氨血

Surveillance: routine follow-up in a metabolic clinic; monitoring for hyperammonemia and secondary deficiency of essential amino acids; monitoring older individuals for signs of impending hyperammonia (i.e., mood changes, headache, lethargy, nausea, vomiting, refusal to feed, ankle clonus) and elevated plasma glutamine concentration.

监控：在代谢诊所里日常的随访；监测高血氨和必须氨基酸的并发性缺乏；监测较年长患者的高血氨前驱期症状（例如情绪改变、头痛、嗜眠、恶心、呕吐、拒绝进食、脚踝阵挛）和升高的血浆谷氨酰胺。

Laboratory findings show severe metabolic acidosis, ketosis and ketonuria, hyperammonemia, hyperglycinemia, thrombocytopenia, and neutropenia.

实验室化验显示严重的代谢酸中毒、酮病及酮尿、血氨过多、血内甘氨酸过多、血小板减少和中性粒细胞减少。

in order to probe into whether glycine supplementation plays an adjusting role in sports performance and immune functions, the authors divided 30 mice randomly into an exhaustive exercising group (e1), glycine supplemented exhaustive exercising group (e2) and a normal resting control group, with 10 mice in each group, supplemented glycine to mice in group e2 and physiological saline to mice in the other two groups, let mice in groups e1 and e2 do an exhaustive swimming exercise 4 weeks later, applied the trace ch50 hemolysis method to analyze supplement activity, applied the mtt method to perform a quantitative analysis on the lymphopoiesis ability of spleen, and thus revealed the following findings: compared with mice in group e1, the time taken by mice in group e2 to swim to an exhausted state is significantly longer (p.05); total supplement activity in blood serum of mice in group e1 is significantly lower than the same of mice in group s (p＜0.01), and total supplement activity in blood serum of mice in group e2 is significantly higher than the same of mice in group e1 (p.01), but still significantly lower than the same of mice in group s (p.05); as observed from the test of the lymphopoiesis ability of spleen, the lymphopoiesis ability of spleen of mice in group e1 is significantly lower than the same of mice in group s, and the lymphopoiesis ability of spleen of mice in group e2 is significantly higher than the same of mice in group e1, but still significantly lower than the same of mice in group s.

四型肽精氨酸脱氨酶在类风湿性关节炎。。。以马来酸酐与氨水为原料热缩聚法合成。。。摘要：为探讨甘氨酸补充对运动能力及免疫功能是否具有调节作用，将30只小鼠随机分成力竭游泳运动组(e1)、甘氨酸补充后力竭游泳组(e2)和静息正常对照组，每组10只。在e2组补充甘氨酸，其余两组给予生理盐水，处理4周后，e1组和e2组均做力竭性游泳运动。采用微量ch50溶血法分析补体活性，采用mtt法定量分析脾脏淋巴细胞增殖能力。结果显示，与e1组比较，e2组游泳至力竭的时间显著延长(p＜0.01)。e1组血清总补体活性显著低于s组(p＜0.01)，e2组显著高于e1组(p.01)，但仍显著低于s组(p.05)。在脾脏淋巴细胞增殖试验中观察到，e1组显著低于s组，e2组显著高于e1组但仍显著低于s组。

Methods: Twenty-four Kkay mice were divided into three groups(n=8):diabetes group,methionine-diet group,folic acid and vitamin B12 treatment group. C57Bl/6 mice were used as controls(C57). Four months later,the mice were sacrificed and their serum levels of Hcy,folic acid and vitamin B12 were measured by fluorescence polarization immunoassay. Pathological changes in kidneys were examined with the periodic acid schiff method with periodic acid-silver methenamine staining under electron microscope. Expression of MMP-9 protein or mRNA was detected by RT-PCR with immunohistochemical staining. Results: Different morphological changes of DN were found in Kkay mice.

Kkay糖尿病鼠随机分3组：糖尿病组、高蛋氨酸组和叶酸、维生素B12组，C57BL/6鼠为对照(C57)，以相应饲料喂养4个月后取材，测定血糖、血同型半胱氨酸、叶酸和维生素B12，以PAS、六氨银染色法光镜下及超微电镜观察各组DN病变，比较各组肾小球硬化指数；以免疫组化和半定量图像分析肾小球MMP-9蛋白表达，并以RT-PCR检测肾脏MMP-9 mRNA水平。

Results\ The levels of some essential amino acids like valine,leucine and histidine were significantly lower than those of normal controls.

结果 血透患者在透析前的必需氨基酸除苯丙氨酸外均较正常对照组降低，其中以缬氨酸、亮氨酸和组氨酸下降为显著；非必需氨基酸中精氨酸、甘氨酸和鸟氨酸明显升高；酪氨酸/苯丙氨酸和丝氨酸/甘氨酸的比值较对照组明显降低。

Laboratory evaluation consists of hematocrit (hemoconcentration suggests preeclampsia), platelet count, protein excretion, serum creatinine, serum uric acid, serum alanine and aspartate aminotransferase concentrations, and lactic acid dehydrogenase concentration.

实验室评估包括红细胞压积，血小板计数，蛋白排泄，血肌酐，血尿酸，血清丙氨酸氨基转化酶和天门冬氨酸氨基转化酶，和乳酸脱氢酶浓度

The patients with methylmalonic acidemia and homocystinuria should be mainly treated with vitamin B12, betaine and L-carnitine, while the patients with isolated methymalonic acidemia should be treated with protein restriction, the special milk formula without isoleucine, valine, methionine, and threonine, and be given L-carnitine.

对伴有同型半胱氨酸血症患儿，治疗以维生素B12、甜菜碱和左旋肉碱为主；对不伴有同型半胱氨酸血症患儿以限制天然蛋白质摄入，给予去除异亮氨酸、缬氨酸、甲硫氨酸和苏氨酸的特殊奶粉及左旋肉碱治疗为主。

Diet-induced hyperhomocysteinemia can exacerbate intimal hyperplasia after denuding injury, making hyperhomocysteinemia a likely risk factor for postangioplasty restenosis.

高同型半胱氨酸血症能使球囊损伤后颈动脉新内膜增生恶化，预示高同型半胱氨酸血症可能是血管成形术后再狭窄的一个独立危险因素。

The drug is also approved for use as maintenance therapy for chronic hyperammonemia that results from NAGS deficiency.

同时还批准该药物作为 NAGS 缺乏所致慢性高氨血症的维持治疗药物。

The remaining 4 mL was used for detecting the level of serum folacin and vitamine B12 with bioradiation assay.

住院第1天空腹抽取静脉血6 mL，取2 mL测定空腹血浆总同型半胱氨酸水平利用高效液相色谱法，空腹采血后即刻口服蛋氨酸0.1 g/kg，4 h后再次取血检测血浆总同型半胱氨酸水平；取其余4 mL空腹抽取的静脉血检测血清叶酸、维生素B12采用化学发光法。

I didn't watch TV last night, because it .

昨晚我没有看电视，因为电视机坏了。

Since this year, in a lot of villages of Beijing, TV of elevator liquid crystal was removed.

今年以来，在北京的很多小区里，电梯液晶电视被撤了下来。