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These data primarily demonstrate possible mechanism for PFDoA induced hepatic steatosis: perturbation of fatty acid uptake, lipogenesis and fatty acid oxidation.

PFDoA对大鼠的毒性作用呈现一定的剂量依赖关系,主要表现在脂蛋白、不饱和脂肪酸的剂量依赖性下降和葡萄糖、柠檬酸、甲酸、异亮氨酸、缬氨酸的剂量依赖性升高。

The antibiotic resistance of staphylococcus aureus was detected by K-B method. Of 33 staphylococcus aureus stains isolated from food, 28 were resistant to penicillium and ampicillin, the resistance rate was as high as 84.8%.21 stains were resistant to carbenicillin, the rate was 63.6%.5 stains were detected resistant to methicillin, which took up to 15.2%. The stains also were resistant to cephalosporin antibiotics, aminoglycoside, microcline antibiotic and tetracyclines in different levels, all strains were sensitive to vancomycin.

结果 33株食品中分离的金黄色葡萄球菌,有28株对青霉素和氨苄西林耐药,耐药率高达84.8%;21株对卡比西林耐药,耐药率达63.6%;检出了5株耐甲氧西林的菌株,耐药率为15.2%;对其他头孢类抗生素、氨基糖苷类、大环内脂类、四环素类等都出现出不同程度的耐药;所有菌株均对万古霉素敏感。

Taking mouse as the model animal, effect of tussah fibroin powder and ornithine mixture on fat metabolism and the ratio of liver weight to body weight was investigated.

以小鼠为试验动物,研究柞蚕丝素粉与鸟氨酸的混合物对酒精性脂肪肝肝体比和脂类代谢的影响。

Only under the sudden strike of extremely low temperature, such as -10癈,-20 癈, the cell membrane could be seriously damaged by lipid peroxidation.The variations in the content of main metabolic osmoregulatory substances, such as soluble sugars, protein and free proline were all tightly related to the cold resistance of podocarpus fleuryi Hickel seedlings.

只有极低温,如10oC、《0C的突然袭击下,细胞膜才会发生严重的膜脂过氧化作用长叶竹柏幼苗的主要代谢渗透调节物质,如可溶性糖类、游离脯氨酸和可溶性蛋白质含量变化都与长叶竹柏幼苗的抗寒性密切相关,但又不尽不同。

There was a little difference betweenphotosynthesis characteristic of the two varieties,response of Jiamusi to low temperature andpoor light was more sensitive than that of Longjiao No.2 and decreased pronouncedly withdecreasing light.6.EC and MDA of pepper leaves increased under low temperature and poor light,therewere no significant differences between them with decreasing light at 21-23℃/8-10℃,butthey were increased dramatically at 15-20℃/5-6℃.So we can speculate that lowertemperature was the direct reason resulted in cell membrane lipid peroxidation.7.No significant difference of SOD activity was observed under suboptimal temperatureand poor light21-23℃/8-10℃;150μmol·m~(-2·s~(-1),but SOD and POD activity substantiallydeclined with lowering temperature and light as well as treatment time.8.Under suboptimal temperature and lower light,proline accumulated to increaseosmotic regulation capacity and alleviate chilling damage.Soluble carbohydrate of pepper leaves decreased progressively and significantly with decreasing temperature and lightintensity as well as longer treatment time.So we think that synthesis and transport ofphotosynthetic product were inhibited by low temperature and poor light as solublecarbohydrate was important component of photosynthetic product.

两个供试辣椒品种之间的光合特性略有差异,佳木斯对低温弱光的反应比陇椒2号敏感,尤其随光照降低,其光合作用显著降低。6、低温弱光胁迫下,辣椒叶片的相对电导率和丙二醛含量都有不同程度的提高,在偏低温下,随着光照减弱,相对电导率和丙二醛含量差异不显著;在极端低温下,随着光照进一步减弱,相对电导率和丙二醛含量明显提高,随着处理时间延长,同一温度下,随着光照降低,叶片丙二醛含量也显著增加,由此可初步判断,低温是导致细胞膜脂过氧化的直接原因。7、经偏低温较弱光21~23℃/8~10℃、150μmol·m~(-2·s~(-1)处理后,辣椒叶片的超氧化物歧化酶活性变化与对照无显著差异,但随着温度、光强的逐步降低和处理时间的延长,SOD、POD活性显著降低。8、在偏低温较弱光下,辣椒能积累更多的脯氨酸,增强渗透调节,减轻低温冷害。

Human bladder cancer cell line T24 was used, two different NF-kB inhibitors, pyrrolidine dithiocarbamate and dominant negative IkBα were used.

在人膀胱癌细胞系T24中,使用两个核转录因子kB抑制剂即显性失活IkBα质粒和二硫氨甲酸脂吡咯烷。

AIM: To explore the effect of homocysteine-mediated endoplasmic reticulum stress on lipid metabolism in hepatocytes.

目的:探讨同型半胱氨酸介导的内质网应激对肝细胞脂质代谢的影响。

And it has also been demonstrated that acid sphingomyelinase, an enzyme responsible for hydrolyzing sphingomyelin to generate ceramide, could be activated at the same time.

同时,一种可以水解鞘脂类物质产生神经酰氨的酸性鞘磷脂酶往往在此过程被激活,这些过程对于胞内信号转导具有重要的作用。

Sphingomyelin is a kind of lipid, residing in the nature food and having latent function of inhibiting cancer. Sphingomyelin is metabolismed to ceramide and sphingosiine in the colon.

鞘磷脂是存在于天然食物中的一种具有潜在抑癌作用的脂类,在结肠内被代谢为神经酰胺和鞘氨醇。

As the precursor of sphingolipids, sphingosine is one of important constituents of cell membranes.

鞘氨醇是生物体内合成鞘脂的母体化合物,是生物膜中的重要组分之一。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

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