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Lyar was found to interact with Nucleolin, another important nucleolar protein.

Lyar表达水平的的下调能导致ES细胞中Nucleolin的蛋白水平明显下降,而mRNA水平无明显变化。

Results showed sTGC-CM, which is similar with the effect of hTGC-CM, was able to induce human DPSCs to make odontoblastic changes as indicated by remarkable morphological changes, increased proliferation ability, higher multipotential and colony forming capability, and expression of some odontogenic markers in gene and protein levels,such as DSP, DSPP, DMP1, BSP, OCN, OPN.

结果表明:人牙髓干细胞经过一定时间的猪牙胚条件培养基诱导后,能在细胞形态上和细胞周期上发生改变,能具有更高的克隆形成能力和多向分化能力,能维持更好的干细胞特性,具有更强的增殖能力,表达更高水平的碱性磷酸酶,免疫组化和RT-PCR提示诱导后的牙髓干细胞能在蛋白水平和基因水平表达出一些牙向分化的标志,如DSP、DSPP、DMP1、BSP、OCN、OPN等。

Methods 120 SD rats were divided randomly into blank group, model group, Baoliezhi control group and Qianliening granule groups with different doses. The models were established with hypodermic injection of testosterone propionate at 4 mg/kg after orchiectomy, at the same time, these rats were gastric perfused with different drugs respectively for 30 days. The body weight, prostate weight, prostate index, morphological changes, the level of T and E2 were measured. Results The body weight in model group was significantly lower than that in control group (P.05), the prostate weight and index were obviously higher than that in control group (P.01). The prostate weight and index were decreased significantly in Qianliening granule groups with meddle and high doses (P.01), the level of testosterone was increased significantly and E2 was decreased obviously in Qianliening granule group with high doses.

将雄性SD大鼠60只,随机分成空白组、模型组、保列治治疗对照组、前列宁颗粒低、中、高剂量组,采用丙酸睾丸酮皮下注射引起大鼠前列腺增生模型,连续给药30d后,观察6组动物体重前列腺湿重前列腺指数前列腺组织形态血清睾酮雌二醇(E2)水平的变化结果模型组大鼠体重较正常组明显减轻(P.05),而前列腺重量和前列腺指数明显升高(P.01);前列宁颗粒中、高剂量组的前列腺重量和前列腺指数明显下降(P.01);前列宁颗粒高剂量组可明显升高大鼠血清T水平,降低E2水平,使T/E2比例升高。

These changes were prevented by genistein (a protein tyrosine kinase inhibitor) and antioxidant N-acetyl-L-cysteine, but promoted by sodium orthovanadate (a protein phosphatase inhibitor), which were administered to the SD rats 20 min before ischemia.

进一步的研究表明,缺血前20 min腹腔注射给药,然后缺血30 min,发现蛋白酪氨酸激酶抑制剂染料木黄酮和抗氧化剂N-乙酰半胱氨酸能显著地抑制核内STAT3的磷酸化水平及DNA结合活性的增加(磷酸化水平从2.3和2.5倍分别降为1.2和1.4倍, DNA结合活性则从2.8和3.7倍分别降为1.1和1.5倍),而蛋白酪氨酸磷酸酶抑制剂矾酸钠则能明显地促进他们的增高(磷酸化水平从2.0倍增到3.4倍, DNA结合活性从3.1倍增为5.1倍)。

In obese children, leptin concentration decreased during 4 mo of physical training and increased during a subsequent 4-mo period without physical training, fat mass was highly correlated with baseline leptin, and greater reductions in leptin during 4 mo of physical training were seen in children with higher pretraining leptin and in those whose total mass increased least.

在肥胖小孩中,4mol 周期体力运动使瘦素浓度降低,在接下来不运动的4-mo 周期中,瘦素水平提高。在那些体重增长最慢、运动前瘦素水平高的肥胖小孩中,4-mo 体力运动周期使其瘦素水平降低程度非常明显。第二篇翻译原文全文。pdf (43.99k)杂志,年,卷,期,页

Total protein content in serum maintained the highest level (P<0.10) and urea concentration in serum maintained the lowest level (P<0.10) similar to the condition in primiparous gilts which might mean higher protein efficiency to maternal body and fetus.

2经产妊娠母猪血清雌激素浓度在妊娠期维持相对高水平;孕激素妊娠前期维持相对高水平,后期维持相对低水平,其繁殖性能较好,与初产母猪的情况一致。

Results:Serum CYFRA21-1 level was significantly higher in the patients with protopathic breast cancer before operation(the positive rate was 21%)than the patients with benign breast diseases (serum CYFRA21-1 were all negative).

