沙鼠

Objective To compare the pharmacokinetics of levofloxacin aspartate and other levofloxacin salts in rats.

目的对门冬氨酸左氧氟沙星与其他左氧氟沙星盐在大鼠体内进行了药动学比较。

Objective To evaluate the protection of ulinastatin combined with ofloxacin to diamine oxidase of intestinal mucosa in pyemic rats.

目的 通过检测大鼠肠黏膜中的二胺氧化酶，来评价乌司他丁复合氧氟沙星对脓毒症大鼠肠黏膜的保护作用。

The traditional meal centres around a roast turkey stuffed with breadcrumbs and sage, supplemented by a generous assortment of candied yams topped with baby marshmallows, mashed potatoes with gravy,baked potatoes, potatoes au gratin, baked winter squash, mashed winter squash, jellied salad, green salad, stewed tomatoes, canned green beans, creamed onions, brussels sprouts, cornbread, dinner rolls,cranberry relish, celery, olives, pumpkin pie, apple pie, mince pie, Indian pudding, and ice cream.

传统的饭菜以面包屑和鼠尾草填塞的烤火鸡为中心，此外还有覆以小蘑菇的各种甜薯、土豆泥、肉汁土豆、烤土豆、烤南瓜、南瓜泥、果冻沙拉、蔬菜沙拉、焖西红柿、罐头青豆、奶油洋葱、卷心菜、玉米面包、小圆面包、越橘、芹菜、橄榄、南瓜馅饼、苹果馅饼、肉馅饼、印度布丁和冰淇淋。

We employed HPLC to measure the metabolites of caffeine in the whole blood and calculated the ratio be between the metabolite and caffeine, which was used as index to evaluate the effect of Qingkailing injection on rat CYP1A2 activity in vivo ; We also detected the CYP1A2 and CYP2D6 activity in microsomal reconstituted system by analysis of phenacetin metabolism and dextromethorphan metabolism with HPLC.

通过HPLC法测定全血中咖啡因的代谢率，观测清开灵注射液对大鼠CYP1A2活性的影响；通过HPLC法测定大鼠肝微粒体重组系统非那西丁的代谢比率，确定清开灵注射液对大鼠肝微粒体CYP1A2亚型的作用；测定大鼠肝微粒体重组系统右美沙芬的代谢比率，确定清开灵注射液对大鼠肝微粒体CYP2D6亚型的作用。

Salmonella enterica serovar Typhimurium (S. Typhimurium) is one of the pathogens that cause swine salmonellosis.

鼠伤寒沙氏杆菌(Salmonella enterica serovar Typhimurium)为猪沙氏杆菌症中常见的血清型，临床上会造成猪只肠炎而呈水样下痢。

Results:Arterial blood pressure was apparently decreased by 10 mg/kg losartan intraperitoneally,but heart rate did not change;63.64%(21/33) unit dischargings of habenular neurons was increased in the rate of discharges.

结果：腹腔注射10 mg/kg芦沙坦可显著地降低大鼠动脉血压，但对心率无明显的影响；芦沙坦可使缰核64％(21/33)自发单位放电的放电频率增加。

All rats were killed twelve weeks later, the right kidneies were used for observing pathological change, and the expression of MCP-1 in nephridial tissue were detected by immunohistochemical method. Results (1) Change of morphology: the structure of renal tubule was normal in control group, most glomcruluses were segmented sclerosis in GS group, the renal lesions in valsartan group was minorer than this in GS group.

结果 (1)形态学改变：对照组大鼠肾小管结构正常；肾小球硬化组多数肾小球呈节段性硬化，许多肾小球及肾小管受累；缬沙坦治疗组肾脏病变轻于肾小球硬化组，且肾小球硬化指数明显低于肾小球硬化组(P.01)；(2)MCP-1的表达：对照组肾小管中有少量MCP-1的表达，在肾小球内几乎不表达，在肾小球硬化组和缬沙坦治疗组肾小球及肾小管内表达皆强于正常对照组(P.01)。

Electron-microscopic observation: In stroke-prone spontaneous hypertension group, electron density was found increased in necrotic neurons; moreover, some nuclear membrane lost double-layer structure with ridges broken, even reduced or disappeared, displaying vacuolated changes. In losartan 30 mg/ group and losartan 10 mg/ group, most of neurons displayed basically normal morphology, with neuron chromatin evenly distributed and nuclear envelops regular, but there were still some neurons that had dense chromatin, with ridges broken and reduced.

3组大鼠脑组织电镜观察：易感型自发性高血压组大鼠坏死神经元电子密度增高，有的核膜失去双层结构，嵴断裂、减少甚至消失，呈空泡样改变；氯沙坦30mg/组和氯沙坦10 mg/组大多数神经元染色质分布均匀，核膜规整，细胞形态基本正常；少数神经元核染色质较致密，部分嵴断裂、减少。

Compared with SHRc , after 4 weeks, Pro-EGF mRNA expression level of SHRsv and SHRlv VSMC were significant lower.Conclusions: Valsartan decrease SBP of SHR, inhibit SHR VSMC proliferation, reverse vascular hypertrophy of thoracic aorta and mesenteric artery in SHR, improve the two arteries vasomotion function. Pro-EGF mRNA expression only in SHR VSMC, not in the VSMC of WKY. It indicated pro-EGF gene may play an important role in hypertension advance .

缬沙坦有效降压的同时，抑制SHR大鼠VSMC增殖，逆转其弹性血管和阻力血管的肥厚，明显改善其弹性血管和阻力血管的舒缩功能。pro-EGF mRNA只在SHR大鼠VSMC表达，而在WKY大鼠VSMC没有表达，提示pro-EGF基因可能在高血压的发生发展中起一定的作用，可能是高血压的一个病理机制。

The traditional meal centres around a roast turkey stuffed with breadcrumbs and sage, supplemented by a generous assortment of candied yams topped with baby marshmallows, mashed potatoes with gravy,baked potatoes, potatoes au gratin, baked winter squash, mashed winter squash, jellied salad, green salad, stewed tomatoes, canned green beans, creamed onions, brussels sprouts, cornbread, dinner rolls,cranberry relish, celery, olives, pumpkin pie, apple pie, mince pie, Indian pudding, and ice cream.

传统的饭菜以面包屑和鼠尾草填塞的烤火鸡为中心，此外还有覆以小蘑菇的各种甜薯、土豆泥、肉汁土豆、烤土豆、烤南瓜、南瓜泥、果冻沙拉、蔬菜沙拉、焖西红柿、罐头青豆、奶油洋葱、卷心菜、玉米面包、小圆面包、越橘、芹菜、橄榄、南瓜馅饼、苹果馅饼、肉馅饼、印度布丁和冰淇淋。注意，注意力集中

Neither the killing of Mr Zarqawi nor any breakthrough on the political front will stop the insurgency and the fratricidal murders in their tracks.

在对危险的南部地区访问时，他斥责什叶派民兵领导人对中央集权的挑衅行为。

In fact,I've got him on the satellite mobile right now.

实际上 我们已接通卫星可视电话了