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Objective To study the mechanisms and treatment of ischemia /reperfusion injury, expression of intracellular adhesion molecule 1 (ICAM-1) and vascular cell adhesion molecule 1 (VCAM-1) were measured, the effect on suppression of ICAM-1 and VCAM-1 by the pyrrolidine dithiocarbamate were investigated.

目的 为研究心肌缺血-再灌注损伤的机制和治疗途径,检测血管内皮细胞缺氧/再给氧后细胞间黏附分子- 1(intracellular adhesion molecule1,ICAM- 1)和血管细胞黏附分子- 1(vascular cell adhesion molecule1,VCAM-1)的表达,探讨抗氧化剂吡咯烷二硫氨基甲酸酯(pyrrolidine dithiocarbamate,PDTC)对血管内皮细胞表面细胞黏附分子表达的抑制作用。

METHODS:After the treatment of TRAIL or LPS at different doses,we tested the nuclear translocation of NF-κB by cell immunohistochemical staining and electrophoretic mobility shift assay,and evaluated the level of IκB by RT-PCR under pyrrolidine dithiocarbamatetreatment.

当不同浓度的TRAIL和LPS作用于细胞后,我们通过细胞免疫组化染色和凝胶电泳迁移试验来检测NF-κB核转位的情况。并通过RT-PCR的方法粗略评定二硫代氨基甲酸吡咯烷对抑制蛋白IκB的影响。

Objective To develop a RP-HPLC method for the enantiomeric separation of indapamide on a new chiral column CHIRALCEL OD-RHcellulose tris(3,5-dimethylphenylcarbamatecoated on a5μm silica-gel substratefor pharmaceutical study of indapamide.Methods To obtain optimistic method for the enantiomeric separation of indapamide,the inferences of the composition of mobile phase,the flow rate and the temperature on the enantiomer retentivity and selectivity were examined and discussed.

目的采 用新型反相手性色谱柱CHIRALCEL OD-RH(纤维素3,5-二甲基苯基氨基甲酸酯涂敷在5μm硅胶上),建立吲达帕胺对映体的反相高效液相色谱拆分方法,为研究吲达帕胺手性对映体药代动力学提供基础。

Water, Sweet almond oil, Cetearyl wheat bran glycosides and cetearyl alcohol, Hydrogenated jojoba oil, Zinc oxide, Rosehip oil, Evening primrose oil, Macadamia nut oil, Calendula oil, Honey, Camellia oil, Rose geranium oil, Frankincense oil, Lavender oil, Grapefruit seed extract, Vitamin E,marshmallow root,ginkgo bilboa, Phenoxyethanol, Iodopropynyl butylcarbonate.

水,甜杏油,麦秸鲸蜡硬脂基葡糖苷和十六烷基醇,氢化霍霍巴油,氧化锌,野玫瑰果籽油,月见草油,澳洲坚果油,金盏菊油,蜂蜜,山茶油,老鹳草玫瑰油,乳香油,薰衣草油,药属葵根,百果树,苯氧乙醇,碘代丙炔基氨基甲酸

Water, glycerin and glyceryl stearate SE, cetearyl wheat straw glycosides, cetearyl alcohol, rosehip oil, evening primrose oil, jojoba oil, almond oil, aloe vera, carrot oil, orange flower oil, grapefruit seed extract, vitamin e, chamomile oil, rose geranium oil, frankincense oil, lavendar oil, phenoxyethanol, iodopropynyl butylcarbamate

十六烷基醇,野玫瑰果籽油,月见草油,霍霍巴油,杏仁油,芦荟,胡萝卜油,橙花油,葡萄籽精华素,维生素E,甘菊油,玫瑰老鹳草油,乳香油,熏衣草油,苯氧乙醇,碘代丙炔基氨基甲酸丁。

Calcium carbonate and soluble glass and so on were confected as alkaline antifouling agent. The Infrared Spectrometry results showed that 2275-2250 cm~(-1) diagnostic absorb wave crest in part A and 3390-3200 cm~(-1) in part B and 1730 cm~(-1) in coating film strongly proved polymers reacted just as the reacting mechanism, that means polysiloxane which offer low-surface-energy property linked Polyurethane system by —OH groups reacting with —NCO groups. Relative molar mass of part A and part B was determined by Gel Permeation Chromatography and the results were appropriate. Surface-energy was determined and results were between 33.6-47.17 mN/m and it increased when alkaline antifouling agent was put into the coating. Alkaline antifouling agent was releasing steadily when the coating film was dipped in seawater. As time gone, the pH value of seawater was increasing. Solubility parameter and results showed that there was no corrasive phenomenon between the polyethylene strand and the coating.

