氯酸

Following resolution, the following steps are performed: reduce the isomer to an alcohol, react the alcohol with triphenylmethyl chloride, ozonalyze the resulting reaction product, reduce the ozonalyzed product to yield a diol and react the diol with a methane sulfonyl compound to form-3-2-{(methylsulfonyloxy}ethoxy-4--1-butanol methane sulfonate.

拆分后，进行下一步：将异构体还原为醇，使醇与三苯基甲基氯反应，臭氧化所得反应产物，还原臭氧化产物以得到一种二醇并使所述二醇与甲烷磺酰基化合物反应以形成-3-2-{(甲基磺酰基氧}乙氧基-4--1-丁醇甲烷磺酸酯。

Hydroesterification of tert-butyl alcohol with ethanol catalyzed by transition metal triphenylphosphine complexes were investigated in room temperature ionic liquids as reaction medium at 100-140℃ and 3-6MPa of CO.

首次在超强酸氯铝酸离子液体中实现了饱和烷烃的羰化反应。发现2，2，4-三甲基戊烷可直接与CO反应，产物叔丁基异丁基酮，叔丁基异丁烯基酮和3，3，5-三甲基环己酮。

PBMC treated with inhibitor N-tosyl phenylalanine chlormethyl ketone, Astragalus can increase the activity of NF-κ B and the concentration of IL-8 in patients with PNS. it also increases the the activity of NF-κ B in normal children , but can ' t affected the concentration of IL-8 in normal children. ConclusionIn patients with PNS , the activity of NF-κ B was up-regulated and the level of IL-8 was significantly elevated.

结果肾病患儿 NF-κ B 活性及 IL-8含量增高，2者呈正相关； IL-1β刺激后，黄芪降低肾病患儿 NF-κ B 活性及 IL-8含量、降低正常儿童 NF-κ B 活性而不影响 IL-8含量；用对甲苯磺酰-L-苯丙氨酸氯甲基甲酮抑制后，黄芪可提高肾病患儿 NF-κ B 活性及 IL-8含量、提高正常儿童 NF-κ B 活性；而不影响 IL-8含量。

In the process, 2, 4-difluoroaniline is used to carry out ammoniated reaction. Then through a series of similar reactions, the important intermediate of temafloxacin, which is called 7-chloro-6-fluoro-1-(2, 4-difluorophenyl)-1, 4-dihydro-4-oxo-3-quinoline acid, is gained.

与环丙沙星和二氟沙星类似，用2，4-二氟苯胺进行胺化反应，再进行一系列类似的反应，制得合成替马沙星的关键中间体7-氯-6-氟-1-（2，4-二氟苯基）-1，4-二氢-4-氧代喹啉-3-羧酸。

It is also an intermediate chemical in the bacterial degradation of melamine and in the production of chlorinated bleaches and whitening agents.

然而，三聚氰酸和三氯三聚氰胺有着更加严重的潜在毒性，特别是可以导致肾脏损伤，发育毒性以及癌症。

Using the method of macerating, ZrOCl_2 loading on D418 was produced. Influence including time of macerating, pH, and temperature on the amount of load was studied. The proper conditions show that, room temperature is appropriate, the suitable pH is equal to 5, and time of macerating is 16 hours.

采用浸渍法，以ZrOCl_2·2H_2O和氨基膦酸树脂D418为原料，制备大孔螯合树脂D418负载的氯氧化锆，考察了浸渍时间、pH、温度对负载量的影响，得出适宜的操作条件为：室温，pH=5，浸渍时间为16小(来源：ABC347b34论文网www.abclunwen.com)时。

Kelch-like ECH-associated protein-1 (Keap1) normally sequesters Nrf2 in the cytoplasm in association with the actin cytoskeleton, but upon oxidation of cysteine residues Nrf2 dissociates from Keap1, translocates to the nucleus and binds to ARE sequences leading to transcriptional activation of antioxidant and phase II detoxifying genes.

在正常情况下，Kelch样环氧氯丙烷相关蛋白-1 (Kelch-like ECH-associated protein-1， Keap1)可将Nrf2与肌动蛋白细胞骨架一起收集在细胞质内，但是在半胱氨酸残基发生氧化的情况下，Nrf2和Keap1脱离，进入细胞核并与ARE结合，从而激活多种抗氧化基因和II相解毒基因的转录。

Kelch-like ECH-associated protein-1 (Keap1) normally sequesters Nrf2 in the cytoplasm in association with the actin cytoskeleton, but upon oxidation of cysteine residues Nrf2 dissociates from Keap1, translocates to the nucleus and binds to ARE sequences leading to transcriptional activation of antioxidant and phase Ⅱ detoxifying genes.

在正常情况下，Kelch样环氧氯丙烷相关蛋白－1(Kelch-like ECH-associated protein-1， Keap1)与Nrf2耦联，并与肌动蛋白细胞骨架结合被锚定于胞浆，但是在半胱氨酸残基发生氧化的情况下，Nrf2和Keap1解耦联，进入细胞核并与ARE结合，从而激活多种抗氧化基因和Ⅱ相解毒酶基因的转录。

The method could be used for detection of the related substances in Diclofenac Sodium Suppositories.

该法可用于双氯芬酸钠中有关物质的检查。

The accuracy and precision of the result accorded with the demand of titrating analysis.

自制微型滴定装置具有较好的操作性能和精密度，符合滴定分析法的要求，可用于测定马来酸氯苯那敏的含量。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。