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Objective :To evaluate the efficacy and safety of diflunisal in treatment of rheumatoid arthritis and degenerative osteoarthritis.

目的:评价二氟尼柳治疗类风湿性关节炎和退行性骨关节炎的临床疗效和安全性。

In order to study the therapeutic effect of Sodium Hyaluronate injection of articular cavity and taking orally "JIN GU TONG XIAO WAN"(JGTXW, a TCM preparation for osteopathy disease) in the treatment of osteoarthritis of knee, 130 cases of OA were randomly divided into the treated group (66 cases, treated by SH and JGTXW) and control groups(64 cases, treated only by SH); The effect such as local pain, tumidness, joint movement and so on of the two groups in one year were observed and evaluated according to Lysholm criterion.

骨性关节炎是一种常见的老年退行性关节软骨病,随着我国人口的老年化增高,发病亦越来越多,严重影响老年人的生活质量,对膝关节骨性关节炎的治疗方法多,但疗效都均不太理想,不能阻止或延缓疾病的进展,近年来,以透明质酸制剂为代表的氨基糖类黏弹性物质补充疗法,在防治OA的基础研究和临床应用上取得了良好效果,为OA治疗寻找到了新的途径〔1〕。

Methods Twenty-one cases of knee pyoarthrosis were treated by debridement and subtotal synovectomy under arthroscope and combined with intravenous antibiotics and systematic postoperative rehabiliation.

目的 介绍关节镜下清理术在早期膝关节化脓性关节炎治疗中的应用方法 21例化脓性膝关节炎在关节镜下行关节清理术,同时行置管冲洗术。

To explore effects of nicotin cholinergic pathway on collagen induced arthritis in rats.

目的 探讨烟碱样胆碱能通路对胶原性关节炎的作用,为关节炎等自身免疫性疾病寻找新的治疗途径。

An integrated therapy deals with the extra- and intraarticular progressive pathologic changes, and kinesiologic management of OA is suggested for the management of knee OA.

膝骨关节炎的处理建议采用综合治疗,以改善膝骨关节炎患者关节内外进展性的病理变化和运动障碍。

Hyperuricemia and acute gouty arthritis model was made with Oxonic Acid potassium and Sodium Urate injected into abdominal cavity and right ankle joint cavity respectively.

目的研究痛风速效灵对急性痛风性关节炎模型大鼠不同时相步态和关节组织形态学的影响,探讨其治疗急性痛风性关节炎的作用机制。

Objective: To analyze the clinical characteristics of diagnosis and therapy of pyogenic sacroiliitis. Methods: 4 cases were analyzed retrospectively and reported; and related literatures were reviewed.

目的:回顾分析4例误诊为强直性脊柱炎的化脓性骶髂关节炎的病例,探讨化脓性骶髂关节炎的临床表现、诊断、治疗方法。

Objectives:Through the detection of the expression level of interleukins-1β(IL-1β), matrix metalloproteinase 9(MMP-9) and nuclear factor kappa B in Synovium and the detection of the concentration of IL-6 and TNF-αin serum of collagen induced arthritis Wister rat, to investigate the relationship between IL-1β、MMP-9、NF-κB and arthritis index in the development of arthritis,and to understand the pathology of synoviocyte.This may provide an experimented proof for the diagnosis of clinical rheumatical arthritis. Methods: Thirty male Wistar rats were randomly divided into two groups,namely the model controlled group and the normal controlled group,three subgroups were randomly divided in model group and controlled group separately.

目的:通过对白细胞介素1β,基质金属蛋白酶-9,转录因子核因子κB在胶原性关节炎大鼠滑膜细胞表达水平的观察,同时监测同期血清细胞因子IL-6和TNF-α的浓度,旨在探讨白细胞介素1β,基质金属蛋白酶-9,转录因子核因子κB与RA发生发展及其与关节指数之间的相关性,了解炎性病变关节滑膜细胞的病理生理状态,进一步为类风湿关节炎的临床治疗提供实验依据。

HUANG Jian,ZHUO Lianshi,WANG Yongyu(College of Traditional Chinese Medicine of Chongqing Medical University,401331,China)Abstract:ObjectiveTo observe the effects of massage on synovia SOD,MDA and NO contents in rabbits with Knee Osteoarthritis.

目的观察推拿加功能训练对膝骨关节炎家兔模型关节液中超氧化物歧化酶、丙二醛和一氧化氮的影响,探讨推拿加功能训练治疗膝骨关节炎的机制。

As many studies have proved ,total glucosides of paeony and methotrexate can potentially prevent or limit the progression of rheumatoid arthritis.

在体外实验中,甲氨蝶呤和白芍总苷单独或联合作用均可显著抑制兔佐剂性关节炎滑膜细胞的增殖,这可能是甲氨蝶呤和白芍总苷发挥对类风湿关节炎治疗作用的重要机制之一。

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