鼠90只，体重230～280g。随机分为3组，分别为治疗组、对照组和空白组，每组30只。分别采取切除双侧卵巢方法进行骨质疏松造模，10周造模成功后，开始给药，治疗组用自拟强骨饮灌胃，每日一次，每次1ml/g，对照组用密盖息，皮下注射，每日1次，每次0.72u/kg。空白组，不做处理。在给药后3、4.5、6个月每组各取10只大鼠进行检测，先测量体重，空气栓塞处死，分离股骨颈，获得股骨颈样本，经切片等处理后，显微镜下作骨形态计量学检测。

Glioma is still one of refractory disease in the neurosurgical field; the development of new primary and adjuvant treatment is vital. Recently, the gene therapy of glioma is developed rapidly and there are many methods about the gene therapy that include: suicide gene therapy, immunologic gene therapy, drug resistangce gene therapy, angiostatin gene therapy and so on. The sucide gene therapy is the most potential approach of antitumer, these nonmammalian genes encode enzyme that convert nontoxic prodrugs into highly toxic metablites. Cells transfected with suicide genes are targeted for specific negative selection, witch can be induced by administrtion of the corresponding produg. Among the enzyme/produg combinations, two of the best characterized system are herpes simplex virus thymidine kinase /ganciclovir and Escherichia coli cytosine deaminase /5-flourocytosine (5-FC). The formor can convert the antiviral nucleoside analogs acyclovir , ganciclovir to their nucleoside monophosphate derivatives, the monophosphate forms are subsequently phosphorylated by endogenus cellular kinases to triphosphates, these molecules are potent inhibitors of DNA synthesis.

近年来脑胶质瘤的基因治疗发展迅速，应运而生的方法有自杀基因、免疫基因、多药耐药基因以及抗血管生成基因等，其中自杀基因被认为是最有前景的基因治疗方法，它又称病毒介导的酶／药物前体疗法，是利用转基因技术将哺乳动物细胞中所不含有的自杀基因转入到哺乳动物肿瘤细胞中，该基因表达的产物可将无毒的药物前体转化为毒性药物，从而选择性杀伤该肿瘤细胞，常用的自杀基因有单纯疱疹病毒-胸苷激酶基因和大肠杆菌胞嘧啶脱氨酶基因，前者催化无毒性抗病毒核苷类似物如丙氧鸟苷、无环鸟苷等成为单磷酸核苷衍生物，然后在内源性细胞激酶作用下转化为具有明显毒性的三磷酸核苷，作为DNA合成链的终止剂和DNA合成酶的抑制剂，干扰细胞DNA的合成；后者编码的胞嘧啶脱氨酶可催化5-氟胞嘧啶（5-FC）脱氨成为5-氟尿嘧啶（5-FU），然后代谢为有毒性的5-氟尿嘧啶-5′三磷酸（5-FUTP）和5-氟-2′脱氧尿嘧啶-5′磷酸（5-FdUTP），5-FUTP通过与UTP竞争性结合而抑制mRNA和tRNA的合成，5-FdUTP则作用于胸苷合成酶，导致TMP衰竭而阻止DNA的合成，最终诱导肿瘤细胞凋亡。

The tuberculosis patients with proteinic malnutrition emerge medicinal liver function injures easily in the treatment process, so that we should monitor the clinical treatment for their liver function changes and pay attention to the improvement in their nutritional conditions.

在肺结核并蛋白质营养不良的患者治疗过程中，较容易出现药物性肝损害。因此在临床治疗上，应注意监测其肝功能变化以及注意改善其营养状态，减少药物性肝损害发生。

To treatment 112 PAR patients by intergated using Antihistamine、rhinal spray 、microwave treatment and KANG LUO rhinitis tablet（composing antihistamine ingredient）.

