氯氨铂

The most commonly used drugs Bleomycin, mitomycin C, Adriamycin, 5 - 5-fluorouracil (5 - Fu), methotrexate, cyclohexyl - nitrosourea, imipramine hydrazone, Vindesine, etoposide (VP-16), chlorine and ammonia-platinum, a single chemotherapy drug remission rate in the 15% to 20% remission for 1 to 4 months.

最常用的药物有博来霉素、丝裂霉素C、阿霉素、5-氟尿嘧啶（5-Fu）、甲氨喋呤、环己亚硝脲、丙咪腙、长春花碱酰胺、鬼臼乙叉甙（VP-16），以及顺氯氨铂，单一药物化疗的缓解率在15％～20％，缓解期为1～4个月。

INTERVENTIONS: In experimental group, the emetic, cisplatin, was injected abdominally 10 mg/kg. In the control, the physiological saline of same dose was injected. Afterwards, the activity changes in rats were observed at room temperature, quiet and light-avoided environment. Six hours later, the brain tissue was collected for frozen continuous sectioning. Immunohistochemical staining method was used to observe the distribution of Fos positive neurons in brainstem and forebrain nuclei and to count positive cell.

干预：实验组腹腔注射催吐剂顺氯氨铂10 mg/kg，对照组注射等剂量的生理盐水后，于室温、安静、避光环境下观察大鼠的行为学变化。6 h后取大鼠脑组织，进行冷冻连续切片，用免疫组织化学染色方法观察大鼠脑干和前脑核团的Fos阳性神经元的分布，并进行阳性细胞记数。

Our company supply raw materials and related intermediates as follows: Second dibutyryl cAMP calcium, voriconazole, terbinafine, vecuronium amines, cAMP, thiamphenicol, a chlorophenol hydrochloride esters, card network sodium phosphate tilmicosin, foscarnet, lornoxicam, Tilmicosin, Cephalosporium aspirin acid, ceftiofur hydrochloride, ceftiofur sodium, Ozagrel, ondansetron hydrochloride ketones, hydroxyurea, ticarcillin sodium, telmisartan, esmolol hydrochloride, hydrochloric acid Daguan Nikkomycin, adefovir dipivoxil, buflomedil hydrochloride, granisetron hydrochloride, warfarin sodium,-methyl gabexate acid, nicergoline, pantoprazole sodium,·, tegafur, cefepime hydrochloride, vecuronium bromide, hydrochloric acid meclofenoxate, sertraline hydrochloride, Cefonicid amine salt, aztreonam, ticarcillin, cefdinir, cefodizime sodium, sodium ferulate, colloidal pectin secretion, 2,3 - cyclopentene and pyridine, Piperacillin acid, cefetamet US-acid, hydrochloride Cefmenoxime ,3-TZ, 2 - deoxy-D-glucose, two-amidine urea benzene, sodium Cefonicid, Cefonicid intermediates, ester Cefamandole sodium, Cefalotin acid, intermediates cefpirome, cefepime sulphate, cefepime intermediate nucleus of cefepime, cefpirome nucleus, Cefamandole sodium, ceftriaxone new active ester, oxaliplatin, cyclophosphamide vary gland amines, polyene match him.

我公司供应的原料药及相关中间体为：二丁酰环磷腺苷钙、伏立康唑、盐酸特比萘芬、维库溴胺、环磷腺苷、甲砜霉素、盐酸甲氯酚酯、卡络磺钠、磷酸替米考星、膦甲酸钠、氯诺昔康、替米考星、头孢匹胺酸、头孢噻呋盐酸盐、头孢噻呋钠、奥扎格雷、盐酸恩丹西酮、羟基脲、替卡西林钠、替米沙坦、盐酸艾司洛尔、盐酸大观霉素、阿德福韦酯、盐酸丁咯地尔、盐酸格拉司琼、华法林钠、甲磺酸加贝酯、尼麦角林、泮托拉唑钠、普拉洛芬、替加氟、盐酸头孢吡肟、维库溴铵、盐酸甲氯芬酯、盐酸舍曲林、头孢尼西胺盐、氨曲南、替卡西林、头孢地尼、头孢地嗪钠、阿魏酸钠、胶体果胶泌、2，3-环戊烯并吡啶、哌拉西林酸、头孢他美酸、头孢甲肟盐酸盐、3-TZ、2-脱氧-D-葡萄糖、双脒苯脲、头孢尼西钠、头孢尼西中间体、头孢孟多酯钠、头孢噻吩酸、头孢匹罗中间体、头孢吡肟硫酸盐、头孢吡肟中间体、头孢吡肟母核、头孢匹罗母核、头孢孟多钠、头孢曲松新型活性酯、奥沙利铂、异环磷腺胺，多烯他赛。

Experimental results showed that the relative average error of the proposed method, the hydrazine hydrate gravimetry and the ammonium chloroplatinate gravimetry is -0.14%~+0.13%,-0.21%~+0.21% and -0.13%~+0.14%, respectively, and the relative standard deviation of three methods is 0.05%~0.08%, 0.11%~0.14% and 0.08%~0.09%, respectively, for Pt content from 37% to 65%. Therefore, the accuracy and precision of the proposed method are almost the same with hydrazine hydrate gravimetry, and are a little better than ammonium chloroplatinate gravimetry. But it is rapid, economic, secure, easy to operate and environmental friendly.

结果表明：测定37%~65%的Pt含量，本法、氯铂酸氨重量法、水合肼还原重量法的相对平均误差分别为-0.14%~+0.13%、-0.21%~+0.21%、-0.13%~+0.14%，相对标准偏差分别为0.05%~0.08%、0.11%~0.14%、0.08%~0.09%，故本法的准确度和精密度与水合肼还原重量法的基本一致，较氯铂酸氨重量法的略好；但本法消解快速、节能、安全，操作简便，对环境污染程度小，适宜推广运用。

We devote in the research, development, production and marketing of precious metal compound and related products with reliable quality, such as; potassium gold noncyanide, Rhodium sulphate, potassium tetrabroaurate, Chloroplatinic acid, gold chloride, Ammonium chloropalladate, Ammonium tetrachloropalladate, recycled and refined precious metals etc.

公司主要从事贵金属材料相关产品的研究、开发、生产和销售，主要产品有无氰金盐和其他贵金属化合物，包括：硫酸铑、溴金酸钾、氯铂酸、三氯化金、二氯化二氨络钯、二氯化四氨络钯等，并提供贵金属资源二次回收服务。

Cis dichloroamine (4 amino 2,2,6,6 tetramethylpiperidine 1 oxyl) platinum(abbreviated to HJ5) is a novel platinum anticancer compound which has prospects for research and application.

顺 二氯一氨(4 氨基 2 ，2 ，6 ，6 四甲基哌啶 1 氧自由基)合铂(简称HJ5 )是一种有研究与应用前景的新型铂抗癌配合物。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