氯乙酸

The optimum reaction conditions are as follows: diphenylmethanethiol : methyl chloroacetate is 1:1.5, and the reaction carried out at 100℃ for 4 h, 2- acetamide can be carried out in the room temperature for 20 h, the yield of 2- acetamide was 76%, hydrogen dioxide: 2- acetamide is 1:1, and the reaction carried out at 60℃ for 3 h, the yield of modafinil was 79%, the total yield of reaction can be reached 48%.

研究表明，采用氯乙酸甲酯作为醚化试剂，反应时间4h，反应温度100℃，二苯甲硫醇：氯乙酸甲酯=1：1.5，室温下氨解反应20h，二苯甲硫乙酰胺收率76%；采用过氧化氢作为氧化试剂，反应时间3h，反应温度60℃，过氧化氢：二苯甲硫乙酰胺=1：l，莫达非尼收率79%，反应总收率可达48%。

Chapter two 4-Hydroxybenzoic acid is connected with PEG6000 through defoliant DCC at rooom temperature, then the product is refluxed with chloroacetic acid in acetone to afford PEG-bound phenyloxyacetic acid, which is reacted with thionyl chloride, ammonium thiocyanate and arylamines in turn to give PEG-bound disubstituded thioureas. After the cleavage with sodium methoxide in methanol, the eleven disubstituted thioureas are obtained.

第二章 利用PEG6000作载体，通过脱水剂DCC在室温下将对羟基苯甲酸以酯键连接在PEG6000上，再与氯乙酸在较温和的条件下生成PEG6000支载的芳氧乙酸，然后，依次与亚硫酰氯、硫氰酸铵、芳胺反应，生成PEG6000支载的硫脲，最后用甲醇钠的甲醇溶液切割PEG，得到了十一种1，3-二取代硫脲。

We supply high quality MCA to customers domestically and abroad. On request of US-based Cpkelco Company, we are now increasing our production capability to deliver MCA water impregnant to Cpkelco Taixing plant by pipeline.

在为国内外客户提供优质固体氯乙酸的基础上，应美国斯比凯可公司的需求，泰兴工厂还进行了扩容，通过管道运输方式向其泰兴工厂供应氯乙酸水溶液。

Esterification of terpineol with oxalic acid, chloroacetic acid and trichloroacetic acid by solid superacid MoO3/TiO2 was studied.

研究了MoO3/TiO2固体超强酸催化剂催化松节油与草酸，氯乙酸，三氯乙酸反应的规律。

N,N'-ethylenediamine diacetic acid was prepared by condensation of ethylenediamine, formaldehyde and potassium cyanide. Then 2-oxo-1-piperazine acetic acid was prepared from N,N'-ethylenediamine diacetic acid. In addition, 2-oxo-1, 4-piperazine diacetic acid(3-KP) was prepared from 2-oxo-1-piperazine acetic acid with chloroacetic acid.

本文用乙二胺、甲醛和氰化钾合成了N，N′—乙二胺二乙酸，然后由N，N′—乙二胺二乙酸合成了2—氧—1—哌嗪乙酸，再由2—氧—1—哌嗪乙酸和氯乙酸合成了2—氧—1，4—哌嗪二乙酸(3-KP)。

DCA, or dichloroacetic acid, is an analogue of acetic acid in which chlorine atoms replace two of the three hydrogen atoms on the methyl group.

DCA也叫二氯乙酸或二氯醋酸，是一种类似乙酸的化合物，但乙基团上有两个氢原子被氯原子所取代。

A series of novel polyethylene glycol derivates was synthesized by esterification of chloroacetic acid with polyethylene glycol. Because of the good reactive activity of α-chlorin in the esters it can react with 5-fluorouracil, thus the conjugate can be obtained .

采用氯乙酸与不同分子量的聚乙二醇进行酯化反应得到氯乙酸聚乙二醇酯，由于酯中的α-氯具有良好的反应活性，将它再与抗癌药物5-氟尿嘧啶结合制备了不同分子量的高分子前药。

And the application of glycollic acid in the fields of chemical cleaning, auxiliaries and materials were introduced in detail.

概述了羟基乙酸几种主要工业合成方法的工艺条件及存在的主要问题，即氯乙酸水解法、氰化法、甲醛羰基化法和一氯乙酸钾水解法。

A brief account of technique conditions of several main technique routes for synthesizing glycollic acid and existing main problems in it are given.

概述了羟基乙酸几种主要工业合成方法的工艺条件及存在的主要问题，即氯乙酸水解法、氰化法、甲醛羰基化法和一氯乙酸钾水解法。

The effect factors on glycolic acid ratio were studied(reaction temperature,reaction time,and the ratio of catalyst to choloroacetic acid).

以氯乙酸和氢氧化钠为主要原料，碘化钠为催化剂碱性水解法合成羟基乙酸，并采用单因素法对影响因素进行了研究，得到最优化条件：反应温度90℃，反应时间8 h，催化剂NaI用量为氯乙酸质量的0.8%。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。