氨脂

The total syntheses of sphingosine , ceramide and glycosphingolipid were reviewed with emphasis on the recent progresses.

综述了神经鞘氨醇、神经酰胺及鞘糖脂全合成研究的基本概况，重点评述了其最近的研究进展情

FTY720, a Synthetic Sphingosine 1 Phosphate Analogue, Inhibits Deelopment of Atherosclerosis in Low-Density Lipoprotein Receptor–Deficient Mice

FTY720，一种合成的鞘氨醇1磷酸盐类似物，可抑制低密度脂蛋白受体缺陷鼠动脉粥样硬化的发展

Meanwhile, their physiological activities such as enzymatic inhibition (5lipoxygenase and tyrosinase) and anti-inflammatory activities were studied.

并对它们进行了生理活性研究，如对5-脂氧合酶、酪氨酸酶的抑制以及抗炎活性研究。

Aqua, Oryza sativa, Stearic Acid, Glycol Stearate, Propylene Glycol, Sesamum Indicum Oil, Sodium Cocoamphoacetate, Prunus Amygdalus Dulcis Oil, Glyceryl Stearate SE, Laneth-15, Benzyl Alcohol, Bertholletia Excelsa Nut Oil, Panthenol, Parfum, Tocopheryl Acetate, Sodium Chloride, Phenoxyethanol, Creatine, Sodium Hydroxide, Methylparaben, Retinyl Palmitate, Butylparaben, Ethylparaben, Hydrolyzed Lepidium Meyenii Root, Isobutylparaben, Propylparaben, 1,2-Hexanediol, Capryloyl Glycine, Caprylyl Glycol, Citric Acid.

成分秘鲁人参精华及肌氨酸给予肌肤活力，紧致光滑肌肤大米精华温和的去除表面死皮，让肌肤看起来健康有活力有机芝麻油是极好的保湿成分，能很好的软化肌肤，特别是敏感皮肤。天然类脂作用于脂肪酸，修复并帮助储存肌肤能量，为肌肤铸造天然的防护层，防止水分及营养流失。

Methods 60 female mice were randomly divided into 4 groups (n=15):Mice in normal control group received subcutaneous injection of normal saline and mice in the other 3 groups received cervicodorsal injection of D-galactose[1000 mg/(kg1·d)] for 42 d to establish subacute aging model.

60只雌性昆明种小鼠，随机分为4组(n=15)：正常对照组皮下注射生理盐水；其余3组每日颈背部皮下注射 D-半乳糖[1000 mg/] 造成小鼠衰老模型，同时各组分别灌胃生理盐水、枸杞多糖[200 mg/]、丹参酮[1 500 mg/]。42 d后，测定小鼠背部皮肤组织匀浆中超氧化物歧化酶活力、过氧化脂质代谢产物丙二醛含量和皮肤羟脯氨酸含量。

objective to compare the anti-aging effects of lycium barbarum polysaccharides and tanshinone on the skin of d-galactose-induced mice aging model.methods 60 female mice were randomly divided into 4 groups (n=15):mice in normal control group received subcutaneous injection of normal saline and mice in the other 3 groups received cervicodorsal injection of d-galactose［1000 mg/(kg1·d)］ for 42 d to establish subacute aging model.the experimental groups included agingmodel group,lycium barbarum polysaccharides ［200 mg／group,tanshinone ［1 500 mg／］ group.forty two days later,the dorsal skin samples were collected to determine sod activities、mda and hydroxyproline contents.

目的 比较枸杞多糖与丹参酮对衰老小鼠皮肤的抗衰老作用。方法 60只雌性昆明种小鼠，随机分为4组(n=15)：正常对照组皮下注射生理盐水；其余3组每日颈背部皮下注射 d-半乳糖［1000 mg/］造成小鼠衰老模型，同时各组分别灌胃生理盐水、枸杞多糖［200 mg/］、丹参酮［1 500 mg/］。42 d后，测定小鼠背部皮肤组织匀浆中超氧化物歧化酶活力、过氧化脂质代谢产物丙二醛含量和皮肤羟脯氨酸含量。

objective to compare the anti-aging effects of lycium barbarum polysaccharides and tanshinone on the skin of d-galactose-induced mice aging model.methods 60 female mice were randomly divided into 4 groups (n=15):mice in normal control group received subcutaneous injection of normal saline and mice in the other 3 groups received cervicodorsal injection of d-galactose［1000 mg/(kg1·d)］ for 42 d to establish subacute aging model.the experimental groups included agingmodel group,lycium barbarum polysaccharides ［200 mg／group,tanshinone ［1 500 mg／］ group.forty two days later,the dorsal skin samples were collected to determine sod activities、mda and hydroxyproline contents.

60只雌性昆明种小鼠，随机分为4组(n=15)：正常对照组皮下注射生理盐水；其余3组每日颈背部皮下注射 d-半乳糖［1000 mg/］造成小鼠衰老模型，同时各组分别灌胃生理盐水、枸杞多糖［200 mg/］、丹参酮［1 500 mg/］。42 d后，测定小鼠背部皮肤组织匀浆中超氧化物歧化酶活力、过氧化脂质代谢产物丙二醛含量和皮肤羟脯氨酸含量。

Methods AMMC were incubated with different concentrations of aqueous extracts of Cuscuta chinensis Lain and 8-MOP, then activity of tyrosinase, melanin content and rate of proliferation of AMMC were tested respectively.

方法以8-甲氧补骨脂素（8-MOP）作为阳性对照，选择系列浓度的中药菟丝子水提取物和8-MOP作用于体外培养的AMMC，然后测定酪氨酸酶活性、黑素含量和细胞增殖率的变化。

Guanxinkang may decrease the the levelof homocysteic acid in the blood, improve the metabolic disturbance of lipoids,alleviate the hyperplasy of endangium, antagonize various factor cause AS and hasevident role in anti-AS.

2中药冠心康复方能明显降低血浆中同型半胱氨酸含量，改善脂质代谢紊乱，减轻内膜增生程度，拮抗上述各种致AS因素，具有明显的抗AS作用。

Now we don't know how aminoglycoside antibiotics damages hair cells, but there are some theories about it, such as:(1)AmAn affects the transformation among phosphoinositoln, inositol- 3-phophate and glycerine-2-acyl, also, it can cause the change of Ca2+ concentration in endocellular.

氨基糖甙类抗生素(aminoglycoside antibiotics， AmAn)损伤毛细胞的机制尚不清楚，但有以下几种学说：(1)影响了磷酸肌醇、三磷酸肌醇、二脂酰甘油间转化从而导致细胞内钙离子浓度的变化；(2)抑制G蛋白和鸟氨酸脱羧酶活性；(3)氨基糖甙类抗生素能引起内耳毛细胞的凋亡。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。