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Results:(1) Progesterone-treated models showed intact nasal mucosa, regular ciliary lining and inactive glands;(2) Untreated or normal saline treated models showed disrupted mucosa, inverted cilia and massive mucosal infiltration of neutrophils;(3) Smearing of nasal discharge revealed limited vs abundant number of neutrophils in SD models treated with progesterone vs untreated or treated with normal saline.(4) Hoechst stain: significantly fewer apoptotic cells per field were found in progesterone-treated models (1.583 ± 0.28) compared with untreated or normal saline treated models (2.85 ± 0.285 and 4.8 ± 0.715, respectively).

结果:(1)用黄体酮滴鼻液治疗的SD大鼠鼻腔黏膜上皮完整,纤毛整齐,腺体开放不多;(2)用或不用生理盐水滴鼻液治疗的SD大鼠鼻腔黏膜上皮纤毛倒伏,上皮结构散乱,上皮层大量中性粒细胞浸润;(3)鼻腔分泌物涂片示黄体酮滴鼻液治疗的SD大鼠有少许中性粒细胞,而用或不用生理盐水滴鼻液治疗的SD大鼠鼻腔分泌物含有大量中性粒细胞;(4)Hoechst染色:用黄体酮滴鼻液治疗的SD大鼠鼻腔黏膜上皮凋亡细胞数[(1.583±0.28)/视野]明显少于用或不用生理盐水滴鼻液治疗的SD大鼠[分别是(2.85±0.285)/视野和(4.8±0.715)/视野]。

objective to raise the level of regarding congnition,prevention,diagnosis and therapy on multiple organ dysfunction syndrome.methods report the process and correlative therapy on one case who occured with mods involving 6 organs after hemorrhagic shock lead to heartbeat and respiration stopping suddenly and resuscitated resulting in left nephrostome titanium nip falled off accidentally from left kidney lymphatic fastening.at the same time,the author reviewed correlative literature and introduce the investigative progress about mods.results one case who happened with mods following hemorrhagic shock,heartbeat and respiration stopped suddenly was diagnozed and resuscitaed.6 organ dysfuncted including brain,heart,lung,liver,kidney and the digestive system.after being given therapy integrated chinese and western medicines,allopathy and nutritional treatment,all circadian parameters of the case came back in gear and discharged at last.conclusion the mechanism about mods is very complicated.because of serious infection,hurt and oxygen-lack,excessive inflammatery reaction activates multifarious cell factors and inflammatery mediums,which improve the happen-rate of mods.wiping off pathogeny,providing life-sustain treatment and recognising sirs and mods in time and adopting corresponding therapy,such as treatment integrated chinese and western medicines,can improve the hit-rate of cure on mods.

作者:王静恩,蔡金芳,王志华,谢晓洪多器官功能障碍综合征;中西医结合;治疗;休克,出血性目的提高对多器官功能障碍综合征(multiple organ dysfunction syndrome,mods)的认识、预防、诊断、治疗水平。方法报告成功抢救1例经腹腔镜左肾淋巴管结扎手术后左肾静脉钛夹意外脱落失血性休克,导致心跳呼吸骤停复苏后再手术并发mods累及6个脏器功能衰竭过程及有关治疗,并复习相关文献,介绍目前关于mods的研究进展。结果确诊1例因失血性休克心跳呼吸骤停复苏后并发mods,累及脑、心、肺、肝、肾、血液、胃肠等6个脏器。经积极采取中西医结合对症、支持救治,各生理指标全部恢复正常,康复出院。结论 mods的发生机制非常复杂,在严重感染、创伤、缺氧等打击下,失控的过度炎症反应激活多种细胞因子和炎症介质的释放,使mods发生率升高。尽早去除病因,尽早给予各种生命支持治疗,尽早对可能发生全身炎症反应综合征、mods识别并给予干预治疗,包括中西医结合治疗能改善mods的救治成功率。

All the patients were followed up for months and measured respectively the changes of heart rate, blood puessure and cardiac function by the colur dopper ece.results48 patients completed the treatment.the lvedd, lvesd, heart function and symptoms were improved in both groups while the treatment group was more obvious than the control group(p<0.05).the result of hr and bp decreased significantly after treatemt comparatively(p<0.05), while the hr in the treatment decreased more obvious than the control group (p<0.01),but there was no significant difference in hr(p>0.05).conclusionon the basis of routine therapy metoyrolol and shengmaimai capsule can improve the symptoms and heart function significantly in patients with crf and chf.

随访6个月,分别测量治疗前后心率、血压,采用彩色超声心动图测量心功能进行疗效观察。结果48例患者完成研究,两组治疗后左心室舒张末径,左心室收缩末径、,心功能,症状均有改善,但治疗组比对照组明显,两组比较有显著性差异(p<0.05),两组治疗后血压心率较治疗组明显下降(p<0.01),两组患者治疗后血压无显著性差异(p>0.05)而心率有非常显著性差异(p<0.01)。

All patients were accepted decopper treatment and common nursing care,and patients in therapy group were accepted hot fomentation and cheirapsia treatment guided by nurses.Their effects were observed after the end of courses of treatment in hospital.Results When the courses of treatment in hospital ended,3 patients(7.69%)in therapy group were clinically cured,16 cases(41.03%)acquired significant effect,and 17(41.03%)patients'conditions were improved.

