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氯醛麻醉

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This study demonstrates that a steady α-chloralose anesthesia can be achieved for fMRI study, which can be utilized in the study of drug, lesion or other brain experiments.

在本实验中,我们测试并达到了稳定的α-氯醛醣麻醉,而这个方法将可以应用在其他相关的实验上。

Experiments were carried out on rabbits; anesthetized with urethane and chloralose, paralyzed with flaxedil, and ventilated artificially.

实验在氯醛糖和氨基甲酸乙酯混合麻醉、三碘季铵酚麻痹、人工通气的家兔上进行。

Glomerular filtration rate and renal blood flow were determined in dogs anesthetized with chloralose or Na-pentobarbital.

三氯醛糖或戊巴比妥钠麻醉狗,应用肾脏对肌酐及对氨基马尿酸的清除率测定其肾小球滤过率及肾血流量。

Experments were carried out on male SD rats anesthetuzed with urethane (700 mg/kg) and chloralose (35 mg/kg).

雄性SD大鼠,用乌拉坦(700mg/kg)和氯醛糖(30mg/kg)腹腔麻醉。

Experiments were Performed on male SD rats anaesthetized with urethane(700 mg/kg) and chloralose(35 mg/kg).

上海医科大学生理学教研室。上海 200032摘要雄性Sprague-Dawey大鼠,用乌拉坦(70mg/kg)和氯醛糖(30mg/kg)腹腔麻醉。

Rats were anesthetized with urethane(700mg/kg) andα-chloralose(35mg/kg),and the trachea,femoral artery and extemal jugular vein were cannulated respectively.

2取成年SD大鼠(250~350g),乌拉坦(700mg/kg)和α-氯醛糖(35mg/kg)混合腹腔麻醉,行气管插管、颈外静脉插管、股动脉插管,游离一侧膈神经并穿线标记,缝合切口。

The effects of electroacupuncture on the pressor response and reversible myocardial dysfunction induced by application of bradykinin on the gallbladder were studied in cats anesthetized with α-chloralose. The cardiovascular responses evoked by application of BK included a pressor response, an increase of LVP and its dP/dtmax, tachycardia and a decrease of local wall motion of the left ventricle with a supplying branch of the left anterior descending coronary artery ligated beforehand.

在α-氯醛糖麻醉的猫上,结扎左心室冠状动脉前降支一小分支,对动物胆囊浆膜面予以缓激肽,可反射性地诱发血压、左心室内压升高、±dP/dtmax增大、心率加快,同时用超声单晶片声纳测微系统记录局部心壁运动,发现BK可以反射性地引起LAD小分支远端所支配的心肌运动功能减弱。

Objective To investigate the effects of pentobarbital sodium,chloraldurat and ethylcarbamate on hematology in female SD rats.

目的观察戊巴比妥钠、水合氯醛、氨基甲酸乙酯三种麻醉药物对雌性SD大鼠血液学指标的影响。

The central integrative part of the baroreflex receives afferent information not only from the sino-aortic baroreceptors, but also from various other sources. The present study was to investigate the effect of somatic nerve stimulation on baro-reflex. The exoeriment was performed in α-chloralose-urethane anesthetized rabbits. Intrasi- nusal pressure -mean arterial pressure res- ponse curves were constructed.

在自然状态下,各种传入冲动汇集中枢,很多传入冲动都可影响压力感受性反射,使压力感受性反射受到调制而发生重新调定·本实验旨在观察刺激躯体神经对压力感受性反射的重调定并分析其机制·实验在α-氯醛糖和氨基甲酸乙酯混合麻醉的家兔上进行,利用颈动脉窦灌流技术测量不同窦内压时体循环平均动脉压的水平,并画出窦内压-体循环平均动脉压反应曲线。

Methods: NG108-15 cells were cultured in vitro at 37℃in a humidified atmospherecontaining 5%CO_2. Aβ_(25~35) fragment was dissolved with deionized distilledwater and aged for 4 days at 37℃. The cells were exposured to 5μmol/LAβ_(25~35) for 24h to establish the cell model. Twelve rabbits were divided intotwo groups at random, and garaged with MWD or physiological saline controlrespectively for 7 days to collect two kinds of cerebrospinal fluid, theyare CSF from rabbits treated with MWD and CSF from rabbits treated withphysiological saline.

NG108-15细胞在37℃、体积分数为5%的CO_2培养箱中培养,Aβ_(25~35)溶解于双蒸水中,置于37℃培养箱中老化4d,使其寡聚,毒性增强,细胞被置于浓度为5μmol/L的Aβ_(25~35)中作用24h,建立起AD细胞模型。12只清洁级大耳白家兔购于华中科技大学同济医学院动物中心,将其随机分成两组,分别给与等量的加味温胆汤和生理盐水灌胃7d,末次给药后1h内用水合氯醛将给药组白兔麻醉,1.2ml/kg,无菌条件下用7号注射针头从枕骨大孔处垂直进针,抽取清亮含药脑脊液。

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