氨基比林

The linear ranges for aminopyrine,antipyrine and barbital were 1.67～333 mg/L,133～667 mg/L,60～300 mg/L respectively.

氨基比林、安替比林、巴比妥线性范围分别为1.67~333、133~667、60~300 mg/L，检出限分别为1、4、12 mg/L。

Both the number of input nodes and hidden nodes was 5.Refrence solution was mixure of aminopyrine and antipyrine.

输入节点数和隐含节点数均为5，测定参比液为氨基比林和安替比林的混合液。

Refrence solution was mixure of aminopyrine and antipyrine.

输入节点数和隐含节点数均为5，测定参比液为氨基比林和安替比林的混合液。

And containing aminopyrine aminopyrine drugs.

氨基比林及含氨基比林的药物。

METHODS:Aminopyrine and antipyrine in Antongding injection were determined by radial basis fuction neural network UV spectrophotometry,barbitial was determined with absorbance substraction technique.

采用径向基函数紫外分光光度法同时测定安痛定注射液中的氨基比林和安替比林，并结合吸光度减技术测定巴比妥。

A method based on liquid phase microextraction with gas chromatography-flame ionization detector was established for the determination of aminopyrine,antipyrine and barbital in Urine.

建立了一种以液相微萃取(Liquid Phase Microextraction，LPME)与气相色谱-氢火焰(LPME-GC-FID)联用技术为基础的测定尿样中氨基比林、安替比林和巴比妥的方法。

The transfer behavior of pyrazolone derivatives, such as antipyrine, aminopyrine, 4-aminoantipyrine and analgin, across the W/NB interface was investigated. The three medicines studied can form complex with a proton and the complex formed can transfer reversely across the W/NB interface and the transfer process was controlled by diffusion. The transfer of protonated analgin was not observed within potential window because of its high transfer potential.

研究了吡唑啉酮类的安替比林、氨基比林、4-氨基安替比林和安乃近四种药物在W/NB界面的转移行为，前三种药物在一定pH值的水溶液中结合一个质子形成1∶1质子配合物，并能在W/NB界面发生可逆转移，其转移过程受扩散控制，安乃近的质子化物由于有较高的转移电位而未在电位窗内观察到其转移峰。

On the other hand, the hepatic microsomal aminopyrine demethylase activity was obviously inhibited 2 hours after administration of the same dose of SY-801 and SY-640, while the content of hepatic cytochrome P-450 was not affected.

体外实验表明，SY-801和SY-640对正常小鼠、3-甲基胆蒽（3-MC）处理小鼠及苯巴比妥处理小鼠小鼠肝微粒体氨基比林脱甲基酶活性都具有明显的抑制作用，其中对3-MC处理小鼠肝微粒体氨基比林脱甲基酶活性抑制作用最显著。

In order to study the relation of cytochrome P-450 with the protective action of SY-801 and SY-640 against 〓-induced UDS and 3H-BP binding to nuclear DNA, the effects of SY-801 and SY-640 on liver microsomal cytochrome P-450 were studied in mice. The results indicated that the liver microsomal cytochrome P-450 concentration and aminopyrine demethylase activity were significantly increased in mice pretreated with SY-801 150mg/kg or SY-640 150 mg/kg once daily for three days.

本实验进而观察了SY-801对小鼠肝微粒体细胞色素P-450酶系的影响，结果表明SY-801和SY-640体内连续给药3天，可诱导小鼠肝微粒体细胞色素P-450含量明显增加，同时氨基比林脱甲基酶活性亦明显增加；给药1次2小时内二者均可抑制氨基比林脱甲基酶活性，而对肝微粒体细胞色素P-450含量则无明显影响。

Benzene-acetone (4:1,V/V)was used as developing agent to soparate amidopyrine and barbitone from the compound amidopyrine injection solution on the silica G plate,and Dual wave thin-layer chromatographic densitometry was used to determine amidopyrine (λ_s = 270nm,λ_R=340nm)and barbitone (λ_x=205nm,λ_R=320nm).

以苯-丙酮(4：1，V/V)为展开剂，在薄层硅胶板上将复方氨基比林注射液中的氨基比林和巴比妥分离后，通过双波长扫描测出氨基比林(λ_s=270nm，λ_R=300nm)和巴比妥(λ_s=205nm，λ_R=320nm)的含量

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。