氨基己糖

We investigated constituent of triterpenoid saponins ofAlbizzia, two new compounds together with two known compounds were isolated from Albizzia julibrissin Durazz. by using column chromatography (macroreticular resin, silica gel, Sephadex gel, reverse phase silica gel),preparative HPLC methods et al.On the basis of spectroscopic analysis, including IR,ESI-MS,~1H-NMR,~(13)C-NMR,HMBC,HMQC,~1H-~1HCOSY and chemical methods, the structure of two new compounds were identified as 3 - O -[β-D-xylopyranosyl(1→2)-β-D-fucopyranosyl (1→6)-β- D -2- deoxy - 2 - acetoamidoglucopyranosyl] -21-O-[(6S)-2- trans- 2,6-dimethyl - 6 - O-β- D - quinovopyranosyl -2,7- octadienoyl] - acacic acid- 28 - O-β-D-glucopyranosyl(1→3)[α-L-arabinofuranosyl(1→4)]-α-L-rhamnopyranosyl(1→2)-β-D-glucopyranoside acacic acid 3- O -β- D- glucopyranosy(1→3)-β- D- fucopyranosl(1→6) [β-D- xylopyranosyl (1→2)]-β-D-glucopyranoside ;two known compounds were acacic acid lactone 3- O -β-D- xylopyranosyl-(1→2)-β-D-fucopyranosl (1→6)- 2-deoxy -2 -acetoamido -β-D- glucopyranoside ; acacic acid lactone 3- O-β-D-xylopyranosyl(1→2)-α-L- arabinopyranosl (1→6)- 2- deoxy - 2- acetoamido -β-D-glucopyranoside . The study lays chemical foundation and chemical reference substance for enhancing quality standard of Albizzia julibrissin Durazz.

本研究论文在综述国内外对合欢属Albizzia三萜皂苷化学成分和药理作用研究进展的基础上，利用传统植化分离手段和现代分离技术，包括大孔树脂、硅胶、葡聚糖凝胶、反相硅胶等柱色谱，制备高效液相色谱法等技术从中药合欢皮中分离得到了4个化合物，其中，2个新化合物和2个己知化合物，并进一步通过现代分析技术IR，ESI-MS，~1H-NMR，~(13C-NMR，HMBC，HMQC，~1H-~1HCOSY等和化学方法鉴定了2个新化合物的结构分别是：3-O-[β-D-吡喃木糖基(1→2)-β-D-吡喃夫糖基(1→6)-β-D-2-去氧-2-乙酰氨基吡喃葡萄糖基]-21-O-[(6S)-2-反式-2，6-二甲基-6-O-β-D-吡喃鸡纳糖基-2，7-辛二烯酸基]-金合欢酸-28-O-α-L-呋喃阿拉伯糖基(1→4)[β-D-吡喃葡萄糖基(1→3)]-α-L-吡喃鼠李糖基(1→2)-β-D-吡喃葡萄糖苷，金合欢酸3-O-β-D-吡喃葡萄糖基(1→3)-β-D-吡喃夫糖基(1→6)[β-D-吡喃木糖基(1→2)]-β-D-吡喃葡萄糖苷；2个已知化合物结构分别是：金和欢酸内酯3-O-β-D-吡喃木糖基(1→2)-β-D-吡喃夫糖基(1→6)-β-D-2-去氧-2-乙酰氨基吡喃葡萄糖苷，金和欢酸内酯3-O-β-D-吡喃木糖基(1→2)-α-L-吡喃阿拉伯糖基(1→6)-β-D-2-去氧-2-乙酰氨基吡喃葡萄糖苷。