联合使用抗组胺药、鼻腔局部喷雾剂、微波治疗、含抗组胺药的中成药治疗112例PAR患者。

METHODS: Bilateral common carotid arteries of rats in the ischemia and treatment groups were splinted for 30 minutes and reperfused for 1 hour to establish models of isehemic cerebral injury.

缺血组和治疗组大鼠夹闭双侧颈总动脉30min后再灌注1h，建立缺血性脑损伤模型；治疗组在缺血30min前腹腔注射参麦注射液2mL／kg（由红参、麦冬等中药组成）；缺血组不给药；对照组做假手术，不夹闭颈总动脉，也不给药。

Ca2+ blocker was given in control group. Their blood glucose level, blood pressure and Ualbumin excretions were determined both in the treatment and the control group before and after the treatment.

采用免疫比浊法测定2型糖尿病合并高血压患者的尿微量白蛋白，选择34例尿微量白蛋白正常的患者，随机分为2组，治疗组17人，在口服降糖药的基础上加咪达普利，对照组17人，在口服降糖药的基础上加钙离子拮抗剂，两组治疗前后均监测血压、血糖、糖化血红蛋白和UAE。

Methods A total of 34 diabetes patients with hypertension were studied. A dose of 5 mg imidapril was given daily in treatment group except oral medicine for decreasing glucose level. Ca2+ blocker was given in control group. Their blood glucose level, blood pressure and Ualbumin excretions were determined both in the treatment and the control group before and after the treatment.

采用免疫比浊法测定2型糖尿病合并高血压患者的尿微量白蛋白，选择34例尿微量白蛋白正常的患者，随机分为2组，治疗组17人，在口服降糖药的基础上加咪达普利，对照组17人，在口服降糖药的基础上加钙离子拮抗剂，两组治疗前后均监测血压、血糖、糖化血红蛋白和UAE。

A dose of 5 mg imidapril was given daily in treatment group except oral medicine for decreasing glucose level. Ca2+ blocker was given in control group. Their blood glucose level, blood pressure and Ualbumin excretions were determined both in the treatment and the control group before and after the treatment.

采用免疫比浊法测定2型糖尿病合并高血压患者的尿微量白蛋白，选择34例尿微量白蛋白正常的患者，随机分为2组，治疗组17人，在口服降糖药的基础上加咪达普利，对照组17人，在口服降糖药的基础上加钙离子拮抗剂，两组治疗前后均监测血压、血糖、糖化血红蛋白和UAE。

A dose of 5 mg imidapril was given daily in treatment group except oral medicine for decreasing glucose level. Ca2+ blocker was given in control group. Their blood glucose level, blood pressure and U??albumin excretions were determined both in the treatment and the control group before and after the treatment.

采用免疫比浊法测定2型糖尿病合并高血压患者的尿微量白蛋白，选择34例尿微量白蛋白正常的患者，随机分为2组，治疗组17人，在口服降糖药的基础上加咪达普利，对照组17人，在口服降糖药的基础上加钙离子拮抗剂，两组治疗前后均监测血压、血糖、糖化血红蛋白和UAE。

MethodsHepatocyte injury model was induced by CCl4 and the injured hepatocytes were incubated with rat serum obtained after oral administration of CWC. The hepatocyte proliferation rate and alanine aminotransferase concentration in cell culture medium were determined. 446 patients with chronic hepatitis were divided into experimental group and control group treated by Hu Gan Tablets, HGT） randomly. With physical sign, symptom and hepatic function as main indices, the therapeutic effect of CWC on patients with chronic hepatitis was evaluated.

方法以SD大鼠为供体制备复方五仁醇胶囊含药血清，CCl4诱导大鼠原代培养肝细胞损伤模型，采用血清药理学方法考察含药血清对损伤肝细胞增值和培养上清液中丙氨酸氨基转移酶的影响；将446例慢性乙型肝炎患者随机分成治疗组和对照组，以临床症状、体征、肝功能为主要指标，考察复方五仁醇胶囊的治疗效果。

But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊！不用提了。提到肉，真是糟透了。