结果:乳腺良性疾病无1例阳性;乳腺癌术前阳性率仅21%,但两者血清 CYFRA21-1 水平有明显差异;47例乳腺癌患者手术前与术后 4周血清 CYFRA21-1 水平相比有显著差异;56例乳腺癌患者术后随访 8例转移复发者中 6例阳性,无转移复发者均阴性,转移复发者血清 CYFRA21-1 水平较无转移复发者明显增高,两者相比差异有极显著性。

Results:Serum CYFRA21-1 level was significantly higher in the patients with protopathic breast cancer before operation(the positive rate was 21%)than the patients with benign breast diseases (serum CYFRA21-1 were all negative).

结果ˇ乳ˇ良性疾病无1例阳性ˇ乳ˇ癌术前阳性率仅21%ˇ但两者血清 CYFRA21-1 水平有明ˇ差异ˇ47例乳ˇ癌患者手术前与术后 4周血清 CYFRA21-1 水平ˇ比有ˇ著差异ˇ56例乳ˇ癌患者术后随访 8例转移复发者中 6例阳性ˇ无转移复发者均阴性ˇ转移复发者血清 CYFRA21-1 水平较无转移复发者明ˇ增高ˇ两者ˇ比差异有极ˇ著性。

Objective To study the mechanism in which the personality, copying style influenced survival time by changing immunity function in the patients with gastric cancer Methods The Minnesota Multiphase Personality Inventory, coping style questionnaires and immunity function were measured in patients with gastric cancer on late stage, gastric cancer patients with longer survival time, and normal control Results Psychopathic deviate, social introversion subscale scores of MMPI in groupⅡ were significantly lower than that in the other two groups ( P 05) Statistical difference were found between groupⅠand groupⅡ in problem saving factor and help seeking factor of CSQ ( P 05) Natural killer cell level in groupⅡ was significantly higher than in groupⅠ( P 05) There was negative correlation between the NKC and depression, psychopathic deviate, paranoia, psychasthenia, schizophrenia subscale scores of MMPI, there was positive correlation between NKC and SP, coping type in patients with gastric cancer Conclusion The gastric cancer patients with longer survival time are more extroversive and have more mature coping styles Their NKC level is relatively higher The results may be advantageous to improve the prognosis of gastric cancer

作者中文名:王健;邹义壮;唐丽丽;李杰;张东;金山;刘娟摘要:目的研究胃癌患者的生存期与个性特征、应付方式等心理因素,以及免疫功能的关系。方法对胃癌晚期患者、胃癌较长生存期患者及正常健康人分别进行明尼苏达多相个性测验、应对方式问卷、免疫功能测试,并做相关分析。结果(1)MMPI:胃癌Ⅱ组人格障碍评分(42.0±10.5)及社会内向评分(42.2±11.6),低于其他两组[胃癌Ⅰ组为(49.3±11.2)分和(48.3±9.4)分,对照组为(48.6±10.9)分和(39.9±11.5)分;P均<0.05];(2)CSQ:解决问题和求助因子分,胃癌Ⅰ组[分别为(0.68±0.27)分和(0.42±0.18)分]均低于胃癌Ⅱ组[分别为(0.82±0.18)分和(0.65±0.21)分;P<0.05和P<0.01],胃癌Ⅱ组更多采取成熟的应对方式;(3)自然杀伤细胞:胃癌Ⅱ组水平(21.4±9.2)高于胃癌Ⅰ组[(14.2±8.8);P<0.05];而NK细胞水平与MMPI的抑郁(r=-0.35)、人格障碍(r=-0.39)、偏执(r=-0.29)、精神衰弱(r=-0.30)及精神分裂(r=-0.30)等量表呈负相关,与CSQ的解决问题因子(r=0.35)及应付方式类型(r=0.34)呈正相关。结论与胃癌Ⅰ组比较,胃癌Ⅱ组更为外向,负性情绪较少,更多采取成熟的应对方式,其NK细胞水平较高,对胃癌的预后产生了积极的影响。

Three nitrogen levels had increased dark respiration of Quercus mongalica seedlings under interaction of double CO2 concentration and elevated temperature.

氮素水平对最大光合速率影响也十分明显,不同处理条件下,高氮水平的最大光合速率明显高于低氮和不施氮水平

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And if officials on the take are not parroting the opinions of these companies, what can we suppose the money they receive is for?

如果受贿的官员不鹦鹉学舌般地复述这些公司的看法,那他们所接受的钱又能用于什么目的呢?

Love them, and love you too, Pitcher.

爱他们,也爱你,投手。

He was sent away to the island of Scyros,where he fell into sea from a cliff.

赶下了台。他被流放到塞库鲁斯岛。在那儿,他失足从悬崖上栽到了海里。