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Ping chuan-fang prescription is carefully composed accordingly. The clinical investigation shows that PCHF can not only alleviate symptoms and physical sign of the patients effectively, but also shorten the course of disease and obviously can not only alleviate symptoms and physical sign of the patients effectively, but also shorten the course of disease and obviously improve the pulmonary function of the patient. The animal experiment showed that PCHF can prolong the asthmatic time and low the concentration of WBC, EOS, IL-4, ET-1 in the blood and BALF. It can restrain the collection of EOS in the lung and relieve the inflammation caused by EOS. It also can cut down the secretion of the respiratory air-way and relieve the obstruction of it.

动物实验表明:平喘方能明显延长卵蛋白造模大鼠的引喘潜伏期,且与氨茶碱对照有非常显著性差异(P<0.01);能降低哮喘模型大鼠血浆及肺泡灌洗液中白细胞、嗜酸性粒细胞及IL-4、ET-1的含量;能抑制肺局部EOS的聚集,明显减轻由EOS浸润引起的慢性变应性炎症反应;能减少气道分泌物,减轻细支气管及小血管管壁的增厚,减轻周围组织的水肿,从而减轻气道的阻塞,最终改善肺通气,缓解喘息症状。

Ping chuan-fang prescription is carefully composed accordingly. The clinical investigation shows that PCHF can not only alleviate symptoms and physical sign of the patients effectively, but also shorten the course of disease and obviouslycan not only alleviate symptoms and physical sign of the patients effectively, but also shorten the course of disease and obviously improve the pulmonary function of the patient. The animal experiment showed that PCHF can prolong the asthmatic time and low the concentration of WBC, EOS, IL-4, ET-1 in the blood and BALF. It can restrain the collection of EOS in the lung and relieve the inflammation caused by EOS. It also can cut down the secretion of the respiratory air-way and relieve the obstruction of it.

动物实验表明:平喘方能明显延长卵蛋白造模大鼠的引喘潜伏期,且与氨茶碱对照有非常显著性差异(P<0.01);能降低哮喘模型大鼠血浆及肺泡灌洗液中白细胞、嗜酸性粒细胞及IL-4、ET-1的含量;能抑制肺局部EOS的聚集,明显减轻由EOS浸润引起的慢性变应性炎症反应;能减少气道分泌物,减轻细支气管及小血管管壁的增厚,减轻周围组织的水肿,从而减轻气道的阻塞,最终改善肺通气,缓解喘息症状。

RESULT: 1.Ouabain act on lens sodium-pump,under the LM,lens anterior capsular membrane discontinuous,epithelium cells clustered,occluding zonule seperated,lens fiber layers fractured.Under the EM,cells totally hollowed,mitochondria swelling,myelin figure appeared.RT-PCR examine the expression condition of αsubunit of sodium pump on mRNA level,α1、α2 and α3-isoform are all decreased.2.Digoxin act on lens sodium-pump,under the LM,lens cell oedema,linkage distructed,extensive exfoliation.Under the EM,plasma appeared little half-transparant hollow region,mitochondria swelling and ridge disappeared. RT-PCR examine,α1、α2 and α3-isoform are all decreased.3.Amphotericin B act on lens sodium-pump,under the LM,lens epithelium cells linked tightly,arranged in-line,lens fiber layers arranged tightly and regularily.Under the EM,abbundant cellular organes,exuberant cells function indicated. RT-PCR examine the expression condition of αsubunit of sodium pump on mRNA level,α1 and α3-isoform are increased significantly,demonstrated isoform-specific action.4D-thyroxine act on lens sodium-pump,under the LM,lens plasmalemma integrated,cells arranged tightly and regularily.Under the EM,nucleus fission appeared,desmosome half-desmosome and tensile microfilaments linked the cells. RT-PCR examine,α2 and α3-isoform are increased, also demonstrated isoform-specific action.5.Vitamin E act on lens sodium-pump,under the LM,lens anterior capsular membrane continuous and smooth,epithelium cells tightly linked,lens fiber layers appearede hollow region occasionally.Under the EM,lateral membrane high density belt appeared,abundant nucleolus. RT-PCR examine,onlyα1-isoform are increased, demonstrated significantly isoform-specific action.6.DMSO act on lens sodium-pump,under the LM,lens anterior capsular membrane slightly thicker,cells linkage partly distructed.Under the EM,plasmalemma denaturation,mitochondria swelling.RT-PCR examine,α1、α2 and α3-isoform are all altered slightly and haven't significant meanning.

