氨脂

Along with the fluconazole solution density rise,the experimental two kind of strain various glucose density is higher,showe d the glucose consumption are less,takes the logarithmof the medicine de nsity,discovered the logarithm the medicine density and each glucose den sity presents the linear relations;Carries on the analysis comparison to under the fluconazole function two kind of strain linear relations,disc overed the relations of the two strains has the nonuniformity.3 Compare the fluconazole induction reaiatance SC5314 strain and sens itive strain compares,its difference gene expression mainly concentrates in:The code proteinase body and the protein hydroltyic enzyme gene,in the code sugar fat metabolism process is connected the protein gene,the cell cycle correlation gene,the duplication and the translation adjustme nt correlation gene,the stress response correlation gene,the line plast ochondria correlation gene,the cell wall function related gene.4 Candida albicans SC5314 induction resiatance strain was processed b y Xianglian solution,its expression change gene mainly is:Code stress re sponse family protein gene,biomembrane relevant gene,a code proteinase body gene race,code cell cycle related protein gene,duplication and tra nslation adjustment related protein gene.5 The clinical reaiatance strain Candida albicans was processed by Xi anglian solution,its expression change gene mainly is:Codes the hot sho ck protein gene,the serine/threonine protein activating enzyme gene,the proteinase body family gene,the regulation copies and translates the ge ne.

随着氟康唑药液的浓度上升，试验的两种菌株各孔葡萄糖浓度越高，说明葡萄糖消耗越少，经过药物浓度取对数后进行分析，发现取对数后的药物浓度和每孔中葡萄糖浓度者呈现线性关系；对氟康唑作用下的两种菌株的线性关系进行分析比较，发现对两种菌株作用具有不一致性。3氟康唑诱导的耐药SC5314菌株与诱导前的敏感株相比，其差异基因表达主要集中在：编码蛋白酶体及蛋白水解酶的基因，编码糖脂代谢过程中相关蛋白的基因，细胞周期相关基因，转录及翻译调节相关基因，应激反应相关基因，线粒体相关基因，细胞壁功能相关基因。4白念珠菌SC5314诱导耐药株经香莲外洗液作用后，其表达变化的基因主要是：编码应激反应家族蛋白的基因，生物膜相关性基因，编码蛋白酶体基因一族，编码细胞周期相关蛋白基因，转录及翻译调节的相关蛋白基因。5白念珠菌临床耐药菌株经香莲外洗液作用后，其表达变化的基因主要是：编码热休克蛋白基因，丝氨酸/苏氨酸蛋白激酶基因，蛋白酶体家族基因，调控转录及翻译基因。

Wheat bran, organic rice, vegetable glycerin, natural spices, vegetable protein, glutamic acid, calcium carbonate, sodium caseinate, edible fatty acid – an acid glycerol ester, the green part of the chlorophyll, the green peppermint oil, peppermint oil, the white part of the essence for the milk, orange part of the essence for the unsaturated fatty acids – Omega-3 rich more and 6, sweet fennel seed, rosemary extract, vitamin C, zinc citrate.

小麦麸、有机米、蔬菜甘油、天然香料、植物蛋白、麸氨酸、碳酸钙、酪蛋白酸钠、可食的脂肪酸-甘油一酸脂、绿色部份为叶绿素、绿薄荷油、薄荷油、白色部份为牛乳菁华，橘色部份为不饱和脂肪酸菁华-富含更多的Omega-3 及 6、甜茴香籽、迷迭香萃取物、维他命C、柠檬酸锌。

MethodsPhotoaging skin fibroblast models were induced by 8-MOP/UVA. Cordyceps polysaccharides was administrated before 8-MOP/UVA .HE stained,MTT, hydroxyproline, MDA and SOD quantitant were used to test the effects of cordyceps polysaccharides. ResultsCell crimple,condensation of nuclear chromatin in 8-MOP/UVA model group were observed.

方法用8-甲氧补骨脂素联合UVA（8-MOP/UVA）诱导皮肤成纤维细胞光老化，用HE染色、MTT、羟脯氨酸含量、丙二醛含量检测及SOD活力分析等方法观察虫草多糖对成纤维细胞光老化过程中的形态、活力、胶原合成及抗氧化能力的影响。

OBJECTIVE: To investigate liposome-mediated cytosine deaminase gene transfecting rabbit BMSCs and its gene expression.

目的：探讨脂质体介导胞嘧啶脱氨酶基因转染兔骨髓间充质干细胞及其基因的表达。

OBJECTIVE: To investigate transfection and expression of liposome-mediated cytosine deaminase gene in rabbit BMSCs.

