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The synthetic route starts from penicillin G, peroxyacetic acid(8.5%) as Oxidizing Agent to get penicillin G sulfoxide; esterifided with p-nitrobenzyl bromine to synthesize penicillin G sulfoxide ester; we synthesize 3-exomethylenecepham sulfoxide ester with phthalimide potassium and 4A molecular sieve as acid scavenger to open the ring, SnCl_4 as catalyzation to close the ring. The yield is over 60%.

本研究采用的合成路线为:以青霉素G钾盐为原料,选用工业过氧化氢制备的过氧乙酸(22.3%)稀释至8.5%为氧化剂,氧化得青霉素亚砜;采用对硝基溴苄为酯化试剂,制备青霉素亚砜酯;以NCP(N-氯代邻苯二甲酰亚胺)为开环试剂,酞酰亚胺钾和4A型分子筛为酸清除剂,顺利开环;再经无水SnCl_4催化闭环得3-环外亚甲基头孢亚砜酯,最终产率在60%以上。

Retina; ganglion cell layer; inner plexiform layer; chloride currents; glycine receptors; potassium conductance calcium-gated

视网膜;神经节细胞层;内网织层;氯电流;甘氨酸受体;钾电导钙-开启

Following the industrialization programme for gold nanomaterials, auric chloride acid, potassium gold cyanide, superfine and nano-scale gold powders and"liquid gold"can be produced systematically.

为贵金属纳米材料的产业化指明了方向。提出了以粗金为原料,在工业上生产氯金酸、氰化亚金钾、超细和纳米金粉、金水等含金深加工产品的产业化系统方案。

A large number of companies are producing high-quality reagent products, such as chloroform, ethanol, ammonium, potassium periodate, iodine, potassium iodide, stannous chloride, tin tablets octanol, hydrochloric acid and so on.

公司现生产大批优质试剂产品,如氯仿、无水乙醇、钼酸铵、高碘酸钾、碘、碘化钾、氯化亚锡、锡粒、正辛醇、盐酸等。

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This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。

There is no differences of cell proliferation vitality between labeled and unlabeled NSCs.

双标记神经干细胞的增殖、分化活力与未标记神经干细胞相比无改变。