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Few research was involved in the change and gene expression of microbial population and role of functional protein in the matrix of dental plaques in the pathogenesis and development of disease.

随着功能基因组学、微生物非培养方法、二维电泳、生物质谱等技术的出现,使得从整体水平对菌斑中细菌的生物多样性、生物膜状态和浮游状态下的基因表达以及蛋白表达的差异进行研究成为可能。

Their results show that locusts behaving the most gregariously (in swarm-mode) had approximately three times more serotonin in their systems than the calm, solitary locusts.

他们的结果显示,那些处于最为集结状态的蝗虫比那些处于平静独处状态的蝗虫,其体内的5-羟色胺水平要高出近3倍多。

In the experiment, an approach was made to the cause of DRP and the mechanism of it's prevention and treatmend by acupuncture. The experimental results indicated that in rat with diabetes,(1) plasma TXB2 and the ratio of TXB2 to 6-keto-PGF1α increased obviously, suggesting hyperfunction of platelet and injury to endothelial function, which tend to result in thrombosis;(2) erythrocytic filtration index increased remarkably, suggesting erythrocytic transforming and oxygen carring hypofunction, which is one of the factors leading to retinal anoxia;(3) hyperglycemia persisted, which is related to the thickening of basilar membrane of and the decrease of mural cell of retinal blood vessels;(4) serum growth hormone rose notably, which is not only one of the important factors causing basilar membrane thickening but also promotes the synthesis or Von Willebrand Factor that participates in a tendency to thrombosis.

本实验对糖尿病性视网膜病变(Diabetic Retinopathy,DRP)的成因以及针刺防治DRP的作用机理进行了探讨,实验结果表明:糖尿病大鼠(1)血浆TXB2及TXB2/6-ket0-PGF1α比值均显著升高,提示其血小板机能亢进,内皮细胞功能损伤,具有血栓形成倾向;(2)红细胞滤过指数(Filtration Index,IF)显著增高,提示其红细胞变形能力低下,携氧运行功能降低,是造成视网膜缺氧状态的因素之一;(3)呈持续高血糖状态,与视网膜血管基底膜增厚及管壁细胞减少有关;(4)血清生长激素(Growth Hormone,GH)水平明显升高,既是导致基底膜增厚的重要因素之一,又促进VWF合成,参与血栓形成倾向。

The behavioral choice depends on the pattern of neural input to the command centers, and on the modulatory state of the animal (e.g., hormonal state, or motivational state, etc.).

行为的选择依赖于指挥中心的神经输入,以及动物的调节状态(例如,激素水平或者动机状态等)。

The supply chain integrates a status":This research investigates the status of the supply chain integration with the standpoint of the organization function and the closed path standpoint; Function standpoint :Enhance the enterprise internal function, promote supply chain integration worth, include a green environmental protection supply chain, supply chain security etc. value activity, carry on horizontal and vertical to integrate a promotion project; Closed path standpoint :Get into an international marketing by the integration value of the closed path, the different industry that creates a supply chain to totally use closed path and look for to have a closed path resource carries on an alliance and develops the value of the closed path integration."

供应链整合状态」:本研究以组织功能观点及通路观点来探究供应链整合状态;功能观点:强化企业内部功能,促进供应链整合价值,包含绿色环保供应链、供应链安全等价值活动,进水平与垂直整合推动计画;通路观点:以通路的整合价值进入国际市场销,建供应链共用通、寻求具有通资源的业进盟,发挥通路整合价值。

Starting from the main meteorological factors impacting vibration of overhead line, the impact of conductor tension variety on self-damping feature of conductors is analyzed according to state equations of overhead line, and by use of energy balance principle the variation of vibration level is calculated and the vibration life under different meteorological conditions are obtained.

文章提出了一种基于短期测量数据评估线路全年振动状态和寿命的方法,从气象影响线路振动的主要因素出发,根据导线的状态方程分析导线因张力变化对导线自阻尼特性的影响,并采用功率平衡法计算出振动水平的变化,得到了不同气象条件下的振动寿命。

Both thrombophlebitis and pyemia are typical examples of hypercoagulatory states caused by inflammation.In fact,inflammation had been showed as an important reason that lead to thrombotic events in a lot of studies of atherosclerosis and heart failure.Further investigations have showed a prothrombotic state with blood hypercoagulation,platelet activation,damaged atrial endothelium and atrial blood stasis in AF,while these changes are due to the AF itself,or coexistent cardiovascular risk factors remains a matter of debate.

