汗腺的

In summary, our results indicate that hypohidrosis is a frequent adverse effect in children with topiramate therapy. Younger age and hot weather rather than drug dosage are independent risk factors for topiramate-associated hypohidrosis. The resultes also rule out the possibility that topiramate act on its known mechanisms of action, such as potentiating GABA activity at GABAA receptors and antagonizing the AMPA/KA subtype of glutamate receptor in the secretory cells of sweat glands to inhibit sweat secretion. Our data also suggest that topiramate impairs sudomotor function in mice and leads to a significant reduction in AQP5 expression in sweat glands of anhidrotic mice, thus raising the possibility that dysregulation of AQP5 may contribute to topiramate related hypohidrosis. CA inhibition may not be an important contributor since CA II expression and CA activity was intact in anhidrotic mice treated with topiramate.

综合全部实验结果，本研究提示：夏季和低龄是托吡酯引起泌汗障碍的主要危险因素，而托吡酯剂量对泌汗功能的影响较小；托吡酯可以抑制小鼠汗液的分泌，小鼠的年龄并不影响这种抑制作用，但托吡酯对小鼠体温无明显影响；托吡酯并不是通过对GABAA受体及AMPA和KA两种谷氨酸受体亚型的作用而在汗腺分泌细胞抑制泌汗；托吡酯不影响汗腺形态及Na，K-ATP酶活性；汗腺分泌细胞的AQP5功能失调可能与托吡酯引起的泌汗障碍密切相关，而碳酸酐酶抑制作用并不是泌汗功能损害的主要原因。

In summary, our results indicate that hypohidrosis is a frequent adverse effect in children with topiramate therapy. Younger age and hot weather rather than drug dosage are independent risk factors for topiramate-associated hypohidrosis. The resultes also rule out the possibility that topiramate act on its known mechanisms of action, such as potentiating GABA activity at GABAA receptors and antagonizing the AMPA/KA subtype of glutamate receptor in the secretory cells of sweat glands to inhibit sweat secretion. Our data also suggest that topiramate impairs sudomotor function in mice and leads to a significant reduction in AQP5 expression in sweat glands of anhidrotic mice, thus raising the possibility that dysregulation of AQP5 may contribute to topiramate related hypohidrosis.

综合全部实验结果，本研究提示：夏季和低龄是托吡酯引起泌汗障碍的主要危险因素，而托吡酯剂量对泌汗(来源：A44B8787C论文网www.abclunwen.com)功能的影响较小；托吡酯可以抑制小鼠汗液的分泌，小鼠的年龄并不影响这种抑制作用，但托吡酯对小鼠体温无明显影响；托吡酯并不是通过对GABAA受体及AMPA和KA两种谷氨酸受体亚型的作用而在汗腺分泌细胞抑制泌汗；托吡酯不影响汗腺形态及Na，K-ATP酶活性；汗腺分泌细胞的AQP5功能失调可能与托吡酯引起的泌汗障碍密切相关，而碳酸酐酶抑制作用并不是泌汗功能损害的主要原因。

Methods Vacuole incidence of axillary sweat gland was determined by observing the histolomorphological changes of vacuole to evaluate the diaphoretic function.

方法采用组织形态学方法，以大鼠腋窝部皮肤汗腺的空泡发生百分率作为评价发汗强度的指标，观察麻黄汤不同配伍给药后30 min对大鼠的发汗作用。

Methods Through digesting human skin with collagenase type Ⅱ, cells of human eccrine sweat gland were isolated.

通过酶消化法分离人皮肤汗腺，微量加样器在倒置显微镜屏视下吸取游离的汗腺组织移入Hank平衡盐溶液，经纯化后予以原代培养。

Incidence rate, clinical characteristic and risk factors for hypohidrosis were analyzed to provide clues for possible mechanisms underlying topiramate-induced hypohidrosis.

继而，建立托吡酯引起泌汗障碍的小鼠动物模型，以明确托吡酯是否能够抑制小鼠汗腺的分泌及其发生规律(来源：ABC论文ae网www.abclunwen.com)和影响因素。

According to the rule of treatment of axillary osmidrosis, we used subcutaneous pruning by fold incision and CO2 laser vaporization removed apocrine gland to radical excision of axillary osmidrosis. This is an ideal method to treat axillary osmidrosis because of its credible effect, no special requirement to instruments and simple operation, and it can be widely used.

采取手术修剪皮下大汗腺与CO2激光汽化真皮层内的大汗腺相结合，符合彻底去除腋窝大汗腺治疗腋臭要求，实践证明该方法疗效肯定，且设备条件要求低，操作简单，不失为一种较为彻底根治腋臭的方法，值得临床推广应用。

SGs are innervated by sympathetic postganglionic axons, which, in contrast to the ordinary sympathetic innervation, use acetylcholine as the principal neurotransmitter.

人类在高温或运动时的热驱散主要依靠小汗腺的蒸发而带来的散热作用。

The sweat gland of human being consists of eccrine gland and large sweat gland which is the root of body odor.

人体汗腺分小汗腺与大汗腺大汗腺是产生狐臭的根源。

The depressed sudomotor function of mouse foot pad sweat gland related TPM have no association with the development and innervation of sympathetic nerve that supplies mouse sweat gland.

2TPM导致的泌汗障碍没有影响到小鼠汗腺的面积大小和形态、超微结构。

Once improve what exercised sweat gland to excrete a function, classics sweat fluid is excreted took away much quantity of heat not only, and still make " loss of appetite and weight in summer " disease as sweat a prediction of a person's luck in a given year.

一旦改善并锻炼了汗腺的排泄功能，经汗液排泄不仅带走了大量的热量，而且还使&苦夏&症随着汗水一起流失。

I didn't watch TV last night, because it .

昨晚我没有看电视，因为电视机坏了。

Since this year, in a lot of villages of Beijing, TV of elevator liquid crystal was removed.

今年以来，在北京的很多小区里，电梯液晶电视被撤了下来。