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RESULTS:Planimetry of the luminal surface and intimal thickness of the aortae from high lipid group revealed a progressive increase.

结果:(1)高脂组斑块面积从8周末的37%上升到16周末50%,内膜从40 μm增厚到56 μm;(2)L-Arg组主动脉斑块面积和内膜厚度明显减少;(3)补充2.25%L-精氨酸8周,血清总胆固醇和丙二醛水平恢复正常,超氧化物歧化酶活性比高脂组高80%,比安慰剂组高60%。

Forβ-l,3-glucanase,its activity increased to peak level after 2 to 5 days and was 2.02 and 1.34 folds of check,then decreased rapidly and resumed to normal level after 5 and 9 days.Generally Psoralea corylifolia L.extract may enhance the activities of chitinase andβ-l,3-glucanase in cucumber leaves,then induce the enhancement of activities of defensive enzymes.

从所测定的几种酶活性变化时间来看,补骨脂提取物处理黄瓜幼苗后,首先,使黄瓜体内的几丁质酶和β-1,3-葡聚糖酶等病程相关蛋白活性升高,然后在两者的作用下,诱导了黄瓜体内过氧化物酶、多酚氧化酶、苯丙氨酸解氨酶等一些防御酶活性的提高。

Objective To synthesize new cationic liposome cytofectin N 4 spermine cholesteryl carbamate as a gene delivery vehicle for gene therapy of lung diseases.

目的 合成新型阳离子脂质体细胞转染素N4 精氨胆固醇羰酰氨,作为基因载体,用于肺部疾病的基因治疗。

The activity of superoxide dismutase in the myocardial cells was determined by the diphenol method, plasma malondialdehyde content was measured by TBA assay, the culture medium LDH content was measured by the acetonic acid method, the intracellular calcium concentration was measured by fluorescence spectropho- tometer- The results was shown that aspartate-K.

结果显示,门冬氨酸钾镁能减少阿霉素中毒心肌细胞乳酸脱氢酶的释放量,降低细胞内丙二醛含量及游离钙浓度,同时可升高细胞内超氧化物歧化酶活力;结果表明,门冬氨酸钾镁可能通过抗脂质过氧化及逆转细胞内钙离子过负荷作用进而保护中毒心肌细胞。

Emphasis: Aminolysis method of hydroxyl on alcohol, addition amination of epoxy alkyl, aminolysis of aliphatics haloid.

重点:醇羟基的氨解、环氧烷类的加成胺化、脂族卤素衍生物的氨解。

(1)PAL is better entrapped by PAG with a T∶C ratio of 8∶30.(2)PAL immobilized by glutaric dialdehyde on Bio-Gel P-300 is better than by CDC.(3)The best one is the dehydration and redehydration method.(4)Immobilized and permeated PAL active yeast cells are resistant to trypsin digestion and retain its PAL activity.

(1)固定化酶活性采用T∶C比为8∶30明显高于8∶19;(2)以戊二醛将PAL固定于Bio-GelP300优于用DCD固定化的酶;(3)质脂体包被中以脱水再加水法对酶活性影响较少,脂类组成以磷脂酰胆碱:胆固醇:磷脂酰丝氨酸比值7∶2∶1最好;(4)固定化PAL活性酵母细胞能较好地抵抗人工肠液中胰蛋白酶的水解作用,亦能明显降低苯丙氨酸的浓度。

Methods Rabbit model was adopted with gallstone induced by high cholesterol diet. Dynamic study on the serum lipoprotein cholesterol, hepatic total cholesterol, bile cholesterol and glycocholate, and low density lipoprotein recepter activity of hepatocytes had been conductd for the test and control groups after 1,2,3 and 4 weeks respectively.

采用高胆固醇膳食诱发兔胆囊结石模型,对进食高胆固醇膳食后1,2,3,4周实验组和对照组血清脂蛋白胆固醇、肝脏总胆固醇、胆汁中胆固醇和甘氨胆酸,肝细胞低密度脂蛋白受体活性变化进行了动态研究。

The results show that the hyperthyroidism group has elevated levels of choline, glucose and declined levels of VLDL, LDL, cholesterol, lactate, glycoprotein and alanine in serum samples relative to the healthy group. In urine samples, the hyperthyroidism group show increased levels of glucose, citrate, taurine and creatinine as well as decreased levels of hippurate, trimethylamine-N-oxide, formate and succinate.

结果表明,甲亢组血清中的胆碱、葡萄糖和三甲胺等物质的含量升高,而VLDL,LDL和胆固醇等脂质以及乳酸、糖蛋白和丙氨酸等代谢物的含量下降;甲亢组尿液中的葡萄糖、柠檬酸、牛磺酸以及肌氨酸等代谢物的含量升高,而马尿酸、TMAO、甲酸和琥珀酸等代谢物的含量下降。

Water, C12-20 acid PEG-8 ester, hydrogenated polysobutene, petrolatum, dicaprylyl maleate, hydrogenated vegetable oil, propylene glycol, acetylated lancolin, glycoprrotiens,panax ginseng root extract,equisetum arvense extract, carbomer, butyrospermum parkill fruit, potassium cetyl phosphate, triethanolamine, hypericum perforatum extract, malva sylvestris extract, methylparaben, glycerin, urea, saccharide hydrolysate, magnesium aspartate, glycine, alanine, creatine, propylparaben, ethlparaben, imidazolidinyl urea, polyperfluoromethylisopropyl ether, fragrance

水,C12-20 酸 PEG-8酯,氢化聚异丁烯,凡士林,马来酸二辛酯,氢化植物油,丙二醇,乙醯化羊毛脂,糖蛋白,人参根萃取,问荆萃取,卡波姆,乳木果,鲸蜡醇磷酸酯钾,三乙醇胺,金丝桃萃取,锦葵萃取,羟苯甲酯,甘油,尿素,水解糖,天门冬酸镁,甘氨酸,丙氨酸,肌酸,羟苯丙酯,羟苯乙酯,尿素醛,聚全氟甲基异丙基醚,香料

The proportion of GGT complexed with low density lipoproteins plus very-low density lipoproteins in total GGT in serum is determinated with ratio colorimetery,sodium phosphotungstate and MgCl2 as precipitation.26 patients with liver cancer,18 with liver cirrhosis,22 with chronic hepatitis,14 with the other malignant tumors,16 with non-hepatobiliary disease of high GGT and 50 healthy subjects have been evaluated.

本文以磷钨酸-氯化镁作沉淀剂,速率法测定血清低密度脂蛋白,极低密度脂蛋白结合的r-谷氨酰转移酶(LDL-VLDL-GGT)占总GGT的百分比。对临床26例肝癌、18例肝硬化、22例慢性肝炎、14例其他恶性肿瘤、16例GGT升高的非肝脏疾病及50例健康人进行了检测,结果表明:肝癌组明显高于其他各组,差异显著(P<0.01)。肝脏疾病升高幅度:肝癌>肝硬化>慢性肝炎,且每两者间有显著差异(P<0.01)。

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