没食子酸

In this paper reported a new technology of preparing butyl gallate from sodium gallate and n-chlorobu-tane.

报道了由没食子酸钠和氯代正丁烷合成没食子酸丁酯的新工艺。

The article in recent years the research progress of disease of oral cavity of TP prevention and cure makes one overview. The compositive TP of the basic research 1.1 TP of 1 TP is the floorboard that phenolic apperception of a kind of many hydroxyl closes matter, 25% what hold tea dry weight about, its are main component includes to express gallnut of gallnut catechu element gallnut of element of catechu of gallnut of acerbity ester, watch, watch catechu element is acerbity element of catechu of ester, watch, express gallnut of gallnut catechu element among them acerbity ester content is highest, occupy the 80%[1] of catechu element about, fighting oxidation with its unique element structure, fight the position with fight the respect such as tumor to have choppy, significant. The 1.2 TP absorption in oral cavity and metabolization Lee [2] is measured normally inside a hour after healthy person is chewing green tea Xie Huo contains juice of gargle green tea, content of the TP in saliva is very high, after observing green tea passes salivary enzymatic hydrolyze, TP is slow release and in oral cavity;Yang of local play action [the salivary level after 3] checked 6 volunteers to drink tea, chroma of the TP in making clear the saliva after drinking tea as a result is serous TP pH indicator 2 times, and the salivary TP concentration that contains gargle tea solution a few minutes to be able to produce higher level, and TP can be absorbed through oral cavity mucous membrane.

本文就近年来TP防治口腔疾病的探究进展作一综述。1 TP的基础探究1.1 TP的组成TP是一类多羟基酚类化合物的总称，约占茶叶干重的25%，其主要成份包括表没食子儿茶素没食子酸酯、表没食子儿茶素、表儿茶素没食子酸酯、表儿茶素等，其中表没食子儿茶素没食子酸酯含量最高，约占儿茶素的80%[1]，并以其独特的分子结构在抗氧化、抗突变、抗肿瘤等方面占有重要的地位。1.2 TP在口腔中的吸收和代谢Lee等[2]测得正常健康人在咀嚼绿茶叶或含漱绿茶液后的一个小时内，唾液中TP含量很高，并观察到绿茶通过唾液酶水解后，TP缓慢释放并在口腔局部发挥功能；Yang等[3]检查了6位志愿者饮茶后的唾液水平，结果表明饮茶后唾液中TP浓度是血浆TP浓度的2倍，而含漱茶溶液几分钟即可产生更高水平的唾液TP浓度，且TP可通过口腔黏膜吸收。

Effects of Tea Catechins, Epigallocatechin, Gallocatechin, and Gallocatechin Gallate, on Bone Metabolism

茶中的儿茶酚：表没食子儿茶素，没食子儿茶酸和没食子儿茶酸没食子酸盐对骨代谢的作用。

Results Eleven compounds were isolated and identified as:quercetin(1),kaempferol(2),quercitrin(3),protocatechuic acid(4),gallic acid(5),protocatechuic acid ethyl ester(6),ethyl gallate(7),vanillic acid(8),1,5,7-trihydroxyl-3methylan...

结果得到11个化合物，分别鉴定为：槲皮素(1)、山柰酚(2)、槲皮苷(3)、原儿茶酸(4)、没食子酸(5)、原儿茶酸乙酯(6)、没食子酸乙酯(7)、香草酸(8)、1，5，7-三羟基-3-甲基蒽醌(9)、琥珀酸(10)、5-羟甲基糠醛(11)。结论化合物6、7、9、11为首次从该属植物中分离得到。

Result: Seven phenolic compounds were identified as rosmarinic acid(1),gallic acid(2),gentisic acid 5-O-(6′-O-galloyl)-β-D-glucopyranoside(3),caffeic acid(4),p-coumaric acid(5),ethyl caffeate(6) and acteoside(7),respectively.

结果：分离得到7种酚类化合物，经结构鉴定为：迷迭香酸(1)，没食子酸(2)，龙胆酸5-O-(6′-O-没食子酰基)-β-D-吡喃葡萄糖苷(3)，咖啡酸(4)，对香豆酸(5)，咖啡酸乙酯(6)和acteoside(7)。

On the basis of spectral analysis, these compounds were identified as Kaempferol , Kaempferol-3-O-β-D-glucopyranoside , Kaempferol-3-O-β-D-galactopyranoside, Quercetin , Quercetin-3-O-β-D-arabinopyranoside, Quercetin-3-O-β-D-galactopyranoside, gallic acid, methyl gallate-4-O-β-D- galactopyranoside, caffeicacid, methyl caffeate, 4-cafeoyl-(3"a, 4"a, 5"β)- trihydroxyquinic acid, 3"-cafeoyl-(3"a, 4"P, 5"P )-trihydroxyquinic acid methyl ester, 5"-cafeoyl-galactonic acid , pumiloside, loganic acid , 5R,6S,7E-megastima-3-on-7-en-9-ol 9-O-β-D-glucopyranoside. 2a, 3β-dihydroxy-oleanoic acid , 2a, 3β, 23-trihydroxy-oleanoic acid, 3a, 6a-dihydroxy-oleanoic acid, 3β-hydroxy-ursoic acid, 2a, 3a, 23-trihydroxy-ursoic acid , 2a, 3β, 23-trihydroxy-ursoic acid, 2β, 3β, 19a -trihydroxy-ursoic acid, 2a , 3β, 19a -trihydroxy-ursoic acid-28-O-β-D-glucopyranoside , 2a. 3a, 19a-trihydroxy-ursoic acid-28-O-β-D-glucopyranoside, 2a, 3a, 19a, 23-tetrahydroxy-ursoic acid, 1a, 3a, 19a, 23-tetrahydroxy-ursoic acid-28-O-β-D-glucopyranoside , 3a, 19a, 23-trihydroxy-ursoic acid.

