氯胺酮

Ketamine, a derivative of cyclohexanone, structurally like the phencyclidine, is one anesthesia drug of short duration.

氯胺酮，又名开他敏，是一种在结构上与苯环己哌啶有关的环己酮衍生物。

Propofol pretreatment can significantly inhibit ketamine-induced HSP 70 mRNA and protein expression in the posterior cingulated cortex. It may be one of the mechanisms of inhibition of ketamine-induced psychotomimetic effect and neuronal damage by propofol.

结论异丙酚可抑制氯胺酮诱导的HSP 70 mRNA与HSP 70蛋白在大鼠后扣带回皮质区的表达，这可能是其预防或减轻氯胺酮所致精神症状和神经损害的机制之一。

Results The levels of HSP 70 mRNA and HSP 70 protein expression were significantly different among the 5 groups. Ketamine induced marked HSP 70 mRNA and HSP 70 protein expression in the posterior cingulated cortex. Propofol itself did not induce HSP 70 gene expression in this brain region. Propofol significantly inhibited ketamine-induced HSP 70 mRNA and HSP 70 protein expression in the posterior cingulate cortex in a dose-dependent manner.

结果氯胺酮可明显诱导HSP70 mRNA与HSP70蛋白在大鼠后扣带回皮质区的表达；异丙酚自身不能诱导HSP70基因的表达；预先给予异丙酚可显著抑制氯胺酮诱导的HSP70 mRNA和HSP70蛋白在这一区域的表达，且抑制效应呈剂量依赖性。

Convulsion was induced by intravenous strychnine 0.25 mgkg^(-1. Normal saline and the different dose of ketamine were intravenously administered, respectively. Mortality and duration of tonic state were observed. The EEG activity was monitored continuatively.

耳缘静脉注射士的宁0.25mgkg^(-1)制作惊厥模型，分别静脉注射氯胺酮或相应剂量的生理盐水，观察氯胺酮对家兔的死亡率和强直持续期的影响。

But Ketamine involves the main excitory neurotransmitter in the brain called glutamate. Ketamine functions by blocking glutamate's action on the N-methyl-D-aspartic acid receptor.

但是氯胺酮包括主要的大脑兴奋性神经递质谷氨酸，氯胺酮通过抑制谷氨酸对N－甲基－D－天冬氨酸受体起作用。

Methods Forty-five patients with hysteromyoma undergone hysteromyomectomy were randomly assigned to three groups (n=15,each group): group Ⅰ, control group without pre-emptive analgesia; group Ⅱ, the patients were administrated with 0.2 mg·kg-1 ketamine intravenously 30 min before operation; group Ⅲ, 30 mg ketamine was administrated into epidural analgesia 30 min before operation.

45例子宫肌瘤患者均于硬膜外麻醉行全子宫切除术，随机分为3组，即Ⅰ组：对照组，术前不施行超前镇痛；Ⅱ组：切皮前30 min静脉注入氯胺酮0.2 mg·kg-1；Ⅲ组：切皮前30 min将氯胺酮30 mg加入实验剂量(2%利多卡因4或5 mL)中注入硬膜外腔。3组术后均连接Graseby9300镇痛泵行患者自控硬腺外镇痛，镇痛药物为0.2%罗哌卡因加50 mg·L-1吗啡。

After ketamine and compound chlorderazin were intramuscularly injected according to 25 mg/kg. constrast medium of Omnipaque 300 mgI/ml （dosage 2.6 ml/kg/weight） was injected into the postauricular central vein.

按25 mg/kg氯胺酮加复方氯丙嗪针肌注麻醉后，经耳后中央静脉穿刺注射非离子型对比剂（Omnipaque 300 mgI/ml）。

To investigate the effect of ketamine on hepatic mitochondria in septic mice. Cecal ligation and puncture were used to make a sepsis model.

目的 探讨氯胺酮对脓毒症大鼠肝线粒体能量代谢的影响以及氯胺酮对脓毒症肝损伤的保护机制。

Patients with shivering grade 3–4 were allocated to receiveeither meperidine 25 mg, ketamine 0.5 mg/kg, or ketamine 0.75mg/kg IV.

寒战评分3－4级的病人分成3组，分别静脉注入哌替啶25mg 、氯胺酮0.5mg/kg 或氯胺酮0.75mg/kg 。

Patients with shivering grade 3–4 were allocated to receiveeither meperidine 25 mg, ketamine 0.5 mg/kg, or ketamine 0.75mg/kg IV.

寒战评分3－4级的病人分成3组，分别静脉注入呱替啶25mg 、氯胺酮0.5mg/kg 或氯胺酮0.75mg/kg 。

I am accused of being overreligious," she said in her quiet, frank manner,"but that does not prevent me thinking the children very cruel who obstinately commit such suicide.""

客人们在卡罗利娜·埃凯家里，举止就文雅一些，因为卡罗利娜的母亲治家很严厉。

Designed by French fashion house Herm è s, this elegant uniform was manufactured in our home, Hong Kong, and was the first without a hat.

由著名品牌 Herm è s 设计，这件高贵的制服是香港本土制造，是我们第一套不配帽子的制服。