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The positive signal of ER and ER mRNA distributed in parenchymal and non-parenchymal hepatic cells, especially near the hepatic centrolobular and periportal areas. Ovariectomy decreased ER level and ER mRNA expression significantly (P<0.05). Hepatic ER and ER mRNA concentration were elevated after treatment with estrogen in both ovariectomy and sham ovariectomy fibrotic groups (P<0.05), and the elevation of ER was correlated with a marked decrease in hepatic damage and fibrosis.

5肝脏ERα及其mRNA基因的表达分布于肝细胞及肝脏非实质细胞,特别以肝脏中央静脉和门脉周围为主;卵巢切除减少ERα及其mRNA基因的表达(P<0.05);雌二醇治疗在肝纤维化和卵巢切除大鼠均提高肝脏ER及其mRNA基因的表达(P<0.05),其增加程度与肝脏组织学损伤、纤维化指标的降低程度以及肝脏胶原沉积减少相平行。

Based on the study of twenty eight cores and thin section observations from the Sangtamu Formation in the south of Tarim River,this paper determines the petrologic features,fossil assemblages and facies distribution with the helps of ray logging and seismic data.

对塔河南20余口钻井进行了详细的岩性观察和室内薄片鉴定,在测井相和地震相识别的基础上,确定了研究区桑塔木组的岩石学特征、古生物组合特征及地层分布特征,进而分析得出其为台地前缘斜坡和内陆棚沉积环境。

Phylogenetic analysis showed that the proteobacteria were the dominant group both in the sediments and waters,γ-proteobacteria and δ-proteobacteria were dominant in the sediments,α-proteobacteria were dominant in the water. However, all subphyla of proteobacteria presented phylogenetical divergence at the two sites.

各站位中主要为变形菌门,沉积物中γ-Proteobacteria和δ-Proteobacteria亚门占优势,水中则以α-Proteobacteria亚门占优势,但各亚门微生物在两个站位中存在明显系统发育学分歧。

Objectives In order to investigate how does King's Brain pill work or mechanism of King's Brain pill effective in treating AD clinically, we observed effects of extract of King's Brain on neuronal and vascular lesions induced by Aβ combining with praxiology and neuropathology.

目的 运用现代分子神经病理学和行为学技术,围绕炎症假说、淀粉样蛋白瀑布流假说,以神经元和脑血管为保护目标,着眼于AD的关键病理机制Aβ(β淀粉样蛋白沉积和淀粉样血管病变)及其代谢,开展中药补肾活血化痰复方制剂金思维对损伤的神经元和血管的保护作用机理研究,从而探讨其防治老年性痴呆的机理。

By studying reservoir rock characteristics, diagenesis and physical property, investigation showed that there were distributary channel, branch channel, mouth bar, distal bar, sand sheet, lakeshore, shallow lake and limestone flat . we concluded that the reservoir of N1~N21 is low porosity and permeability reservoir with the types of primary porosity and secondary intergranular porosity, which is in the early diagenetic stage B into the late diagenetic stage A subperiod. The role of effecting reservoir physical property is deposition, cementation, dissolution and tectonic rupture. After researching of reservoir, we divided it into three categories and division the favorable facies belt and relatively favorable. We think that the favorable facies belt is braided river delta front and partly shallow lake in east of the Fault Ⅶ. favorable reservoir is in the first and the second class.

进一步研究了本区碎屑岩储层的岩石学特征、成岩作用特征、物性特征,研究认为该区储集体类型有分流河道砂体、分支河道砂体、河口坝、远砂坝、席状砂砂体、滨湖砂滩、浅湖砂坝砂体及灰坪;N1层属于低孔、特低渗储层,孔隙类型以原生、次生粒间溶孔为主;分析了影响储层物性的因素主要为沉积作用、胶结作用、溶蚀作用和构造破裂作用;进行了储层评价与有利相带预测,将储层分为三类并划分了有利区带、较有利区带,认为Ⅶ号断层以东的辫状河三角洲前缘亚相和部分浅湖亚相是N1的有利储集相带,储层以Ⅰ、Ⅱ类为主。

The area of exploration is 120km2.The lower strata of Es2 are terraneous basin sediments. The analytic method of traditional sequence stratigraphy theory is stemmed from sea sediment studies, and how to apply the theory to the exploitation of land sediment.

该油田古近系沙河街组沙二下亚段地层属陆相断陷湖盆沉积,传统的层序地层学分析方法起源于海相地层应用中,如何将其应用到陆相开发方面一直是人们比较关注的一个问题。

The field survey, sampling, testing and collection of the geological and hydrogeological data were done for the description of evolutional geological structure and sedimentation and division and definition of water-bearing system and hydrogeological age and hydro-pressure system and study of the vadose field and chemical field. By establishing the rammer numerical model, the sandy mudstone thickness recovery model, water-rock interaction particle translative simulation and hydrogeochemical simulation, and using geological statistics, analogism and complex analysis method, water circulation and water exchange of each layer in each study stage have been researched, The results show the regularity of the vadose field evolution in different stages.

本项以野外调查、采样测试和搜集的地质、水文地质大量第一性资料为依据,在论述盆地的地质构造演化、沉积演化的基础上,以含水系统、水文地质期和水压系统类型的划分和定位为研究的切入点,渗流场、化学场为研究主线,通过建立压实数学模型、砂泥岩恢复厚度数学模型、水岩作用物质成分转移的实验模拟、水文地球化学模拟、地质统计法、类比法、综合分析法等方法,模拟计算了各研究层在各研究时期水循环特点和水交替强度,揭示了各研究层渗流场在地史进程中形成演化的规律性。

ZHAO Yede*,HE Qinglian.Department of Plastic Surgery, Navy 411 Hospital, Shanghai 200081Objective To investigate the expression level and intracellular distribution of calreticulin in hypertrophic scar-derived fibroblastsand normal skin-derived fibroblasts.

增生性瘢痕(Hypertrophic scar, HS)作创伤及外科手术后常见且十分棘手的皮肤组织疾病,瘢痕组织内成纤维细胞异常活化和细胞外间质过度沉积既是HS的重要组织学特征,也是HS发生、发展的物质基础。

After detail field inspecting, combined with the deep indoor research result, the author regarded that those deposits, which districted in West Kunlun Mountain Region , are belong to Mississippi Valley Type Lead-Zinc deposits.

本文运用区域成矿学理论从沉积建造、岩浆活动、构造演化以及区域地球物理场和地球化学场特征等方面系统地阐述了西昆仑地区(特别是奥依塔格—库尔良晚古生代裂陷盆地)的成矿地质条件。

The main fruits and cognition are as follows:1 .On the base of collecting and neatening some data about this area, using sequence stratigraphy theory and the traditional method of cycle correlation, combining core observation with well log interpretion, set up subtle stratum contrasting framework section, and Chang-6 formation is divided nine substratums from top to bottom.

本次研究所取得的主要成果及认识有: 1、在对研究区已有取心井段的相关资料进行收集与整理的基础上,应用层序地层学理论与传统沉积旋回小层对比方法,结合岩心观察与测井解释,建立以小层为单位的精细地层对比骨架剖面,将研究区长6油层组自上而下细分为9个不同级别的小层。

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在美国,慢性酒精中毒,肝炎是最常见的。

If you have any questions, you can contact me anytime.

如果有任何问题,你可以随时联系我。

Very pretty, but the airport looks more fascinating The other party wisecracked.

很漂亮,不过停机坪更迷人。那人俏皮地答道。