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Results:(1) Progesterone-treated models showed intact nasal mucosa, regular ciliary lining and inactive glands;(2) Untreated or normal saline treated models showed disrupted mucosa, inverted cilia and massive mucosal infiltration of neutrophils;(3) Smearing of nasal discharge revealed limited vs abundant number of neutrophils in SD models treated with progesterone vs untreated or treated with normal saline.(4) Hoechst stain: significantly fewer apoptotic cells per field were found in progesterone-treated models (1.583 ± 0.28) compared with untreated or normal saline treated models (2.85 ± 0.285 and 4.8 ± 0.715, respectively).

结果:(1)用黄体酮滴鼻液治疗的SD大鼠鼻腔黏膜上皮完整,纤毛整齐,腺体开放不多;(2)用或不用生理盐水滴鼻液治疗的SD大鼠鼻腔黏膜上皮纤毛倒伏,上皮结构散乱,上皮层大量中性粒细胞浸润;(3)鼻腔分泌物涂片示黄体酮滴鼻液治疗的SD大鼠有少许中性粒细胞,而用或不用生理盐水滴鼻液治疗的SD大鼠鼻腔分泌物含有大量中性粒细胞;(4)Hoechst染色:用黄体酮滴鼻液治疗的SD大鼠鼻腔黏膜上皮凋亡细胞数[(1.583±0.28)/视野]明显少于用或不用生理盐水滴鼻液治疗的SD大鼠[分别是(2.85±0.285)/视野和(4.8±0.715)/视野]。

Methods: Treated 126 cases with cerebral hemorrhage with various medical treatments. Treated 31 cases of 77 hypertension patients with hypotensive drugs, 46 cases without hypotensive drugs; 87 cases by dehydration therapy with mannitol; 59 cases with brain protein hydrolysate, cattle encephalon glycoside and ignotin injection, including 9 cases with cattle encephalon glycoside and ignotin and 50 cases with brain protein hydrolysate; 18 cases with minimally invasive puncture, 108 cases without puncture. Compared efficacy of different therapy.

126例脑出血患者采用不同的内科治疗方法进行治疗,高血压患者77例中,降压药治疗31例,非降压治疗46例;甘露醇脱水治疗87例;脑苷肌肽与脑蛋白水解物治疗59例,其中脑苷肌肽治疗9例,脑蛋白水解物治疗50例;微创穿剌治疗18例,非微创穿剌治疗108例,对不同治疗方法的疗效进行比较。

2 Treatment method is less than a month treat a little patient to use method of massage drop medicine first, treat 1~2 week, 2~3min is massaged before daily drop medicine, be more than the little patient of a month, if drop medicine treats 1~2 week to did not see,improve to still have apparently weep the person that reach secretion, applied medicaments pressurization rinses lachrymal path, use pinhead of vein of skin of tube head of nylon of self-restrained and different type to grind blunt, make rinse a needle continuously, groovy operation, after syringe needle inserts lachrymal canaliculus, nylon the canal is secured with adhesive plaster at the head, undertake rinsing, 1 / D, with oxygen fluorine to lotion Sha Xing adds loose diluent of rice of ground a place of strategic importance, pressurization rinses 3~4 second, invalid still, undertake probing of groovy tear path is operated.

我科自2000年1月至2006年12月,共治疗新生儿泪囊炎178例、230眼,疗效满足,报告分析如下。1资料和方法1.1一般资料新生儿泪囊炎患儿168例、230眼,男102例,女66例,年龄:2d~3个月,均为本院眼科门诊确诊的新生儿泪囊炎患儿。1.2治疗方法小于1个月的首次就治患儿采用按摩滴药法,治疗1~2周,每日滴药前按摩2~3min,大于1个月的患儿,如滴药治疗1~2周未见明显好转仍有流泪及分泌物者,应用药物加压冲洗泪道,采用自制不同型号尼龙管头皮静脉针头磨钝,制成直的冲洗针,常规操作,针头插入泪小管后,将尼龙管用胶布固定于头部,进行冲洗,1次/d,冲洗液用氧氟沙星加地塞米松稀释液,加压冲洗3~4次,仍然无效的,进行常规泪道探通术操作。1.3治疗标准无流泪、无分泌物、泪道冲洗畅通,反之则无效,结果168例,230眼,治愈166例,228眼,其中按摩治疗49例,冲洗86眼,探通31眼。。。

Process can be called a disease for which melange is the specific treatment

作为特殊治疗物时,衰老过程可以被称为是疾病,虽然香料并不能长生不老。

Methods 181 patients with pelvic inflammatory disease were randomly divided into two groups,treatment group 93 patients in the basis of broad-spectrum antibiotic therapy was added Smilax capsule,the control group 88 patients with simply using broad-spectrum antibiotic therapy.