结果:1、哇巴因作用于晶状体钠泵后,光镜下晶状体前囊膜断裂、上皮细胞聚积、闭合连接分离、纤维板层裂隙,电镜下全层细胞空泡化、线粒体肿胀出现髓样结构,RT-PCR法检测晶状体钠泵α亚单位α1、α2及α3三种重整异构体在mRNA水平的表达均减弱。2、地高辛作用于晶状体钠泵后,光镜下晶状体细胞水肿、细胞连接破坏、广泛剥离,电镜下胞质见少许半透明空化区、线粒体肿胀嵴消失,RT-PCR法检测晶状体钠泵α亚单位α1、α2及α3三种重整异构体在mRNA水平的表达均减弱。3、两性霉素B作用于晶状体钠泵后,光镜下晶状体上皮细胞紧密连接、线状排列、纤维板层紧密规整,电镜下细胞器丰富、细胞功能旺盛,RT-PCR法检测α1及α3表达显著增强、具有一定的重整异构作用特异性。4、D甲状腺素作用于晶状体钠泵后,光镜下晶状体质膜完整、细胞排列紧密规整,电镜下胞核见分裂像、细胞间有桥粒、半桥粒及张力微丝,RT-PCR法检测α2及α3表达均增强、亦有一定的重整异构作用特异性。5、维生素E作用于晶状体钠泵后,光镜下晶状体前囊膜连续光滑、上皮细胞紧密连接、纤维板层偶见空化,电镜下囊侧膜内有高电子密度带、细胞核仁丰富,RT-PCR法检测仅有α1的表达显著增强、具有极强的重整异构作用特异性。6、二甲基亚砜作用于晶状体钠泵后,光镜下晶状体前囊膜轻度增厚、细胞连接部分破坏,电镜下质膜变性、线粒体肿胀,RT-PCR法检测晶状体钠泵α亚单位α1、α2及α3三种重整异构体在mRNA水平的表达无显著改变。

While carotid endarterectomy is performed in the emergency setting of an acute ischemic stroke that occurs postcarotid endarterectomy, emergency carotid endarterectomy is not generally done because there are concerns for complications of brain edema and hemorrhagic transformation due to reopening of the vessel and reperfusion of the stroke area.

很少有 &有效性的手术治疗急性缺血性中风的信息&虽然颈动脉内膜切除术是在急性缺血性中风发生 postcarotid 剥脱的紧急情况制定的,但紧急颈动脉内膜切除术一般不这样做,因为人们担心由于血管再通和缺血区域再灌注而致脑水肿和出血的并发症。

Thereby it demonstrated that resisting the damage of oxygen free radial. antigoniz- ing the overloading of calcium, relieving cerebral edema and regulating the imbalamce between 6—Keto—〓 and 〓 are the key link of NMTI in Curing ischemia/reperfu- sion injury and inhibiting the progress of the disease. The mechanism of NMTI at brain protecting also lies there. The results Provided strong basement on which NMTI was studied furtherly and widely used for curing certbral ischamia and reirrigate injury in clinical practice.

从而表明抗自由基损伤,拮抗钙超载,减轻脑水肿,调节前列腺素与血栓素失衡状态是脑脉通注射液防治脑缺血再灌注损伤,阻止病程进展的主要作用环节,也是脑脉通注射液发挥脑保护作用的重要机制所在,为脑缺血再灌注损伤的治疗和脑脉通注射液的进一步研究及临床推广应用提供了一定的依据。

The path-physiological mechanism of ICH is complicated, which includes the high intracranial pressure caused by hematom mechanical pressure, the lesion by the decrease of regional cerebral blood flow surrouding the hematom, even regions adjacent to the hematom, Meanwhile, the materials released from hematom including ferrohemoglobin, thrombase, plasma protein and platelet, leucocyte, glusate not only directly injury neurons but also blood brain barrier.

