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A phenylalanine ammonia-lyase gene was clone from Nerium oleander for the first time and it was also the first cloned gene involved in anthocyanin metabolic pathway in N.oleander.

首次从夹竹桃中克隆得到苯丙氨酸解氨酶基因cDNA片段,并命名为NoPAL1,GenBank登录号为AY747677,这也是首次从夹竹桃花青苷代谢途径中克隆得到的基因。

The process of selective reduction roasting- ammonia leaching is adopted to extract nickel,cobalt and recover iron from low grade nickeliferous laterite ore.

本研究采用选择性还原焙烧—氨浸工艺从低品位红土镍矿中综合提取镍、钴、铁,重点介绍了该工艺氨浸的试验研究。

Glioma is still one of refractory disease in the neurosurgical field; the development of new primary and adjuvant treatment is vital. Recently, the gene therapy of glioma is developed rapidly and there are many methods about the gene therapy that include: suicide gene therapy, immunologic gene therapy, drug resistangce gene therapy, angiostatin gene therapy and so on. The sucide gene therapy is the most potential approach of antitumer, these nonmammalian genes encode enzyme that convert nontoxic prodrugs into highly toxic metablites. Cells transfected with suicide genes are targeted for specific negative selection, witch can be induced by administrtion of the corresponding produg. Among the enzyme/produg combinations, two of the best characterized system are herpes simplex virus thymidine kinase /ganciclovir and Escherichia coli cytosine deaminase /5-flourocytosine (5-FC). The formor can convert the antiviral nucleoside analogs acyclovir , ganciclovir to their nucleoside monophosphate derivatives, the monophosphate forms are subsequently phosphorylated by endogenus cellular kinases to triphosphates, these molecules are potent inhibitors of DNA synthesis.

近年来脑胶质瘤的基因治疗发展迅速,应运而生的方法有自杀基因、免疫基因、多药耐药基因以及抗血管生成基因等,其中自杀基因被认为是最有前景的基因治疗方法,它又称病毒介导的酶/药物前体疗法,是利用转基因技术将哺乳动物细胞中所不含有的自杀基因转入到哺乳动物肿瘤细胞中,该基因表达的产物可将无毒的药物前体转化为毒性药物,从而选择性杀伤该肿瘤细胞,常用的自杀基因有单纯疱疹病毒-胸苷激酶基因和大肠杆菌胞嘧啶脱氨酶基因,前者催化无毒性抗病毒核苷类似物如丙氧鸟苷、无环鸟苷等成为单磷酸核苷衍生物,然后在内源性细胞激酶作用下转化为具有明显毒性的三磷酸核苷,作为DNA合成链的终止剂和DNA合成酶的抑制剂,干扰细胞DNA的合成;后者编码的胞嘧啶脱氨酶可催化5-氟胞嘧啶(5-FC)脱氨成为5-氟尿嘧啶(5-FU),然后代谢为有毒性的5-氟尿嘧啶-5′三磷酸(5-FUTP)和5-氟-2′脱氧尿嘧啶-5′磷酸(5-FdUTP),5-FUTP通过与UTP竞争性结合而抑制mRNA和tRNA的合成,5-FdUTP则作用于胸苷合成酶,导致TMP衰竭而阻止DNA的合成,最终诱导肿瘤细胞凋亡。

The reaction of inulin with octadecyl isocyanates resulted in carbamoylated inulins from which the interfacial properties were determined.

菊糖与十八烷基异氰酸酯在有机溶剂中发生甲氨酰化反应,生成的氨甲基菊糖具有表面活性。

The levels of blood glutamate-pyruvate transaminase, glutamic oxalacetic transaminase were measured and compared.

测定各血标本丙氨酸氨基转移酶、门冬氨酸氨基转移酶的变化并予以比较分析。

Through condensing o-aminobenzoic acid, ethyl oxalyl chloride and ethylenediamine(or 1,2-propylenediamine), two new ligands N-benzoato-N′-(2- aminoethyl)oxamido(H3oxbe) and N-benzoato-N-(2-amino-2-methylethyl)oxamido(H3oxbt) have been synthesized. Their mononuclear complexes Na·1.5H2O and Na·1.5H2O have also been obtained.

2以邻氨基苯甲酸、草酸乙酯酰氯和乙二胺(或1,2-丙二胺)缩合制得了两种具有不对称草酰胺结构配体N-(2-苯甲酰基)-N&-(2-氨乙基)草酰胺(H3oxbe)和N-(2-苯甲酰基)-N&-(2-氨丙基)草酰胺(H3oxbt),并得到了它们的单核配合物:Na·1.5H2O和Na·1.5H2O。

In the third part (chapter 3), the densities of glycine, L-alanine and L-serine in aqueous solutions of LiNO_3, NaNO_3, KNO_3, Na_2SO_4 and NaClO_4 have been measured at 298.15 K with an Anton Paar Model 55 densimeter.

第三章:用体积方法研究甘氨酸、L-丙氨酸和L-丝氨酸与LiNO_3、NaNO_3、KNO_3、Na_2SO_4和NaClO_4之间的相互作用。

Densities of L-glycine, L-alanine and L-serine have been measured withan oscillating-tube densimeter(Anton Paar Model DMA 55)at 298.15 K inwater/DMFand water/ethanol mixtures ranging from pure water to 45% DMFby mass.

同时,本文利用DMA 55振荡管密度计测定了298.15K时甘氨酸、L-丙氨酸和L-丝氨酸在纯水及水/DMF、水/乙醇混合溶剂(浓度范围为5~45%,以10%递增)中的密度。

Objective To explore the effect of NMDA receptor antagonist glutamyl amino-methyl phosphonic acid on the bilirubin neurotoxicity.

目的 探讨兴奋性氨基酸受体拮抗剂磷酸甲基谷氨酰氨酸对胆红素神经毒性的影响。

The invention is characterized in that absorbing agent is a multivariate compound salt which is formed by lithium nitrate, sodium thiocyanate and lithium rhodanate.

多元复合盐/氨溶液吸收制冷剂,它包括吸收剂和制冷剂,所述制冷剂为氨,其特征在于所述吸收剂为硝酸锂、硫氰酸钠和硫氰酸锂组成的多元复合盐。

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This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。

There is no differences of cell proliferation vitality between labeled and unlabeled NSCs.

双标记神经干细胞的增殖、分化活力与未标记神经干细胞相比无改变。