红外光谱分析结果表明,出现在A组分中的2275~2250cm~(-1)处的异氰酸酯特征吸收峰、B组分中的3390~3200cm~(-1)处硅羟基的特征吸收峰及出现在固化后涂膜中的1730cm~(-1)处氨基甲酸酯基团的特征吸收峰证明了涂料成膜物质交联固化符合本文的设计要求,即赋予涂膜低表面能特性的有机硅组分通过—OH基团与—NCO基团的反应已经链接到聚氨酯体系中;凝胶渗透色谱结果表明,成膜物质的A、B组分均为低分子量,符合预聚物的要求;涂膜表面能的测算结果表明,涂膜的表面能在33.6~47.17mN/m之间;加入碱式防污剂后涂膜的表面能略有升高;碱式防污剂的释放平稳,随着涂膜在海水中浸泡时间的增长,pH值有增加的趋势;用溶解度参数原则来评价涂料与网绳的涂装,结果表明,本试验研制的防污涂料对聚乙烯网绳无溶蚀作用。

The central integrative part of the baroreflex receives afferent information not only from the sino-aortic baroreceptors, but also from various other sources. The present study was to investigate the effect of somatic nerve stimulation on baro-reflex. The exoeriment was performed in α-chloralose-urethane anesthetized rabbits. Intrasi- nusal pressure -mean arterial pressure res- ponse curves were constructed.

在自然状态下,各种传入冲动汇集中枢,很多传入冲动都可影响压力感受性反射,使压力感受性反射受到调制而发生重新调定·本实验旨在观察刺激躯体神经对压力感受性反射的重调定并分析其机制·实验在α-氯醛糖和氨基甲酸乙酯混合麻醉的家兔上进行,利用颈动脉窦灌流技术测量不同窦内压时体循环平均动脉压的水平,并画出窦内压-体循环平均动脉压反应曲线。

Clinicians should be able to recognize and treat significant toxidromes resulting from acetaminophen; anticholinergic agents including antihistamines and psychoactive drugs; anticoagulants such as warfarin or rat poison; cardiac medications including calcium channel blockers, beta-blockers, and digoxin; muscarinic cholinergic agents including carbamates, some mushrooms, and organophosphates; nicotinic cholinergic agents such as insecticides and nicotine; cyanide; ethylene glycol or methanol from antifreeze or rubbing alcohol; iron-containing products such as deferoxamine; opioids such as morphine, hydrocodone, or methadone; salicylate (aspirin-containing products); sulfonylurea; and sympathomimetic agents such as amphetamines, caffeine, cocaine, or ephedrine.

医师必须可以辨识与治疗乙醯胺酚;抗胆碱剂,如抗组织胺与精神作用药物;抗凝血剂,如warfarin或杀鼠剂;钙离子阻断剂、乙型阻断剂、毛地黄等心脏药物;蕈毒胆碱剂,如氨基甲酸酯盐、某些有毒蘑菇、有机磷农药;菸碱性胆碱剂,如杀虫剂与尼古丁;氰化物;抗冻剂或外用酒精的乙二醇或者甲醇;含铁产品,如 deferoxamine;鸦片类,如吗啡、hydrocodone、美沙冬;水阳酸;硫醯基尿素类降血糖药;拟交感神经药物,如安非他命、咖啡因、古柯碱或麻黄素等造成的明显中毒症候群。

It has operating safety, curing speed is slow when it is used alone. The curing speed can be arised when used with thiazole, thiuram, thiocarbamate.

操作安全,单独使用时硫化速度慢,与噻唑类、秋兰姆类及二硫代氨基甲酸盐并用能提高硫化速度。

Purified water, Vegetable glycerine, Avocado oil, Cetearyl wheat straw glycosides and cetearyl alcohol, Vegetable glycoerol stearate, Evening primrose oil, Rosehip oil, Calendula oil, Vitamin E, Vitamin A palmitate, Green tea leaf extract, Ginkgo biloba extract, Grapefruit seed extract, 100% natural fragrance (essential oil blend of orange blossom, ylang ylang, rose, jasmine, tonka bean), phenoxyethnol, Iodopropynyl butylcarbamate.

纯水, 蔬菜甘油,鳄梨油,麦秸鲸蜡硬脂基葡糖苷和十六烷基醇,蔬菜银杏硬脂酸,月见草油,野玫瑰果籽油,金盏菊油,维生素E ,维生素A棕榈酸酯,绿茶叶提取物,银杏叶提取物,葡萄柚籽提取物, 100 %天然香料(精油混合橘子的花,依兰依兰,玫瑰,茉莉花,零陵香豆),苯氧乙醇,碘代丙炔基氨基甲酸

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