脑出血的病理生理学机制复杂,其中包括血肿的机械压迫所造成的持续的脑缺血性损害;血肿分解后产生的血红蛋白、凝血酶、血浆蛋白、血小板和白细胞、谷氨酸、自由基等毒性物质不仅可直接损伤神经元,而且可损害血脑屏障加重脑水肿。

In an attempt to evaluate the safety and efficacy of Healon in trabeculectomy, 20 eyes with Healon and 20 eyes without Healon injection after trabeculectomy are compared. Trabeculectomy using Healon will not induce transient rise of intraocular pressure. By filling the anterior chamber with Healon, a tamponing effect results which will maintain a deep chamber and reduce complications such as flat anterior chamber, choroidal detachment and striate keratopathy in the early postoperative period. In long-term evaluation there is no difference in pressure control, conjunctival scarring and corneal endothelial cell loss between Healon group and Non-Healon group.关键词 trabeculectomy , flat anterior chamber , choroidal detachment , intraocular pressure

为了评估Healen在小梁切除术中之疗效及安全性,选20位接受小梁切除术者,同时注射Healon於前房为实验对象,另20位接受传统小梁切除术为对照组,发现使用Healon并不会引起一过性眼压上升的现象,Healon注入前房,产生填塞作用,最大的好处是可以维持前房深度,减少术后合并症如前房消失,脉络膜剥离及角膜水肿等,然长期追踪,对於降眼压的幅度,不因使用Healon而可达到低眼压状态,也不会减少结合膜瘢痕化而促进房水引流,然Healon系一无毒,无炎性,无抗原性高黏稠性的物质,不因使用而发生炎性反应,同时有保护角膜内层细胞的功能。

It is now known that seere hypoxia-ischemia may not cause immediate cell death, but may precipitate a complex biochemical cascade leading to the delayed deelopment of neuronal loss. These phases include a latent phase after reperfusion, with initial recoery of cerebral energy metabolism but EEG suppression, followed by a secondary phase characterized by accumulation of cytotoxins, seizures, cytotoxic edema, and failure of cerebral oxidatie metabolism from 6 to 15 h post insult.

现在认识到严重的局部缺氧有可能不立即引起细胞坏死,但是可能促成一种复杂的生化级联反应,这可能导致神经元丢失,进而导致延缓发育,这些时期包括再灌注后的潜伏期,该期出现早期的脑能量代谢复苏但脑电图却呈抑制状态,紧接着第二期表现为损伤后6-15个小时细胞毒素,癫痫,细胞毒性水肿,脑氧化功能衰竭的累积。

The pathogen of gas gangrene mainly exist and live in local place, and seldom enter blood system to cause blood poisoning, but than can form lots of toxins, this toxins can harm blood system, kidney system, and also the tissue can putrescence and the wound will enlarge step by step, all tissue putrescence and toxin can make these bacteria easier to live and reproduce, all these situation if not being control in time will lead a serious situation that multiple organs dysfunction and then died

气性坏疽的病原菌主要在伤口内生长繁殖很少侵入血液循环引起败血症。产气夹膜杆菌产生α毒素、胶原酶透明质酸酶、溶纤维酶和脱氧核糖核酸酶等,红细胞破坏引起溶血血红蛋白尿、尿少、肾组织坏死水肿、液化,肌肉大片坏死使病变迅速扩散、恶化。糖类分解产生大量气体使组织膨胀;蛋白质的分解和明胶的液化,产生硫化氢,使伤口发生恶臭由于局部缺血,血浆渗出,及各种毒素的作用伤口内的组织和肌肉,进一步坏死和腐化,更利于细菌的繁殖使病变更为恶化。

The results showed that the sheep had fibrinous pneumonia and lymphocyte interstitial pneumonia, which were typical pathologic changes of this disease. Remarkable changes were observed in the lung: fibrinous exudates, infiltration of inflammatory cells, pleura thickening, interstitial edema, hemorrhage and formation of thrombiand lymph clot. The heart, liver and kidney had different degeneration degree. Reactive hyperplasia presented in bronchales lymphonodi.

结果发现该病例具有胸膜肺炎的典型病理变化,呈现纤维素性肺炎和淋巴细胞性间质肺炎,纤维素性物质的渗出和炎性细胞的浸润很明显,肺胸膜增厚,同时在肺间质还可见水肿、出血、血栓和淋巴栓的形成;另外心、肝、肾也均有不同程度的变性,淋巴结呈反应性增生。

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It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发,分析对称连杆曲线上鲍尔点的产生条件,提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品,年生产总值3000万美元,产品价廉物美、选料上乘、质量保证,深受国内外客户的青睐

The eˉtiology of hemospermia is complicate,but almost of hemospermia are benign.

血精的原因很,以良性病变为主。