没有抑制的

The compound of the invention, which has never been discovered in Antrodia camphorate, can be applied in inhibiting the growth of cancer cells, such as breast cancer, hepatic cancer and prostate cancer; and be used as a pharmaceutical composition to inhibit the tumor growth; or further be applied in prevention of heart and blood vessel disease or dietary supplements for health needs through its antioxidant activity.

该化合物在此之前从来没有被发现，可以应用在抑制癌细胞的生长，如乳腺癌、肝癌和前列腺癌；和被用来作为药剂的组成，以抑制肿瘤的生长；或进一步通过其抗氧化活性应用在预防心脏和血管疾病或营养补充剂。

Here I present evidence that mutation in the gene encoding the catabolite control protein CcpA resulted in a remarkable decrease in mbgA expression from B. megaterium cells grown in the absence or presence of lactose, but had no effect on catabolite repression of mbgA.

在本研究中显示，当在有乳糖及没有乳糖存在时，分解代谢调控蛋白A 的基因突变会造成mbgA基因的表现受到抑制，但是却不会影响mbgA基因的分解代谢抑制作用。

HupA had only a weak inhibitory effect on the voltage-gated soldium channels at a concentration of 1 mM.

HupA对〓和〓的抑制作用与胆碱能系统无关，加入Atropine或Carbacol对HupA的抑制作用没有影响。

The invention provides a parakeratosis inhibitor, a pore-shrinking agent or an agent for preventing/ameliorating rough skin which has a function of inhibiting parakeratosis, shrinking a pore, preventing/ameliorating rough skin or the like, does not have any safety problem such as sensible irritation and has high safety.

本发明提供具有抑制角化不全、收缩毛孔、防止/改善皮肤粗糙等功能，在刺激感觉等安全性上没有问题，安全性高的角化不全抑制剂、毛孔收缩剂或皮肤粗糙防止/改善剂，本发明还提供配合具有上述功能的化合物的皮肤外用组合物。

Picrotoxin reversed the depressive effect of propofol, but it had little or no effect on isoflurane's depressive action.

苦味毒抑制丙泊酚的作用，但是对异氟烷的抑制作用没有效果。

The growth inhibiting rate of T24 cell lines were detected by MTT methods, apoptosis of cells were detected by flow cytometry, the mechanism of apoptosis was analyzed by detecting the protein expression of Bcl-2, Bax, Caspase-9, Caspase-3 and cytoplastic protein Cytochrome C. 4 We injected live T24 cells into the subcutaneous space of nude mice and successfully built up the animal model of bladder carcinoma. The effect of CS-PAA-EPI polymer magnetic microspheres targeting chemotherapy was investigated by HE staining, TUNEL ,tumor weight and volume inhibition rate. Results: 1 TEM revealed that the CS-PAA polymer magnetic microspheres were regular spherical shape,the average diameter was 80nm in dry condition. By controlling the pH value of the medium,polymers had positive or negative zeta potential. VSM showed the CS-PAA polymer magnetic microspheres had superparamagnetic. The diameter of CS-PAA-EPI polymer magnetic microspheres were 200nm in solution by DLS examining,the embedding ratio was 20%,the EPI loading rate was 15%, which was higer than reported in other articles. 2 Raw eye observation found that the rat"s bladder of treatment group was brown color,which meaned the aggregation of iron particles, compared with the control group, iron stain found iron particles were assembled in rat"s bladder of the treatment group, the amount of iron particles in liver and spleen were less obviously.

研究结果：1合成的CS-PAA磁性聚合物微球呈球形，大小均一，TEM测定其干态下粒径为80nm左右，磁化曲线证实具有超顺磁性，具有一定的PH敏感性，固载表柔比星后，水溶液性状稳定，无沉淀物，DLS测定直径约200nm左右，测定载药率为15％，较文献报道高，包封率为20％。2肉眼观察试验组大鼠膀胱表面呈褐色，可见大量的Fe粒子聚集，普鲁士兰染色法显示，试验组大鼠膀胱壁内有大量的Fe粒子，分布至膀胱壁全层，与对照组大鼠相比，试验组大鼠的肝、脾内的Fe粒子聚集量明显降低；HPLC测定结果与Fe染色相同；高剂量磁性CS-PAA-EPI生理盐水组及单纯EPI生理盐水组均在给药后14天出现血肌酐和尿素氮的升高，其他组大鼠血生化指标没有明显变化。3MTT法发现，高、中、低剂量磁性CS-PAA-EPI生理盐水组在外加磁场的协同作用下杀伤T24细胞效应明显高于单纯的EPI生理盐水组，FCM发现试验药物组可引起明显的肿瘤细胞凋亡，试验药物治疗组细胞胞浆内出现了由线粒体释放出的细胞色素C，试验组细胞Bcl-2蛋白减少，Bax蛋白变化不明显，Caspase-3、Caspase-9蛋白受到了激活活化。4高、中、低剂量磁性CS-PAA-EPI生理盐水组的瘤重抑制率和瘤体积抑制率均明显高于单纯的EPI生理盐水组(P＜0.01)，其中高剂量组的抑制率最高。

We measured the results of two groups and examined the change of index. CK fell notably in all study groups, BU fell in sprint and middle-distance race study groups, and HB didn't change in the study.

短跑、中长跑和投掷项目青少年运动员服用活性糖后抑制血清肌酸激酶升高，并且抑制了短跑和中长跑青少年运动员血尿素的升高，但对各项目实验组运动员血红蛋白指标水平没有显著影响。

The majority of BA tested didn′t contract to NE, only a small number of BA contracted to NE but with obvious lower afficacy, lower affinity and tachyphylaxis to NE than RA.

按研究BA和RA平滑肌V〓受体时我们发现，尽管BA和RA在V〓受体的分布上没有差别，但在无钙介质中，AVP引起的收缩在BA则被明显抑制，而在RA则仅被轻度抑制。

The results implied that NO/ROS-induced ABA accumulation come from de novo synthesis pathway rather than degration of conjugated forms. The protein synthesis inhibitor actidone blocked the NO-induced ABA accumulation while having no effects on ROS-induced ABA accumulation, indicating that the action of NO was gene-expression dependent and that of ROS was gene-expression independent. These results suggested that NO may serve as a stress signal in the regulation of ABA-biosynthesis and ROS may serve as substrate in ABA biosynthesis or be involved in the regulation of enzyme activities.

1ABA合成抑制剂fluridone抑制ROS和NO诱导的ABA积累，表明NO／ROS诱导的ABA积累来源于ABA的从新合成而不是已有结合态ABA的代谢；(2)蛋白质合成抑制剂环己亚胺可以抑制NO诱导的ABA积累而对ROS诱导的ABA积累没有影响，说明NO的作用涉及基因表达而ROS的作用与基因表达无关，暗示NO的作用方式可能是作为一种干旱胁迫信号物质参与ABA合成的调节，而ROS则可能参与了相关酶活性的调节或直接参与了ABA合成的底物反应。

In the present study, we report a synergistic interaction between acetylsalicylic acid and caffeine on the inhibition of nociception in a model of peripheral inflammation in rat; on the contrary no interaction have been found on anti-inflammatory effects and peripheral prostaglandin E2 (PGE-2) synthesis inhibition.

在大鼠的周围炎症模型中，发现乙酰水杨酸和咖啡因交互作用抑制伤害性刺激。相反，没有发现抗炎药与外周前列腺素E2(PGE-2)合成抑制有交互作用。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。