治疗地

Objective: To confirm the hypolipidemic therapy effect of XIEZHIPING whichcomposed of Alisma Rhizoma the principal drug and probe the mechanismof hypolipidemic action from the view of animal model experiment in vivoto cell culture in vitro, and finally establish the base of new naturalhypolipidemic product by the way of experiment on the golden hamsterhyperlipoidemia animal model and HepG2 cell line culture.

目的： 通过对金黄地鼠高脂血症动物模型及HepG2离体细胞培养的实验研究，证实以建泽泻为君药的纯中药组方—&泻脂平&的可靠降脂作用，并进一步从细胞分子水平初步探讨其降脂作用机理，为研发治疗高脂血症的有效天然药物奠定基础。

To confirm the hypolipidemic therapy effect of XIEZHIPING which composed of Alisma Rhizoma the principal drug and probe the mechanism of hypolipidemic action from the view of animal model experiment in vivo to cell culture in vitro,and finally establish the base of new natural hypolipidemic product by the way of experiment on the golden hamster hyperlipoidemia animal model and HepG2 cell line culture.

通过对金黄地鼠高脂血症动物模型及HepG2离体细胞培养的实验研究，证实以建泽泻为君药的纯中药组方—&泻脂平&的可靠降脂作用，并进一步从细胞分子水平初步探讨其降脂作用机理，为研发治疗高脂血症的有效天然药物奠定基础。

Treatment of food allergy using very small but increasing daily doses of actual foods has been reported, 162 and in one controlled trial 163 12 of 14 patients successfully completed the program and could tolerate previously allergenic foods.

食物过敏的治疗用实际食品很小，但每天都在增加剂量据报道，162和对照试验的14例163 12 1成功地完成了程序，能够经受先前引起过敏的食物。

Conclusion］Good results can be obtained in hips with acetabular protrusion after reconstructed with autogeneous or allogeneous bone grafting and total hip arthroplasty.

结论］应用自体股骨头骨或异体颗粒骨移植填充髋臼连系多孔生物型髋臼假体，治疗Otto's病，可获得较好的疗效，移植骨可与宿主骨很好地连系在一路。

The mineral kingdoms suggest this type of treatment over allopathic medicine as it is far more supportive of ascension.

矿石王国建议这种治疗而不是对抗疗法的药物，因为这远远更好地支持提升。

Although the most effective method of treating the problem at the time, it was only partially ameliorative in cases where damage to the neonate had already been done.

尽管这是那时最有效的治疗方法，它只是在部分地改良对新生儿造成的伤害。

DCs acquired by our reformed methods express both CD83 and CD 14 molecules highly, and have a higher density than other domestic reports. The higher TNF in DCs culture medium of HC patient suggests DCs in patient still have antigen presenting ability and by optimization the culture medium would improve its presenting ability and have a potential value in design and application individual vaccine. Although antigens pulsed DCs have a decrescent antigen presenting ability but BCG HSP70 could induce its mature and improve its presenting ability. Suggests BCG HSP70 would be a useful mature inducer. Lymphocytes primed by DCs based HC vaccine have the specific cytotoxicity against HCC lines. The CTL after freezing and anabiotic could prophylaxis and therapy HC xenograft on nude mouse. The results also suggests that CD4〓 lymphocytes play a important role in HC with a good differentiation and would be useful in treatment this kind of HC. After being activated by Peptide LLNQHACAV of hAFP and apoptotic HCCs pulsed DCs respectively, the culture medium of activated lymphocytes both contains a high level Th1 cytokines IL-12 and TNF. Primed lymphocytes appeared a characteristic of NK cells. DCs not only inhibited the growth of human HCC and other cancer cells in vitro but also prevented the growth of HC xenograft on nude mouse in vivo. There are at least three kinds of mechanism playing important role in DC based vaccine ,there are inhibition of DCs, HC specific CTL and cytokines pathway.

诱导出的DC共同表达CD83和CD14分子，CD83分子表达明显高于国内报道；肝癌患者DC培养上清中TNF水平高于健康人，提示肝癌患者DC仍具一定的抗原呈递能力，适当调控可使其行使APC功能，以期在肝癌个体化疫苗中发挥作用；DC负载肝癌可溶性抗原后，抗原呈递能力降低，BCG HSP70可促进DC成熟，增加其抗原呈递能力，预示BCG HSP70有可能成为促进DC活化和成熟的另一重要分子；肝癌DC疫苗在体外诱导肝癌特异性淋巴细胞，活化的淋巴细胞在体外对肝癌细胞的杀伤以特异性CTL为主，同时分泌较高水平Th1型细胞因子IL-12和TNF，并抑制4种肝癌细胞生长；冷冻复苏后的肝癌特异性淋巴细胞可以预防和抑制人肝癌裸鼠皮下移植瘤，提示DC负载肝癌可溶性抗原后诱发的MHC-Ⅱ类限制性CD4〓T细胞有可能在分化程度高的肝癌治疗中发挥作用；用DC和HLA-A2〓DC分别负载凋亡肝癌细胞和hAFP218-226位LLNQHACAV HLA-A2限制性九肽，在体外诱导肝癌特异性淋巴细胞，活化后的CTL细胞分泌较高水平的Th1型细胞因子IL-12和TNF，并具较强杀伤活性，此CTL同时具备NK细胞特征；DC对肿瘤细胞的抑制作用可能是通过吞噬实现的，Fas-L在DC抑制中也起一定作用；DC对人肝癌裸鼠皮下移植瘤的抑制率为97％；在肝癌DC疫苗的作用中，至少联合3种以上机制，即通过DC的直接作用、肝癌特异性CTL和细胞因子途径直接或间接地杀伤和抑制肝癌细胞。

Later, it was recommended that a warning be placed on bottles of dextran that if an anaphylactoid reaction developed, the infusion must be stopped at once and active treatment instituted.

以后，一个对瓶装的葡聚糖的警告被提出，即如果过敏反应一旦发生，注射应立即停止，并实施有效地治疗。

At present, treatment options for androgenetic alopecia include topical minoxidil tincture, oral finasteride, and autologous hair transplantation.

目前用于治疗雄激素源性脱发的方法有：米诺地尔局部外用，口服非那雄胺和自体头发移植。

Objective: To investigate the effects of a new agent fasudil on delayed cerebral vasospasm after aneurysmal subarachnoid hemorrhage.

目的：临床研究盐酸法舒地尔对动脉瘤性蛛网膜下腔出血后发生脑血管痉挛的治疗意义。

She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了，但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场，你等着挨绳子吧！