71例WD扭转痉挛型患者随机分为对照组和治疗组两组,对照组32例,治疗组39例,对照组行常规驱铜治疗和护理,治疗组则在常规驱铜治疗和护理基础上,在护理人员指导下予热敷、按摩治疗,2个月疗程结束后观察疗效。

Under the circumstances that on the one hand,the high metabolic rate needs to be supported,on the other hand,the organ can't effectively use the nutrients and get rid of the metabolites; we provide nutritional support at different stages to minimize serious complications.

①短程大剂量山莨菪碱和地塞米松联用的综合治疗方法;②"分阶段代谢营养支持"治疗;③采用自制的"解毒固本冲剂"配合治疗;④针对"炎性介质、细菌、内外毒素"等8个方面,提出了多环节兼顾和并治的12条综合治疗具体措施;⑤生长激素和生长抑素治疗等;⑥手术治疗等。

Pathological observations showed that the bone marrow and spleen of non-treated IMAA mice demonstrated typical aplastic anemia pattern, including bone marrow failure, marked splenatrophy, but the bone marrow and lymphoid tissues in the IMAA mice of irradiation-treated group were recovered to normal at day 28 after treatment.

结果表明:①IMAA组小鼠活存率为12.5%,平均存活时间为27.4 13.4天,照射治疗组活存率为100%,平均存活时间60天以上,单纯照射组无死亡;②外周血白细胞数:IMAA组呈进行性下降,直至死亡,照射治疗组第10天与免疫再障组相似,以后开始缓慢回升,基本上达到治疗前水平;③红细胞比容:未治疗IMAA组于14天后呈进行性降低,至第35天比实验前减低2/3,照射治疗组与单纯照射组一样,第14天有轻度减低随后升高,至35天接近正常;④骨髓有核细胞数:IMAA组呈进行性减低,无恢复趋势,照射治疗组于一过性减低后迅速增加,第28天达到正常水平;⑤骨髓和淋巴组织病理形态观察:IMAA组小鼠呈典型再生障碍性贫血病理改变,骨髓造血衰竭,脾脏明显萎缩,而照射治疗组于第28天骨髓和脾淋巴脏组织基本上恢复正常。

Methods17 cases with striae graviderum in abdomen were treated by radiofrequency at 200~600j, five times for a course of treatment, meanwhile, taking photographs and observing the reaction before and after treatment.results17 patients had treated for a course of treatment, the total effective rate was 94%.there were not any complication.conclusionradiofrequency is a non-invasive and effective treatment for striae gravidarum.

应用射频治疗仪对17例妊娠纹患者进行治疗治疗能量200~600j,5次为一疗程,治疗前后给患者拍照,并观察疗效。结果:共治疗17例患者,16例治疗1个疗程,总有效率为94%,未出现任何皮肤灼伤等并发症。结论:射频治疗技术无创、安全,是治疗腹部妊娠纹的一种较好方法。

The nearly half of psychotherapies applied (46.72%) were consistent with some theories of modern psychotherapy, such as Supportive Therapy, Behavioral Therapy, Cognitive Therapy, etc., and some therapies such as Emotion Inter-resistance Therapy belonged to unique treatments of TCM.

有近一半( 46.72%)的案例所使用的心理治疗方法,与现代心理治疗的某些理论一致,如支持治疗、行为治疗、认知治疗等,另有一些属于中医独特的治疗方法,如情志相胜治疗

Nearly half of psychotherapies applied (46.72%) were consistent with some theories of modern psychotherapy, such as Supportive Therapy, Behavioral Therapy, Cognitive Therapy, etc., and some therapies such as Emotion Inter-resistance Therapy belonged to unique treatments of TCM.

有近一半(46.72%)的案例所使用的心理治疗方法,与现代心理治疗的某些理论一致,如支持治疗、行为治疗、认知治疗等,另有一些属于中医独特的治疗方法,如情志相胜治疗

The current diagnosis included neurosis (16.39%), stress-related disorder (10.66%) and hysteria (8.20%).nearly half of psychotherapies applied (46.72%) were consistent with some theories of modern psychotherapy, such as supportive therapy, behavioral therapy, cognitive therapy, etc., and some therapies such as emotion inter-resistance therapy belonged to unique treatments of tcm.

按现代诊断分别为神经症(16.39%)、应激相关障碍(10.66%)和癔症(8.20%)。有近一半(46.72%)的案例所使用的心理治疗方法,与现代心理治疗的某些理论一致,如支持治疗、行为治疗、认知治疗等,另有一些属于中医独特的治疗方法,如情志相胜治疗

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