181例盆腔炎性疾病患者随机分为两组,治疗组93例在广谱抗菌药物治疗基础上加用金刚藤胶囊,对照组88例单纯用广谱抗菌药物治疗。

Methods:140 of acute suppurate tonsillitis according with diagnosis standard were randomly divided into treating group and control group.70 of treating proup is used penicillin and 0.05%iodophor for external use.70 of control group is used penicillin.

方法将符合诊断标准的140例急性化脓性扁桃体炎随机分为治疗组和对照组,治疗组70例采用抗菌药物青霉素联合局部应用0.5%碘伏外擦治疗;并与同期对照组70例采用抗菌药物青霉素治疗的患儿进行比较。

Methods:140 of acute suppurate tonsillitis according with diagnosis standard were randomly divided into treating group and control group.70 of treating proup is used penicillin and 0.05%iodophor for external use.70 of control group is used penicillin.Results:Two groups have temperature 、suppurate secretion、 congestion in part 、 pharynx pain descending.

方法将符合诊断标准的140例急性化脓性扁桃体炎随机分为治疗组和对照组,治疗组70例采用抗菌药物青霉素联合局部应用0.5%碘伏外擦治疗;并与同期对照组70例采用抗菌药物青霉素治疗的患儿进行比较。

The compounds of the invention are also useful in the prevention and treatment of TRX-mediated diseases, such as autoimmune, allergic and inflammatory diseases, and in the prevention and/or treatment of diseases of the central nervous system, such as neurodegenerative diseases, The present invention further provides pharmaceutical compositions comprising the hydroxamic acid derivatives and safe dosing regimens of these pharmaceutical compositions, which are easy to follow, and which result in a therapeutically effective amount of the hydroxamic acid derivatives in vivo.

本发明的化合物还可用于预防和治疗TRX-介导的疾病,例如自身免疫性、变应性和炎性疾病,并且用于预防和/或治疗中枢神经系统疾病,例如神经变性性疾病。本发明还提供了包含所述异羟肟酸衍生物的药物组合物以及这些药物组合物的易于依从并且在体内产生治疗有效量的所述异羟肟酸衍生物的安全剂量方案。

objective we start with clinical research to explore the ability and mechanism of ion conduction with chinese herbs to curing ovulatory obstacle.methods adopting the methods of clinical observation random contrast.select the cases of ovulatory obstacle dividing randomly into two groups:therapeutic group and control group,the patients of therapeutic group using ion conduction with chinese herbs with act'on nourishing blood and promoting blood circulation to dissipate blood stasis when follicle grow up to 1.4cm.we take the decoction of jia jian tao hong si wu tang conducting the unilateral lower abdomen which has the dominant follicle,treating continuously for 4~8 days and observing ovulation.the patients of control group inject hcg 10000unit when follicle grow up to 1.8cm and observing ovulation.appraising two groups ovulated rate and pregnancy rate,and detect fsh、lh、e2、p at sixteen to eighteen days of menstrual cycle.results ion conduction with chinese herbs can significantly inspires ovulation and its effection is evidently higher than control group and has a higher pregnancy rate,no side effect of ovarian hyperstimulation syndrome.conclusion ion conduction with chinese herbs has significant function on inspiring ovulation.the target effection of treating ovulatory obstacle is exact.this method has a ovulated rate and higher pregnancy rate.

采用临床观察、随机对照的方法,选择排卵障碍的患者,随机分为治疗组和对照组,治疗组在b超监测卵泡生长达到1.6cm时,给予具有养血、活血化瘀作用的加减桃红四物汤水煎剂,用离子导入仪将中药水煎剂导入有优势卵泡的一侧少腹部,连续治疗4~8时天,同时连续监测卵泡排出情况。对照组在b超监测卵泡达到1.8cm时,开始采用hcg10000u肌注,连续b超监测卵泡排出情况。评价两组排卵率及受孕率,同时在月经周期的第16~22天抽血查fsh、lh、e2、p。结果运用离子导入的方法将具有促排卵作用的加减桃红四物汤水煎剂导入有优势卵泡的一侧附件,其促排卵的作用优于用hcg肌注促排卵,而且受孕率高,无卵巢过激综合征之虞。结论中药离子导入具有显著的促排卵作用,其治疗排卵障碍的靶向作用确切,排卵率及受孕率高。

If they choose to Thiazide diuretics or β-blockers as initial treatment of patients with complex, will be significant cost savings, resulting in better price efficiency.

若选择噻嗪类利尿剂或β—受体阻滞剂作为病人的初始治疗物,将节约大量成本,产生较好的效价比。

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