虽然房颤时高凝状态和血小板功能激活是非常明确的,是造成房颤血栓形成的重要原因之一(其他两个原因包括心房血流淤滞和内皮功能损害),但是房颤高凝状态和血小板功能激活与炎症水平的关系,尽管对指导采取何种预防血栓形成的治疗策略意义很大,目前已有的研究较少涉及这方面,国内外几乎没有相关的研究报告。

According to the reality of dynamic alliance in China, the partner appraisement index system is established. The partner appraisement indexes are classified into several subindexes: enterprise resource, operation status, management level, geographical location, service, and enterprise culture, each subindex can be subdivided further.

结合我国企业动态联盟的现状,提出了企业动态联盟伙伴选择的评价指标体系,将动态联盟的伙伴评价指标分解为企业资源状态、企业经营状态、企业管理水平、企业地理位置、售后服务和企业文化融合六个分指标,并将每个分指标细化为若干下级指标。

In aim at the complicity and high-dimensional state-space for the controlled system, it simplifies the calculation of geometric polytope by optimize with ellipsoidal approximate techniques, and the robust control effectiveness near to the optimal.

本论文所提示的基于几何理论的约束非线性控制算法是建立在最大输出允许集合的基础上,运用状态空间的有界子集表达鲁棒时优离散时间控制问题的价值函数,通过逆序计算该价值函数的水平集合,求得其所需的控制量,针对被控系统的复杂性及高维状态空间问题,运用椭球近似技术予以优化,使得几何多面体的计算得以简化,且鲁棒控制效果接近最优。

Reactive oxygen species causing DNA oxidative damage comes from two kinds of ways:one is from cellular normal physiological metabolism;the other is from outer environment.Redox-sensitive green fluorescent protein was expressed in Saccharomyces cerevisiae.Recombinant cells were evaluated in monitoring the changes in the redox state of living cells when challenged with toxicologically relevant metal ions NaAsO_2 or Pb(NO_3)_2 by measuring emission intensity at 510 nm with a Hitachi F6500 fluorescence spectrophotometer,roGFP expressed in yeast responded not only to typical membrane-permeant oxidants H_2O_2 and reductants DTT,but also to toxicological metal ion-induced intracellular redox changes in a dose-dependent manner.Moreover,exposure of yeast cells to NaAsO_2 or Pb(NO_3)_2 at concentrations that induced redox changes reported by roGFP caused up to 2~3 fold increases in DNA mutation frequency.This mutagenic effect was largely caused by oxidative stress since blocking the production of hydryl radicals with thiourea significantly reduced the mutation rate as well as delayed the cell death.

本文将对氧化还原状态变化敏感的绿色荧光蛋白roGFP1-R12,在酵母细胞中实现了多拷贝强表达;荧光扫描经强氧化剂H_2O_2和还原剂DTT以及环境中重金属NaAsO_2或Pb(NO_3)_2处理后的酵母细胞悬液,测定510 nm处的荧光发射强度结果显示,表达的绿色荧光蛋白对氧化还原水平敏感,且在510 nm处的荧光强度与一定的重金属浓度呈正相关,即roGFP1-R12在510nm处的荧光发射值随重金属浓度的增高而增强,从而说明重金属对细胞的毒性在一定程度上很可能是通过破坏细胞内的氧化还原平衡发生作用;同时通过该绿色荧光蛋白对胞内氧化还原状态变化的响应情况可以来实时检测环境中的重金属;遗传学的点突变频率及致死率实验数据表明,重金属能导致菌体的点突变频率和致死率升高,且活性氧的清除剂巯基脲能明显降低这种点突变和致死率,说明由重金属引发的这种点突变和致死效应在很大程度上是依赖于重金属对细胞诱导产生的氧化胁迫。

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This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。

There is no differences of cell proliferation vitality between labeled and unlabeled NSCs.

双标记神经干细胞的增殖、分化活力与未标记神经干细胞相比无改变。