从珙桐中分离鉴定得到了28种化合物，它们分别是：山奈酚，3-O-β-D-吡喃葡萄糖基-山奈酚甙，3-O-β-D-吡喃半乳糖基-山奈酚甙，槲皮素，3-O-β-D-吡喃阿拉伯糖基-槲皮素甙，3-O-β-D-吡喃半乳糖基-槲皮素甙，没食子酸，4-O-β-D-吡喃半乳糖基-没食子酸甲酯，咖啡酸，咖啡酸甲酯，4-咖啡酰基-(3&α，4&α，5&β)-三羟基鸡纳酸，4-咖啡酰基-(3&α，4&β，5&β)-三羟基鸡纳酸甲酯，5'-咖啡酰基-半乳糖酸，pumiloside，loganic acid，5R，6S，7E-megastima-3-on-7-en-9-ol9-O-β-D-glucopyranoside，2α，3β-二羟基齐墩果酸，2α，3β，23-三羟基齐墩果酸，3α，6α-二羟基齐墩果酸，3β-羟基熊果酸，2α，3α，23-三羟基熊果酸，2α，3β，23-三羟基熊果酸，2β，3β，19α-三羟基熊果酸，2β，3β，19α-三羟基熊果酸-28-O-β-D-吡喃葡萄糖甙，2α，3α，19α-三羟基熊果酸-28-O-β-D-吡喃葡萄糖基甙，2α，3α，19α，23-四羟基熊果酸，2α，3α，19α，23-四羟基熊果酸-28-O-β-D-吡喃葡萄糖基甙，3α，19α，23-三羟基熊果酸。

The inhibitory potency of geranyl gallate is as about six times as that of lauryl gallate on mushroom tyrosinase. Lauryl gallate was determined to be an uncompetitive inhibitor while geranyl gallate belongs to be a mixed-type inhibitor.

没食子酸香叶酯对蘑菇酪氨酸酶的抑制作用比没食子酸十二烷基酯更强，没食子酸十二烷基酯表现为反竞争性抑制类型，而没食子酸香叶酯表现为混合型抑制类型。

Upon initial signal assignment, about 20 chemical constituents in tea were identified, including amino acids, theanine, catechins (EGC, EC, EGCG, ECG and unknown catechins), sucrose, unknown sugars, fatty acids, caffeine, quinic acid and so on. The NMR data were then analyzed by the principal component analysis technique.

检测出约20种物质，包括多种氨基酸、茶氨酸、多种儿茶素表没食子儿茶素(EGC、表儿茶素、表没食子儿茶素没食子酸酯、表儿茶素没食子酸酯和一些未知的儿茶素、蔗糖、未知糖类、脂肪酸、咖啡因等。

The detected phenolic, gallic acid was gradually increased with continuous cropping years increasing, vanillic was steady in soil of different continupus cropping years, ferulic acids had more content in soil of five-year continuous cotton cropping, but remarkably reduced with ten-year continuous cropping.7 It was found that the p-hydrobenzoic, vanillic, gallic acid and ferulic acids in different comentration inhibited/stimulated the spore germination and mycelium growth of cotton verticillium wilt.

没食子酸含量随着连作年限增加在土壤中逐渐增加，香草醛在不同连作年限土壤中含量较稳定，而阿魏酸连作5年土壤中含量最高，连作10年时显著下降。7不同浓度的对-羟基苯甲酸、阿魏酸、香草醛和没食子酸对棉花黄萎病病菌孢子萌发和菌丝生长产生促进或抑制的化感作用。

Alkyl gallates can also low the extent of lipid peroxidation. To investigate the effects of PG and AG on livers that were injured by tetrachloride, we treamed small mice and fed them with different medicines, The conclusion is that AG and PG could scavenge free radical and protect mice livers from injuring by tetrachloride, AG was more effective than PG. 4. 3 The results of experiment for scavenging free radical of alkyl gallate in vitro showed that alkyl gallates can effectively scavenging free radical, but the parent gallic acid showed little effect. This suggested that introducing of hydrophobic group could significantly improve the anti-oxidative ability of gallic acid derivatives at large extent.

在体内没食子酸烷基酯的抗氧化效果大小顺序为：AG＞PG 4.3 体外清除自由基试验表明：没食子酸烷基酯可有效清除自由基，其能力远远大于母体没食子酸，说明引入脂肪链可相当程度上提高没食子酸衍生物的抗氧化能力。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。