Mission:"equality and mutual benefit, reputation first, unity and cooperation and friendship between the long-term" supply products: ethylenediamine; diethylamide; triethylamine; Diethylenetriamine; three ethylene diamine; three ethylene amines 40; 40 Five ethylene amines; five ethylene amines 6; caprolactam; DMF; allyl amine; N, N dimethylaniline; propylamine; are butylamine; are TOA; 3 Poly Cyanamide; 1,2 c diamine; ethanolamine; diethanolamine, triethanolamine; potassium iodide, potassium hydroxide, potassium permanganate, toluene, xylene, toluene of chlorine ; Acetone, butanone; acetylacetone; ethyl acetate, butyl acetate; Y-butyrolactone; DMC; acetyl of methyl acetate; Sanfu acetyl acid; Sanfu acetyl B Ethyl; methanol, ethanol, isopropanol; propylene glycol; glycerol; propargyl alcohol; 1.3 propylene glycol; xylitol; acetic acid; have acid; mercaptoacetic acid; vary Bitterness; adipic acid; trifluoroacetic acid; oxalic acid, the amino acid; o-amygdalin acid; DL-Acid; anhydrous piperazine; six non-piperazine, furfural, castor oil, ethylene Aldehyde; glutaraldehyde, multi-POM; isopropyl ether; anisole; tetrahydropyrrole; pure pyridine; 1.2 dichloroethane; methylene chloride, chloroform, carbon tetrachloride; hydrazine hydrate; Nonylphenol;-m-cresol; Se phenol; phenol; the tert-butyl phenol; Titanium Dioxide; iron; full Tangfen; Bisphenol A; azo two different nitrile; sodium azide; sodium carbonate ; Sodium chloride; iron oxide; cuprous chloride; thionyl chloride; D4; sodium bicarbonate; ammonia, potassium chloride; anhydrous sodium sulphite; ammonium persulfate; glycol Dingmi; B Glycol ether; calcium chloride; cyclohexanone; cyclohexane, methyl tertiary butyl ether, potassium carbonate, ferric chloride, potassium nitrate; Linsuansanna; zinc oxide; sodium nitrite; antimony oxide; Tartrate; OP-10; TX-10; tablets base; AES; sodium benzoate, sodium citrate; partial sodium silicate, sodium perborate, a sodium carbonate, sodium benzene; Asia sodium chlorate; Wuluo Care products; urea; hydrochloric acid, sulfuric acid, lactic acid; amino acid, hydrogen peroxide, ammonium bicarbonate

公司宗旨："平等互利，信誉至上，团结合作，友谊长久"乙二胺；二乙胺；三乙胺；二乙烯三胺；三乙烯二胺；三乙烯四胺；四乙烯五胺；五乙烯六胺；己内酰胺；二甲基甲酰胺；烯丙基胺；N，N二甲基苯胺；正丙胺；正丁胺；正辛胺；三聚氰胺；1，2丙二胺；一乙醇胺；二乙醇胺；三乙醇胺；碘化钾；氢氧化钾；高锰酸钾；甲苯；二甲苯；对氯甲苯；丙酮；丁酮；乙酰丙酮；醋酸乙酯；醋酸丁酯；Y-丁内酯；碳酸二甲酯；乙酰乙酸甲酯；三伏乙酰乙酸；三伏乙酰乙酸乙酯；甲醇；无水乙醇；异丙醇；丙二醇；丙三醇；丙炔醇；1.3丙二醇；木糖醇；冰醋酸；己醛酸；巯基乙酸；异辛酸；己二酸；三氟乙酸；乙二酸；对氨基苯乙酸；邻氯苦杏仁酸；DL-扁桃酸；无水哌嗪；六无哌嗪；糠醛；蓖麻油；乙二醛；戊二醛；多聚甲醛；异丙醚；苯甲醚；四氢吡咯；纯吡啶；1.2二氯乙烷；二氯甲烷；三氯甲烷；四氯化碳；水合肼；壬基酚；纯间甲酚；硒酚；苯酚；对叔丁基苯酚；钛白粉；铁粉；全糖粉；双酚A；偶氮二异丁腈；叠氮化钠；碳酸钠；氯化钠；三氧化二铁；氯化亚铜；氯化亚砜；D4；碳酸氢钠；氨水；氯化钾；无水亚硫酸钠；过硫酸铵；乙二醇丁醚；乙二醇乙醚；氯化钙；环己酮；环己烷；甲基叔丁基醚；碳酸钾；三氯化铁；硝酸钾；磷酸三钠；氧化锌；亚硝酸钠；氧化锑；酒石酸；OP-10；TX-10；粒碱；AES；苯甲酸钠；柠檬酸钠；偏硅酸钠；过硼酸钠；过碳酸钠；苯磺酸钠；亚氯酸钠；乌洛托品；尿素；盐酸；硫酸；乳酸；氨基磺酸；双氧水；碳酸氢铵

The molecular compositions of PCE-CGH and PCE-CGL were investigated by chromatography and chemical analysis. Rhamnose, arabinose, glucose and galactose were proved to be the main strctural unit of PCE-CGH, and trifle glucoronic acid was identified in the molecule. The compositions of PCE-CGL were relatively complicated. Inositol and amino sugars besides for glucose and galactose were also identified in its molecule.

