氯噻

Pentanediol dithiophene ester was synthesized by means of alcoholysis reaction using 2,4-Pentanediol and Aroly chloride as raw materials, and 1H NMR spectrum was characterized and it can not be explained.

以2，4-戊二醇和芳酰氯为原料，通过醇解反应合成了一种新的内给电子体化合物二(2-噻吩甲酸)-2，4-戊二醇酯，表征其1H-NMR谱，发现化学位移在2附近出现了三组亚甲基峰，无法解释。

Photoinduced reactions of 1 with 15, 16 and 19 gave the corresponding annulation products 21 (58%), 30 (71%) and 35 (87%) directly in one pot sequential reactions.

二氯香豆素（1）可分别与2-和3-苯基苯并呋喃以及2-甲基-4-苯基噻唑在光照条件下经一锅内的连续反应直接合成增环产物21（58％），30（71％）和35（87％）。

240 patients with high p latelet aggregating activity were randomized equally into following groups: clop idogrel group and ticlopidine group.

将筛选具有血小板高聚集性的240例患者随机分入氯吡格雷组与噻氯匹定组，分别服用CPG 50mg和TCP 250mg，或TCP片250mg和C PG安慰片50mg，总疗程4周。

Result: Platelet aggregation rate of pretreatment and 8 weeks after treatment had significant difference, but hemostatic functions were similar. The incidence of cardiac event of two groups had no significant difference. The side effect of Clopidogrel and Ticlopidine had significant difference with granulocytopenia (3.4% vs. 0), gastrointestinal tract response (11.2% vs. 6.3%) and exanthem (9.0% vs. 3.2%) respectively, which need no drug withdrawal.

结果：治疗8周后的血小板聚集率与治疗前相比，差异具有显著性，而止血和血栓功能相似；治疗后两组心脏事件的发生率相似；噻氯匹定与氯吡格雷的副作用中性粒细胞减少（3.4％比0）、胃肠道反应（11.2％比6.3％）、皮疹（9.0％比3.2％），两组差异具有显著性，两组均无需要停药病。

Objective To investigate the safety and efficiency of ticlopidine and warfarin on intracardiac mural thrombus.

目的观察噻氯吡啶与华法林在治疗心腔内附壁血栓的疗效及安全性。

Objective: To assess the clinical effect and security of Astragalus Membranaceus Injection in leucopenia patients induced by ticlopidine.

目的 评价黄芪注射液治疗噻氯匹定引起的白细胞减少症的临床疗效和安全性。

Leucopenia patients induced by ticlopidine can be treated with AMI effectively without side effect .

黄芪注射液治疗噻氯匹定引起的白细胞减少症有显著疗效，且无明显的副反应。

The preparation of phenyl chloroformate and chloroformic acid l,3-thiazole-5-ylmethyl ester with biscarbonate was studied.

然后研究了双碳酸酯在合成氯甲酸苯酯和氯甲酸-1，3-噻唑基-5-甲酯的应用。

The preparation of phenyl chloroformate and chloroformic acidl,3-thiazole-5-ylmethyl ester with biscarbonate was studied.

然后研究了双碳酸酯在合成氯甲酸苯酯和氯甲酸-1，3-噻唑基-5-甲酯的应用。

In order to improve the catalytic performances of the chloroaluminate, some organic chemicals with strong electron-donating capacity,such as benzene,alkylbenzene,thioalcohol and thiophene,were introduced into the ionic liquids to modify the ionic liquids.

为改善氯铝酸离子液体的催化性能，向氯铝酸离子液体中引入微量具有供电子能力的苯，烷基苯，硫醇，噻吩等助剂，对离子液体进行改性。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。