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沙丁胺醇

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METHODS: Eighty guinea pigs were randomized into control group, model group, salbutamol treated group and Maxin liquid treated group. Asthma model s were established by ovalhumin. The changes of eosinophile in bronchoalveolar lavage fluid, thromboxane B2 and 6-Keto-prostaglandin F1a in blood, the airway resistance and the pulmonary compliance were observed by Pap staining, radio-immunity , and pulmonary function test instrument of MIL type specially for experimental animal.

实验设正常对照组、模型对照组、复方麻辛组、沙丁胺醇组,选用豚鼠共80只,采用清蛋白造模,并运用巴氏染色法、放射免疫法、MIL型实验动物肺功能测量仪,分别检测肺泡灌洗液中嗜酸粒细胞数、血浆凝血恶烷(TXB2)、6-酮-前列腺素(6-K-PGF1a)以及清蛋白激发后气道阻力和肺顺应性。

Albuterol inhaler relieved symptoms in 81% of patients.

沙丁胺醇吸入剂使81%的患者症状减轻。

METHODS: Pulmonary function tests were performed in 20 children with asthmatoid bronchitis (2 months-2.5 years of age) before and 30, 60, and 120 minutes after salbutamo and ipratropium bromide inhalation. The indexes of pulmonary function measured included tidal breathing flow volume loop, percent of tidal volume to peak tidal expiratory flow, terminal flows per peak expiratory flow (25/PF), peak tidal expiratory flow, rate of mid-expiratory to mid-inspiratory flow, respiratory rate and tidal volume per kilogram. RESULTS: Before drug inhalation, the descending branch of the TBFV loop was depressed.

20例2个月至2岁6个月的喘息性支气管炎患儿,在吸入药物沙丁胺醇+溴化异丙托品前、吸入后30,60,120min各行一次潮气流速容量环检查,并进行肺功能各项指标比较,包括潮气呼吸流速容量环的形态,反映小气道功能的敏感指标到达潮气呼气峰流速时的呼气量/潮气量,呼出75%潮气量时的呼气流速/潮气呼气峰流速(25/PF),潮气呼气峰流速,反映大气道功能的指标潮气呼气中期流速/潮气吸气中期流速,潮气呼吸状态下的通气功能,包括呼吸频率,每公斤体重潮气量。

While salbutamol blocked AMP/MCh-induced bronchoconstriction, PaO2 and AaPO2 disturbances were partially blocked (AMP, by 46% and 58%; MCh, by 42% and 57%, respectively).

当以支气管舒张剂——沙丁胺醇抑制AMP/MCh诱导的支气管收缩后,PaO2和AaPO2紊乱也有所减轻(AMP,46%和58%;MCh,42%和57%)。

Objective: To compare the effect of ipratropium bromide with sulbutamol, on bronchodilatation in patients with asthma and COPD.

目的:比较溴化异丙托品气雾剂与沙丁胺醇气雾剂分别使用及联合应用对哮喘和COPD患者的支扩作用。

Sand butylamine alcoholic solution union Vitamin K1 oxygen atomization inspiration treatment capillarity bronchitis needs the equipment to be simple, the medication dosage is small, the price is cheap, the clinical curative effect is good, is worth promoting the application.

沙丁胺醇溶液联合维生素K1氧雾化吸入治疗毛细支气管炎所需设备简单,用药剂量小,价格便宜,临床疗效好,值得推广应用。

Methods Produces the fog grain of inspiration treatment sand butylamine mellow, Vitamin K1 and the physiological saline mix solution through the oxygen actuation.

沙丁胺醇﹑维生素K1与生理盐水的混合溶液通过氧气驱动产生雾粒吸入治疗。

METHOD:Salbutamal and carrier particle deposition with various flow rate was characterized by means of a twin stage impinger.

以硫酸沙丁胺醇为模型药物,用双冲程试验仪评价不同的气流速度对吸入型粉雾剂在模拟肺部的沉降量。

The fully inhibited AMP-induced neutrophilia with residual hypoxaemia observed after salbutamol is likely related to beta-agonists acting on both bronchial and pulmonary circulations.

但这些变化都可被沙丁胺醇完全抑制,作者认为这可能是因为β激动剂能同时作用于支气管和肺循环两方面。

Rets: after treated by salbutamol sustained release capsule for 2 wk, nocturnal and daytime symptoms were significantly improved, inhaled β2 adrenoreceptor agonist use was reduced, the integrated effective rate of nocturnal and daytime symptoms was 57% and 60%, respectively, value of fev1 was markedly enhanced and the daily variance rate of pefr was evidently reduced as compared with baseline, the efficacy was similar with that of bambuterol.

结果:沙丁胺醇缓释胶囊治疗2wk后,日夜间症状评分显著下降,按需吸入β2受体激动剂用量显著减少,日、夜间症状综合疗效的有效率分别为57%和60%,fev1较治疗前显著上升,每日pefr变异率较治疗前显著降低,其疗效与班布特罗相似。

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Lao Qiu is the Chairman of China Qiuyang Translation Group and the head master of the Confucius School. He has committed himself to the research and promotion of the classics of China.

老秋先生为中国秋阳翻译集团的董事长和孔子商学院的院长,致力于国学的研究和推广。