其中，PCE-CGH主要是以鼠李糖、阿拉伯糖、葡萄糖和半乳糖为结构单元的大分子多糖类物质，并含有少量的己糖醛酸；PCE-CGL的分子组成相对复杂，除含有葡萄糖和半乳糖外，还含有一定量的肌醇和氨基糖。

Methods:Thirtytwo rats were randomly divided into four groups(normal control group,celiac seawaterimmersing trauma stress 1,2,3h groups).The amount of hexosamine and phospholipids in gastric mucosa of rats were detected by both chemochromometric and modified chemical methods.

32只SD大鼠随机分成正常对照组和腹腔浸泡伤1h、2h、3h 4组，分别取相应大鼠的胃黏膜，采用化学比色法和改良抗坏血酸法测定胃黏膜中氨基己糖和磷脂含量。

Results:Compared with normal rats,both hexosamine and phospholipids in gastric mucosa of rats under celiac seawaterimmersing trauma are progressively decreased(P0.05),especially in stress 3h group.

海水浸泡伤是一损伤性因素，通过减低胃黏膜中氨基己糖和磷脂含量而损害腹腔浸泡伤的大鼠胃黏膜屏障。

Seawater immersing trauma is a harmful factor,it deteriorates gastric mucosal barrier in rats with open abdominal trauma after seawater immersion through lowering the content of hexosamine and phospholipids.

海水浸泡伤是一损伤性因素，通过减低胃黏膜中氨基己糖和磷脂含量而损害腹腔浸泡伤的大鼠胃黏膜屏障。

AIM: From the views of biochemistry, histology and molecular biology, this study observed the effects of 4-6 Hz vibration on concentration of hexosamine, the expression of mucin 5AC mRNA in gastric mucosa and histomorphology, and investigated the effects of body vibration on rats' gastric mucus secretion and mucosal structure.

邓 艳，陈伟华，宋小丹，张源淑南京农业大学动物医学院，农业部生理生化重点开放实验室，江苏省南京市 210095目的：从生物化学、组织学和分子生物学角度观察4~6 Hz振动对大鼠胃黏膜氨基己糖含量、黏蛋白5AC mRNA表达及其组织形态学变化，探讨振动对大鼠胃黏膜黏液分泌及形态的影响。

Then the tissue and blood samples were obtained and measured.Result: In the muscovite group,restored mucosa thickness increased,cystically dilated glands decreased,microvessels in connective tissue increased,the secretion of mucus,hexosamine, PGE2,EGF,bFGF were enhanced,and the express of EGFR was stronger.

结果：经云母治疗后，大鼠再生黏膜厚度增加、囊状扩张腺体数目减少，肉芽组织炎症细胞浸润数量减少、微血管数量增加、胶原面积增加，黏膜中性黏液和氨基己糖分泌增多，血浆PGE2，EGF分泌增多，免疫组化染色中黏膜局部EGFR，bFGF阳性细胞表达增强。

Results: The lower ulcer index and increased ulcer inhibition rate were observed in OME and OME + TEP groups. In TEP and OME + TEP groups, restored mucosa thickness increased, cystically dilated glands decreased, microvessels in connective tissue increased, the secretion of mucus, hexosamine, PGE2, bFGF were enhanced, the expression of EGFR was increased.

替普瑞酮组和联合治疗组大鼠再生黏膜厚度增加、囊状扩张腺体数目减少，肉芽组织炎症细胞浸润数量减少、令微血管数量增加、胶原面积增加，黏膜中性黏液和氨基己糖分泌增多，血浆PGE2分泌增多，免疫组化染色中黏膜局部EGFR、bFGF阳性细胞表达增强。

be good at stomach heals sore piece the action mechanism that fights gastritis may have the following: Pump 餒 P, reduce the expression of PAF, influence stomach mucous membrane amino oneself candy and phosphatide content, affect hydrophoby of gastric mucous membrane, reinforce stability of mucus gel layer, prevent the generation of gastritis and recrudesce thereby.

结论健胃愈疡片抗胃炎的功能机理可能有以下几点：杀灭HP，下调PAF的表达，影响胃黏膜氨基己糖及磷脂含量，影响胃粘膜疏水性，加强黏液凝胶层稳定性，从而防止胃炎的产生和复发。

Do you know, i need you to come back

你知道吗，我需要你回来

Yang yinshu、Wang xiangsheng、Li decang,The first discovery of haemaphysalis conicinna.

1〕 杨银书，王祥生，李德昌。安徽省首次发现嗜群血蜱。