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Unconjugated antibodies show significant efficacy in the treatment of solid tumors by monotherapy and combining with chemotherapy or radiotherapy.

单克隆抗体单治疗和联合化疗、放疗在实体瘤治疗中显示出了很好的疗效,抗体与放射性核素结合的放射免疫性治疗也有明显的疗效。

Unconjugated antibodies show significant efficacy in the treatment of solid tumors by monotherapy and combining with chemotherapy or radiotherapy. Radioimmunotherapy is that antibodies conjugate to radionuclides shows significant efficacy, too.

单克隆抗体单一治疗和联合化疗、放疗在实体瘤治疗中显示出了很好的疗效,抗体与放射性核素结合的放射免疫性治疗也有明显的疗效。

From January 2007 to December 2007, the samples of this study were the patients who were under 15 years old in alleviated period by purposive sampling. They were divided into two groups:(1) 96 patients participated in the Chinese and western medicine care group;(2) 64 patients participated in the western medicine care group. The SF-36 health questionnaire for pre- and post-tests were administered to all participants. The cost took account of national health insurance apply claims and ratio of hospital's cost and fee.

收案期间为2007年1月1日至12月31日,样本来源分别为中医优质门诊照护计划合作之医疗院所及西医小儿过敏科门诊,采立意取样的方式,年龄为15岁以下由医师确诊为小儿气喘患童,比较其不同治疗模式:接受中西医联合照护组与只接受西医治疗组,在治疗前后测量其生活品质的改变情形,并收集各组健保申报费用及医院成本费用比率资料,最后进行两组成本效果分析比较。

The cost and human resources demand of the latter are higher and it takes time to reach the effects. It is difficult to manage without the legal compulsion. These preceding two patterns are able to provide all drug addicts therapy, comparing with the displacing therapy which can only serve the heroin-addicts. It is unexpendable to develop these two systematic and completed local professional abstained patterns due to the above.

但相较於替代疗法只能针对海洛因注射的个案提洪治疗服务,社区追踪治疗模式与社区药瘾复健模式则可以提洪治疗服务给所有的药瘾病患,故发展这两种有系统地、完整的本土化戒治医疗专业处遇模式,是不可缺少的重要一环。

Most patients receiving long-term acid suppression therapy for physician-diagnosed PUD in community practice settings are likely to have HP-negative, uninvestigated dyspepsia.

Allison医师及其同事表示,在检验及治疗曾罹患PUD病患的建议指导方针中,假设PUD可以被处理,并且成功的消灭HP可以排除未来治疗及用药的需求,大多数在社区医院经医师诊断为PUD,且接受长期酸抑制治疗的病患,常呈现HP阴性反应,且有未诊断出的消化不良症。

Fifty 6-month-old unmated female SD rats were randomly divided into 5 groups: sham operated group, ovariectomized and treated with estrogen group, ovariectomized and treated with propranolol group, ovariectomized and treated with both estrogen and propranolol group, ovariectomized and treated with placebo group .

将50只健康雌性未交配6个月龄SD大鼠随机分为5组:①假手术组。②去卵巢后雌激素治疗组。③OVX后普萘洛尔治疗组。④OVX后雌激素+普萘洛尔治疗组。⑤OVX后安慰剂组。

Medical treatment and consequences of experimental and unproven medical treatment or drug therapy.

试验性医疗治疗及其产生的后果,或未经证实的医疗治疗或药物治疗

Objective To investigate the curative effect of left ventricular hypertrophy with uretic indapamide, Methods 96 patients wiht LVH were divided into two groups, 50 patients in A group were treated with indapamide 2,5~5mg/d, and 46 patients in B group with nifedipine 20~60mg/d for 12 months, Results Blood pressure、interventricular septum thickness、left ventricular posterior wall thickness、left ventricular mass index and left ventricular ejection fraction in all cases were improved after treatment, A group was better than B in LVEF, Conclusion Both indapamide and nifedipine can regress LVH, and improve left heart function

目的 观察新型噻嗪类利尿剂吲达帕胺逆转左心室肥厚的效果。方法 96例高血压LVH患者,分别给予吲达帕胺(A组,50例)2,5~5mg/d和硝苯地平控释片(B 组,46例)20~60mg/d持续12个月治疗,观察治疗前后血压及左室结构变化。结果两组治疗前后血压、室间隔厚度、左心室后壁厚度、心室重量指数和左心室射血分数均有改善(P<0,05~0,01),A组在改善LVEF方面优于B组(P<0,05)。结论吲达帕胺具有与硝苯地平类似的逆转LVH作用,有明显改善左心功能作用。

12H treatment group compared with 12h model group: the level of SOD, MDA of the Gardenoside group is no different with the model group; the level of the SOD of the Baical in group increase and the level of MDA is no different; the level of SOD of the Concha Margatitifera Usta is no different and the MDA of it decreased than the model; the level of SOD of the Cholic Acid group increased and the level of MDA decreased; the level of SOD of the Hefang Group increased and the level of MDA of it decreased than the model group.

考虑nNos可能只是参与缺血早期的神经毒性作用。到缺血24小时这一时程已经减低或耗竭。大鼠局灶性脑缺血12小时模型组缺血脑组织P53光密度值含量较正常组明显增高(p<0.01)。珍珠母治疗脑缺血12小时组缺血脑组织P53光密度值较缺血12小时模型组明显降低。胆酸治疗脑缺血12小时组缺血脑组织P53光密度值较缺血12小时模型组明显降低(p<0.05)。栀子苷治疗脑缺血12小时组缺血脑组织P53光密度值较缺血12小时模型组明显降低(p<0.05)。

24H treatment group compared with 24h model group: the level of MCP-1 of the Gardenoside group decreased, but the level of MIP-1 of it is no different with the model group; the level of the MCP-1 of the Baicalin group increase and the level of MIP-1 of it all decreased; the level of MCP-1 and MIP-1 of the Concha Margatitifera Usta all decreased; the level of MCP-1 of the Cholic Acid group decreased and the level of MIP-1 is no different with the model group; the level of MCP-1 and MIP-lof the Hefang Group decreased than the model group.

在本实验中,脑缺血能够诱导P53蛋白表达,P53蛋白可能参与调控缺血后神经细胞延迟性死亡的病理生理过程,药物通过抑制细胞凋亡,从而发挥治疗作用。五、大鼠局灶性脑缺血12小时模型组缺血脑组织HSP70光密度值含量较正常组明显增高(p<0.05)。珍珠母治疗脑缺血12小时组缺血脑组织HSP70光密度值较缺血12小时模型组无显著性差异(p>0.05)。胆酸治疗脑缺血12小时组缺血脑组织HSP70光密度值较缺血12小时模型组无显著性差异(p>0.05)。

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