目的：观察脂质体介导胞嘧啶脱氨酶基因转染兔骨髓间充质干细胞及其表达。

To detect the marks reflecting the liver functions as follows:①The marks to reflect the capability to synthesize proteins, TPROT, ALB, GLB;②The marks to reflect the injury of the liver cells: AST, ALT, CHE;③The marks to reflect the capability to egest the bile, excrect, and detoxicate: TBILI, DBILI, IBILI, TBA;④The enzymes to reflect the cholestasis: GGT, ALP. Results The results of both the morphological and the pathological studies showed that the degree of the liver cirrhosis was of the terminal stage.

肝功能指标：①反映肝细胞蛋白合成代谢功能的指标：总蛋白TPROT，白蛋白ALB，球蛋白GLB；②肝细胞受损的指标；谷草转氨酶AST，谷丙转氨酶ALT，胆碱脂酶CHE；③反映肝脏胆排泄、分泌及解毒功能的指标：总胆红素TBILI，直接胆红素DBILI，间接胆红素IBILI，总胆汁酸TBA；④胆汁淤积指示酶：谷氨酰转肽酶GGT，碱性磷酸酶ALP。

AIM: To study the effect of glycine on body weight and lipid metabolism in mice.

目的： 观察甘氨酸对正常饮食和高脂饮食小鼠体重及血脂代谢的影响。

The method is right tall lipemia group (81) contrast with normal blood fat group (65), with analysis of appearance of gas phase color atlas all sorts of armour ester change the content of fatty acid of plaque phosphatide film, determine with standard method the thrombosis in blood endangers factor, serum is the same as model half Guang ammonia is acerbity and element of 11- dehydrogenation thrombus B2(TXB2), analyse the dependency between both with multivariate and linear regression.

方法对高脂血症组(81例)和正常血脂对照组(65例)，用气相色谱仪分析各种甲酯化血小板磷脂膜脂肪酸的含量，用标准方法测定血液中血栓形成危害因子，血清同型半胱氨酸及11-脱氢血栓素B2(TXB2)，并用多元线性回归分析二者之间的相关性。

Methods: Liver injure rat models were made by alcohol, the high-dose and low-dose ZhiGanQing Capsule were continuously watered by for 8 weeks, the contents of AST、ALT and TG were detected separatedly, and the hepatic pathology was observed too.

采用白酒复制大鼠肝损伤模型，脂肝清胶囊按高、低剂量灌胃，连续8周，测定血清天冬氨酸转氨酶、丙氨酸转氨酶及甘油三酯的含量，并观察肝脏的病理组织学改变。

However, fully consideration of special structure and physiological function of CRP is critical to investigate whether CRP provide protect effect or pathogenic effect in the progression of atherosclerosis. CRP is a member of pentrxins family, which consists of five identical, noncovalently associated 23-kDa protomers arranged symmetrically around a central pore with a 102 A external diameter. Each protomer has a recognition face with a phosphocholine binding site consisting of two coordinated calcium ions adjacent to a hydrophobic pocket. The opposite face of the pentamer is the effector face, where complement Clq binds and Fc receptors are presumed to bind. A cleft extends from the center of the protomer to the central pore of the pentamer. Both faces ofpentamer form a special bi-phase structure: one face is the ligand recognition phase, which can recognize apoptosis cells and enzyme modified low density lipoprotein in which PCh is exposed.

CRP是一种五聚体蛋白，外径为102 A，由5个相同的单体以非共价键结合，形成双面的环形结构，每个单体的配体识别位点或受体结合位点分别位于五聚体两个平面上，分别组成配体识别相和效应器相，从而构成特殊的二相性结构：一面为配体识别相，含有磷酸胆碱(phosphorycholine，PCh)结合位点，能够使CRP识别在病理条件下暴露出PCh的凋亡细胞、酶修饰低密度脂蛋白(enzyme modified low density lipoprotein，E-LDL)等。E-LDL是天然低密度脂蛋白(native Low density lipoprotein，N-LDL)在多种蛋白酶，如胰蛋白酶、神经氨酸酶、胆固醇酯酶等作用下的代谢产物，其主要特点是结构发生改变(N-LDL大小均匀，平均直径250±30 A，E-LDL大小差异极大，直径为100-2000 A)，暴露磷酸胆碱位点，能够被CRP识别；另一面为效应器相，能够与巨噬细胞、单核细胞表面受体FcγRⅡa结合，介导巨噬细胞、单核细胞识别及吞噬凋亡、坏死细胞作用。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。